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The map label for this gene is tatD [H]

Identifier: 194736264

GI number: 194736264

Start: 4060504

End: 4061298

Strand: Direct

Name: tatD [H]

Synonym: SeSA_A4184

Alternate gene names: 194736264

Gene position: 4060504-4061298 (Clockwise)

Preceding gene: 194736563

Following gene: 194735887

Centisome position: 86.23

GC content: 54.84

Gene sequence:

>795_bases
ATGGGGGCAAGCATGTTTGATATTGGCGTTAATTTAACCAGTAGCCAGTTTGCAAAAGATCGTGATGATGTGGTCGCCCG
TGCGTTTGCGGCGGGAGTAAAAGGTATGCTACTGACCGGAACGAACATCCATGAAAGCCAGCAGGCGTTAAAACTGGCGC
GGCGCTACCCCCATTGTTGGTCGACGGCTGGCGTCCATCCCCATGACAGCAGTCAGTGGTCATCCGCGTCTGAAGACGCC
ATTATTGCGCTGGCGAACCAGCCGGAAGTCGTCGCTATCGGTGAGTGCGGGCTGGATTTCAATCGCAATTTTTCCACGCC
GCAGGAGCAGGAGCGTGCCTTTCAGGCGCAGCTACAAATTGCCGCCGAATTGCAGATGCCAATCTTTATGCACTGCCGGG
ACGCGCATGAGCGATTTCTGGCATTGCTTGATCCCTGGCTGGATAGTCTTCCTGGTGCAATACTGCACTGCTTTACCGGT
TCACGCCAGCAAATGCAGGCCTGTGTGGACAGAGGGCTCTATATCGGTATTACCGGGTGGGTTTGCGACGAACGACGCGG
GCTTGAGCTACGTGAACTCTTACCGTTTATTCCAGCGGAAAAGCTACTGATAGAAACCGACGCGCCGTATCTGTTGCCTC
GCGATCTTACGCCGAAACCAACGTCACGACGCAACGAGCCCGCGTATCTGCCTCACATCCTGGAGCGCATTGCGCTATGG
CGTGGTGAAGATCCGCAATGGTTAGCGGCGATGACAGATGCCAACGCCAGAACCTTATTTGAGGTCGTATTCTGA

Upstream 100 bases:

>100_bases
TCGGTAAGCGACGGACGCGCGACGAAGATAACGAGGCCGAAACCGAAAAGGCCGAGCACACTGAAGACTAAACACAACCG
CCCGCCAGGGCGGTTGTCAT

Downstream 100 bases:

>100_bases
ACGATCGCTAAATCTTGCGAAAACCGGTGTTTTTTACGCTCTGCTTCACTTCTTTATTGAGTAAATTAAGCAGTAACATC
GAACGCGTTTCGCCATCCGG

Product: DNase TatD

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MGASMFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCWSTAGVHPHDSSQWSSASEDA
IIALANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQIAAELQMPIFMHCRDAHERFLALLDPWLDSLPGAILHCFTG
SRQQMQACVDRGLYIGITGWVCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALW
RGEDPQWLAAMTDANARTLFEVVF

Sequences:

>Translated_264_residues
MGASMFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCWSTAGVHPHDSSQWSSASEDA
IIALANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQIAAELQMPIFMHCRDAHERFLALLDPWLDSLPGAILHCFTG
SRQQMQACVDRGLYIGITGWVCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALW
RGEDPQWLAAMTDANARTLFEVVF
>Mature_263_residues
GASMFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCWSTAGVHPHDSSQWSSASEDAI
IALANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQIAAELQMPIFMHCRDAHERFLALLDPWLDSLPGAILHCFTGS
RQQMQACVDRGLYIGITGWVCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALWR
GEDPQWLAAMTDANARTLFEVVF

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=292, Percent_Identity=33.9041095890411, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI225903439, Length=249, Percent_Identity=33.7349397590361, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI225903424, Length=182, Percent_Identity=34.6153846153846, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI110349730, Length=272, Percent_Identity=27.2058823529412, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226061853, Length=276, Percent_Identity=27.1739130434783, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI110349734, Length=272, Percent_Identity=27.5735294117647, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=27.0742358078603, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI226061614, Length=264, Percent_Identity=25, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=81.9230769230769, Blast_Score=456, Evalue=1e-130,
Organism=Escherichia coli, GI1787342, Length=251, Percent_Identity=33.0677290836653, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082439, Length=248, Percent_Identity=29.0322580645161, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=37.5, Blast_Score=200, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=24.3445692883895, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=168, Percent_Identity=31.547619047619, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17543026, Length=171, Percent_Identity=28.0701754385965, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=37.1024734982332, Blast_Score=180, Evalue=7e-46,
Organism=Drosophila melanogaster, GI221330018, Length=301, Percent_Identity=29.9003322259136, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24586117, Length=268, Percent_Identity=30.2238805970149, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29598; Mature: 29467

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASMFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCW
CCCCEEEECCCCCHHHHHCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCC
STAGVHPHDSSQWSSASEDAIIALANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQI
CCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
AAELQMPIFMHCRDAHERFLALLDPWLDSLPGAILHCFTGSRQQMQACVDRGLYIGITGW
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHCCCHHHHHHHHHCCEEEEEEEE
VCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALW
EECCCCCCCHHHHHCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RGEDPQWLAAMTDANARTLFEVVF
CCCCCCEEEEECCCCHHHHHHCCC
>Mature Secondary Structure 
GASMFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCW
CCCEEEECCCCCHHHHHCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCC
STAGVHPHDSSQWSSASEDAIIALANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQI
CCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
AAELQMPIFMHCRDAHERFLALLDPWLDSLPGAILHCFTGSRQQMQACVDRGLYIGITGW
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHCCCHHHHHHHHHCCEEEEEEEE
VCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALW
EECCCCCCCHHHHHCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RGEDPQWLAAMTDANARTLFEVVF
CCCCCCEEEEECCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]