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The map label for this gene is dinF [H]

Identifier: 194736298

GI number: 194736298

Start: 4310543

End: 4311868

Strand: Direct

Name: dinF [H]

Synonym: SeSA_A4430

Alternate gene names: 194736298

Gene position: 4310543-4311868 (Clockwise)

Preceding gene: 194738283

Following gene: 194736080

Centisome position: 91.54

GC content: 56.94

Gene sequence:

>1326_bases
ATGCCGCTTTTTACCTCCTCTGATAAAGCTCTCTGGCGTCTCGCGCTGCCGATGATTTTTTCTAACATCACCGTCCCCTT
ACTGGGGCTGGTTGATACGGCGGTGATTGGTCATCTGGACAGCCCGGTTTTCCTGGGCGGCGTGGCGGTGGGCGCGACTG
CCACCAGCTTTCTTTTCATGCTGCTGCTATTTCTACGTATGAGCACCACCGGACTAACGGCGCAGGCATTTGGCGCCAAA
AATCCGCAGGCGTTAGCCCGGGCGCTCATTCAACCGTTATTGCTGGCACTGGGCGCTGGCGTGATGATTGTGCTATTTCG
CACGCCGCTTATCGAGCTGGCTTTACATATTGTCGGCGGGAACGACGCTGTCCTGGTGCAGGCGAGACGCTTCCTTGAAA
TTCGTTGGCTAAGCGCTCCCGCGTCACTGGCGAATCTGGTGCTGCTCGGGTGGCTGTTAGGCGTTCAGTATGCGCGGGCG
CCGGTTATCTTGTTGGTCGTGGGCAATATCCTCAACATCGCGCTCGACCTGTGGCTGGTGATGGGACTTCATATGAACGT
GCAGGGCGCCGCCCTGGCGACGGTCATCGCAGAATATGCCACATTACTGATCGGCTTTATGATGGTACGTAAAGTTCTCC
ATCTCCGCGGTGTGTCGCTGGATATGCTAAAACAGGCCTGGCGCGGCAACGTGCGCCGCCTTTTAGCGCTCAATCGCGAT
ATCATGCTGCGCTCATTGCTCCTTCAGCTTTGTTTTGGCGCAATCACGGTGTCAGGCGCGCGGCTGGGCAGCGATATTAT
CGCGGTAAATGCAGTCCTGATGACCTTACTCACCTTTACGGCCTATGCGCTGGACGGTTTTGCTTATGCGGTGGAGGCGC
ACTCCGGTCAGGCTTACGGCGCGCGTGACGGTAGCAAGCTACTGGACGTCTGGCGAGCGGCGTGTCGTCAGTCAGGAATT
GTGGCCTTGTTGTTTTCCACAGTCTATGCCCTGGCAGGCGAACATATTGTCGCGTTACTGACCTCATTGCCGCAAATACA
GCTACTGGCGGATCGGTATCTTATCTGGCAGGTGGTATTACCGCTGGTGGGCGTATGGTGCTATCTGCTCGACGGTATGT
TTATTGGCGCGACGCGCGCTGCCGAAATGCGCAATAGCATGGCTGTCGCCGCGGGAGGATTCGCGCTGACGCTCTTCGCT
CTGCCGGTATTAGGAAATCATGGTTTATGGCTGGCATTAACCGTGTTCCTGGCGCTTCGCGGTCTGTCGTTGAGCCTTAT
CTGGCGTCGTCACTGGCGCGAGGGTACATGGTTTGCCAGATCGTGA

Upstream 100 bases:

>100_bases
ATGCAGTTCCTGAGATGATTAATTTGTAGGCCGGATAAGGCGTTACGTCGCCATCCGGCAATGCGCTCGTTTCGTTTAAC
TCCTTGTCAGGCTTTTCTCC

Downstream 100 bases:

>100_bases
CGGTTAAAAATTCTGAATATAAAACCGAAGGCCGAATTCCTGCCTACAATTATTATCACGTCCAGCAGAAATTGCAGTGC
ATTTGGGCGAATAACACCTG

Product: DNA-damage-inducible SOS response protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MPLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAK
NPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
PVILLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRD
IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGI
VALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFA
LPVLGNHGLWLALTVFLALRGLSLSLIWRRHWREGTWFARS

Sequences:

>Translated_441_residues
MPLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAK
NPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
PVILLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRD
IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGI
VALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFA
LPVLGNHGLWLALTVFLALRGLSLSLIWRRHWREGTWFARS
>Mature_440_residues
PLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKN
PQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAP
VILLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRDI
MLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIV
ALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFAL
PVLGNHGLWLALTVFLALRGLSLSLIWRRHWREGTWFARS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=439, Percent_Identity=89.5216400911162, Blast_Score=711, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47772; Mature: 47641

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHH
LLLFLRMSTTGLTAQAFGAKNPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGG
HHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHCCC
NDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIALDLWLV
CCEEEHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MGLHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYG
HHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
ARDGSKLLDVWRAACRQSGIVALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFALPVLGNHGLWLALTVFLALR
HHHHHHHHHHCCHHHCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GLSLSLIWRRHWREGTWFARS
CCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHH
LLLFLRMSTTGLTAQAFGAKNPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGG
HHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHCCC
NDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIALDLWLV
CCEEEHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MGLHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYG
HHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
ARDGSKLLDVWRAACRQSGIVALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFALPVLGNHGLWLALTVFLALR
HHHHHHHHHHCCHHHCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GLSLSLIWRRHWREGTWFARS
CCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]