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The map label for this gene is yiaN [H]

Identifier: 194736147

GI number: 194736147

Start: 3736878

End: 3738155

Strand: Direct

Name: yiaN [H]

Synonym: SeSA_A3870

Alternate gene names: 194736147

Gene position: 3736878-3738155 (Clockwise)

Preceding gene: 194735166

Following gene: 194734339

Centisome position: 79.35

GC content: 52.5

Gene sequence:

>1278_bases
ATGGCCGTGGTGATATTTCTCTGCTGCCTGCTCGGCGGGATCGCGATAGGTTTACCCATCGCCTGGTCGCTGCTGCTTTG
CGGCGCTGCTCTGATGGCATACCTGGATATGTTTGACGTGCAGATTATGGCGCAAACCCTGGTTAACGGCGCGGACAGTT
TCTCCCTGCTGGCCATTCCCTTTTTTGTTTTGGCCGGTGAAATCATGAACGCGGGCGGCCTGTCAAAGCGAATTGTCGAC
CTGCCGATGAAGCTGGTCGGCCATAAGCCCGGCGGCCTGGGCTACGTGGGCGTCATTGCGGCAATGATTATGGCCAGCCT
TTCCGGCTCTGCGGTAGCAGATACCGCTGCGGTCGCCGCGCTGCTGGTGCCGATGATGCGCTCCGCAAACTATCCGATCA
ACCGCTCCGTTGGGTTAATCGCTTCCGGCGGGATCATTGCGCCAATTATTCCGCCCTCGATTCCTTTTATTATCTTCGGC
GTTTCCAGCGGCTTGTCGATCAGCAAGCTGTTTATGGCCGGGATCGCACCGGGCATCATGATGGGCGCGGCGCTTATGCT
CACCTGGTGGTGGCAGGCCGGGCGATTAAATCTCCCTTCTCAGCCTAAAGCAACACCGCGTGAAATCTGGCAATCATTGG
TTTCAGGTATCTGGGCGCTGTTTCTACCGGTGATTATTATCGGCGGCTTCCGTTCCGGACTTTTCACGCCAACGGAGGCA
GGGGCGGTCGCCGCGTTTTACGCCCTCTTTGTCGCCGTAGTTATCTATCGGGAATTAACGTTTTCCAGTCTCTACCACGT
GCTGGTCAATGCCGCCAAAACGACGTCAGTCGTCATGTTTCTGGTGGCCGCGGCCCAGGTATCCGCCTGGCTGATTACGA
TCGCGGAATTACCCATGATGGTGTCAGATTTGCTGCAGCCGCTGGTCGACTCTCCGCGACTCTTATTTATCGTCATTATG
ATCTCAATTATGGTCGTCGGTATGGTGATGGACTTAACGCCAACGGTGTTAATTCTTACCCCTGTATTATTGCCATTAGT
TAAAGAAGCCAATATTGATCCGATTTATTTCGGCGTCATGTTCATTATTAACTGCTCTATTGGATTAATCACACCGCCCG
TTGGCAACGTCCTCAACGTTATTTCCGGGGTAGCAAAATTGAAATTTGATGACGCGGTAAGAGGCGTATTCCCTTACGTT
GTCGTACTGATGTCGCTGCTGGTTTTATTTATTTTTATTCCCGAGCTAATTATCACACCGCTTAAATGGATTAATTAA

Upstream 100 bases:

>100_bases
TGCCCACAAGCGTTGCCATCGCGTTAATCGAGCTGCGTCGGCTTTATCACTTAATAACGCGTAACGATTCCTTTCAACAA
CCACAGCAAGGAGCCTAATC

Downstream 100 bases:

