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The map label for this gene is trpS [H]

Identifier: 194736192

GI number: 194736192

Start: 4624927

End: 4625940

Strand: Reverse

Name: trpS [H]

Synonym: SeSA_A4762

Alternate gene names: 194736192

Gene position: 4625940-4624927 (Counterclockwise)

Preceding gene: 194734115

Following gene: 194735876

Centisome position: 98.23

GC content: 53.06

Gene sequence:

>1014_bases
ATGAACACTCTTCCCATCATTCTGACTGGCGATCGCCCCACCGGCTCGCTGCACCTCGGCCATTATGTCGGTTCACTGCG
CCAGCGCGTCGCGCTACAGCAGGATCACCAACAGTATGTCCTGATTGCCGACCTGCAGGGACTCACCGATAACGGCAGTA
ATCCGCAAAAAATCCGCGATAATATTCCGCAAGTGTTAGCTGACTATCTGGCCGTCGGCATCGATCCCGCGCTAACGACG
ATCTGCCTGCAATCCGCATTACCTGCCCTCGCCGAATTAACGGTGCTGTATATGAATATCGTTACCGTCGCCCGAGTGGA
GCGTAATCCTACGGTAAAAAATGAGATTGCCCAAAAAGGCTTTACCCGTTCCCTGCCGGTCGGGTTCATGGCGTATCCCA
TTAGCCAGGCGGCAGATATCACCGCCTTTAAGGCCGAAATGGTACCGGTTGGCGACGACCAATTGCCCATGATTGAGCAA
ACGAATGAGATCGTTCATAAGATGAATAGTCTTTTCTCCTCGCCGGTATTGCGACCCTGTCAGGCGCTCCTGAGCGATAC
GGGCCGTCTGCCCGGCATTGACGGCAGCGCCAAGATGTCGAAATCGCTCGGCAATACCCTGCTTCTTTCCGCCAGCGAAG
AGACCATCCACCGTGCGGTCAGCGCGATGTACACCGATCCCAATCATTTAAAAATTAGCGATCCGGGAAAAATAGAAGGT
AACGTCGTCTTTACGTGGCTGGATGCGTTCCATCCGGATAAAGCCAAAGTCGCGGCGATGAAAGTACATTATCAACAAGG
CGGATTAGGCGATCGTGTCTGTAAAAATGAGCTGGAGACCTGCCTGCAAGAACTGATCGCGCCAATACGCGAACGGCGGG
CAACCTTTATTGCGGATAAGGGAATGCTAATGGAATTGCTGAAAAAAGGTAGCGAGCGGGCGCATGAGGTCACTCAAAAG
ACGCTACAGGAAGTAAAACGTGGACTGGGTCTGCCCACGCTATTCCAGGTATAA

Upstream 100 bases:

>100_bases
GGCGGCACGGATTACTATCCCTCTTTAAGTAGCCGCCGAAAGGCGGCTACTGTGTTTCGGGACGTCTTTCGGCTTTACAG
TAAGCATAAAGGAGTCCTTA

Downstream 100 bases:

>100_bases
TCAGGCATCAACGTTGTCCAGCGGCCATGACTCAAACAGATAGCCATCAAAGTAGATGTCATCAACATTGGAAAACTCCA
GCAGACGCTGCTTCACGTTT

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRDNIPQVLADYLAVGIDPALTT
ICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKGFTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQ
TNEIVHKMNSLFSSPVLRPCQALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
NVVFTWLDAFHPDKAKVAAMKVHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADKGMLMELLKKGSERAHEVTQK
TLQEVKRGLGLPTLFQV

Sequences:

>Translated_337_residues
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRDNIPQVLADYLAVGIDPALTT
ICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKGFTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQ
TNEIVHKMNSLFSSPVLRPCQALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
NVVFTWLDAFHPDKAKVAAMKVHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADKGMLMELLKKGSERAHEVTQK
TLQEVKRGLGLPTLFQV
>Mature_337_residues
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRDNIPQVLADYLAVGIDPALTT
ICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKGFTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQ
TNEIVHKMNSLFSSPVLRPCQALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
NVVFTWLDAFHPDKAKVAAMKVHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADKGMLMELLKKGSERAHEVTQK
TLQEVKRGLGLPTLFQV

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=27.9279279279279, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI41352700, Length=167, Percent_Identity=29.940119760479, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789786, Length=335, Percent_Identity=25.9701492537313, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71982800, Length=341, Percent_Identity=26.099706744868, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=26.099706744868, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320474, Length=351, Percent_Identity=25.3561253561254, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24666151, Length=336, Percent_Identity=31.547619047619, Blast_Score=134, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36954; Mature: 36954

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRD
CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHH
NIPQVLADYLAVGIDPALTTICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
FTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQTNEIVHKMNSLFSSPVLRPC
CCCCCCCCHHHHCCCHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
QALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
HHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCC
NVVFTWLDAFHPDKAKVAAMKVHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADK
CEEEEEECCCCCCHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMLMELLKKGSERAHEVTQKTLQEVKRGLGLPTLFQV
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHCC
>Mature Secondary Structure
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRD
CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHH
NIPQVLADYLAVGIDPALTTICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
FTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQTNEIVHKMNSLFSSPVLRPC
CCCCCCCCHHHHCCCHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
QALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
HHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCC
NVVFTWLDAFHPDKAKVAAMKVHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADK
CEEEEEECCCCCCHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMLMELLKKGSERAHEVTQKTLQEVKRGLGLPTLFQV
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA