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The map label for this gene is xerC [H]

Identifier: 194736121

GI number: 194736121

Start: 4033029

End: 4033931

Strand: Direct

Name: xerC [H]

Synonym: SeSA_A4159

Alternate gene names: 194736121

Gene position: 4033029-4033931 (Clockwise)

Preceding gene: 194735552

Following gene: 194734329

Centisome position: 85.64

GC content: 56.15

Gene sequence:

>903_bases
ATGACGGATGTCGCGCTTTCTCTGGATGTCTCGCGGTTCCTGCGCTATTTAGGCGTGGAGCGCCAGCTTAGCCCCATTAC
CCTGCAGAACTACCAGCGTCAGCTTGATGCCATTATCGCTTTAGCCGGAGAAACCGGGCTGAAAAGCTGGCAACAATGTG
ACGCTGCGATTGTGCGCAGTTTTGCGGTGCGCAGTCGGCGTAAAGGGCTTGGCCCTGCCAGTCTGGCGCTACGTCTCTCG
GCATTGCGAAGCTTTTTTGACTGGTTAGTCAGTCAGGGCGAATTGAAAGCTAACCCGGCGAAGGGTGTCTCCGCACCGAA
AGCGCCGCGTCATCTGCCGAAAAATATTGATGTCGACGACGTTAACCGCCTGCTGGACATAGATCTTAACGATCCGCTCG
CCGTACGTGATCGGGCGATGCTGGAGGTCATGTACGGCGCGGGACTGCGTTTATCCGAACTGGTTGGCCTGGATATAAAG
CACCTCGATCTCGATACCGGCGAAGTGTGGGTAATGGGTAAAGGCAGCAAAGAGCGACGCCTGCCGATTGGCCGTAACGC
GGTGACGTGGATTGAGCACTGGCTGGATCTGCGCGGACTGTTCGCCAGCGATGAAGAGGCGTTATTCCTGTCGAAGCTCG
GCAAGCGTATCTCCGCGCGCAATGTCCAAAAACGGTTCGCCGAATGGGGCATAAAGCAGGGGCTAAACAGCCACGTGCAT
CCACATAAGCTGCGCCATTCGTTCGCGACCCATATGCTGGAATCGAGCGGCGATCTGCGCGGCGTGCAAGAGCTGCTGGG
TCATGCCAACCTTTCCACCACCCAAATTTATACTCATCTTGATTTTCAACATCTTGCTTCAGTGTACGACGCGGCGCATC
CGCGCGCTAAACGGGGGAAATAA

Upstream 100 bases:

>100_bases
GCCGTGACCCGCACCACTATCAGCCTGGGCAGGGGACGCAGCTTTTACAGGAGATCGCGCTGATGCTGCCGGAACTGCTG
GAACGCTGGATTAAACGCGT

Downstream 100 bases:

>100_bases
TGCGTTTTTACCGGCCTTTGGGGCGTATTGCCGCGCTCACCTTTGACCTGGATGATACCCTTTATGATAACCGTCCGGTG
ATTTTGCGTACTGAGCAGGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTDVALSLDVSRFLRYLGVERQLSPITLQNYQRQLDAIIALAGETGLKSWQQCDAAIVRSFAVRSRRKGLGPASLALRLS
ALRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIK
HLDLDTGEVWVMGKGSKERRLPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK

Sequences:

>Translated_300_residues
MTDVALSLDVSRFLRYLGVERQLSPITLQNYQRQLDAIIALAGETGLKSWQQCDAAIVRSFAVRSRRKGLGPASLALRLS
ALRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIK
HLDLDTGEVWVMGKGSKERRLPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
>Mature_299_residues
TDVALSLDVSRFLRYLGVERQLSPITLQNYQRQLDAIIALAGETGLKSWQQCDAAIVRSFAVRSRRKGLGPASLALRLSA
LRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIKH
LDLDTGEVWVMGKGSKERRLPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVHP
HKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region, forming

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=300, Percent_Identity=89.6666666666667, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=37.6271186440678, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1790768, Length=167, Percent_Identity=29.3413173652695, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33600; Mature: 33469

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVALSLDVSRFLRYLGVERQLSPITLQNYQRQLDAIIALAGETGLKSWQQCDAAIVRS
CCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FAVRSRRKGLGPASLALRLSALRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLDTGEVWVMGKGSKERR
HHHEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCEEEEECCCCCCC
LPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHEECCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDVALSLDVSRFLRYLGVERQLSPITLQNYQRQLDAIIALAGETGLKSWQQCDAAIVRS
CCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FAVRSRRKGLGPASLALRLSALRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLDTGEVWVMGKGSKERR
HHHEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCEEEEECCCCCCC
LPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHEECCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]