>100_bases
AGGATAATATTATGAAATTACACGTTATTGCTCGTTCATTATTGATAGCTGGTCTGACGGTTTTCAGCGTGTCGTCTCTG
GCGGCGCAATCTTTACGTTT

Product: 2,3-diketo-l-gulonate trap transporter large permease yian

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MAVVIFLCCLLGGIAIGLPIAWSLLLCGAALMAYLDMFDVQIMAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVD
LPMKLVGHKPGGLGYVGVIAAMIMASLSGSAVADTAAVAALLVPMMRSANYPINRSVGLIASGGIIAPIIPPSIPFIIFG
VSSGLSISKLFMAGIAPGIMMGAALMLTWWWQAGRLNLPSQPKATPREIWQSLVSGIWALFLPVIIIGGFRSGLFTPTEA
GAVAAFYALFVAVVIYRELTFSSLYHVLVNAAKTTSVVMFLVAAAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIM
ISIMVVGMVMDLTPTVLILTPVLLPLVKEANIDPIYFGVMFIINCSIGLITPPVGNVLNVISGVAKLKFDDAVRGVFPYV
VVLMSLLVLFIFIPELIITPLKWIN

Sequences:

>Translated_425_residues
MAVVIFLCCLLGGIAIGLPIAWSLLLCGAALMAYLDMFDVQIMAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVD
LPMKLVGHKPGGLGYVGVIAAMIMASLSGSAVADTAAVAALLVPMMRSANYPINRSVGLIASGGIIAPIIPPSIPFIIFG
VSSGLSISKLFMAGIAPGIMMGAALMLTWWWQAGRLNLPSQPKATPREIWQSLVSGIWALFLPVIIIGGFRSGLFTPTEA
GAVAAFYALFVAVVIYRELTFSSLYHVLVNAAKTTSVVMFLVAAAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIM
ISIMVVGMVMDLTPTVLILTPVLLPLVKEANIDPIYFGVMFIINCSIGLITPPVGNVLNVISGVAKLKFDDAVRGVFPYV
VVLMSLLVLFIFIPELIITPLKWIN
>Mature_424_residues
AVVIFLCCLLGGIAIGLPIAWSLLLCGAALMAYLDMFDVQIMAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDL
PMKLVGHKPGGLGYVGVIAAMIMASLSGSAVADTAAVAALLVPMMRSANYPINRSVGLIASGGIIAPIIPPSIPFIIFGV
SSGLSISKLFMAGIAPGIMMGAALMLTWWWQAGRLNLPSQPKATPREIWQSLVSGIWALFLPVIIIGGFRSGLFTPTEAG
AVAAFYALFVAVVIYRELTFSSLYHVLVNAAKTTSVVMFLVAAAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMI
SIMVVGMVMDLTPTVLILTPVLLPLVKEANIDPIYFGVMFIINCSIGLITPPVGNVLNVISGVAKLKFDDAVRGVFPYVV
VLMSLLVLFIFIPELIITPLKWIN

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system yiaMNO involved in the uptake of 2,3- diketo-L-gulonate [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=425, Percent_Identity=90.8235294117647, Blast_Score=693, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM [H]

EC number: NA

Molecular weight: Translated: 45178; Mature: 45046

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCC
>Mature Secondary Structure 
AVVIFLCCLLGGIAIGLPIAWSLLLCGAALMAYLDMFDVQIMAQTLVNGADSFSLLAIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVIAAMIMASLSGSAVADTAAVAA
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LLVPMMRSANYPINRSVGLIASGGIIAPIIPPSIPFIIFGVSSGLSISKLFMAGIAPGIM
HHHHHHHCCCCCCCCCCCEEECCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHH
MGAALMLTWWWQAGRLNLPSQPKATPREIWQSLVSGIWALFLPVIIIGGFRSGLFTPTEA
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GAVAAFYALFVAVVIYRELTFSSLYHVLVNAAKTTSVVMFLVAAAQVSAWLITIAELPMM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSDLLQPLVDSPRLLFIVIMISIMVVGMVMDLTPTVLILTPVLLPLVKEANIDPIYFGVM
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHH
FIINCSIGLITPPVGNVLNVISGVAKLKFDDAVRGVFPYVVVLMSLLVLFIFIPELIITP
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKWIN
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]