Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 194735718

GI number: 194735718

Start: 2715098

End: 2715616

Strand: Reverse

Name: tadA [H]

Synonym: SeSA_A2811

Alternate gene names: 194735718

Gene position: 2715616-2715098 (Counterclockwise)

Preceding gene: 194734731

Following gene: 194736632

Centisome position: 57.67

GC content: 56.84

Gene sequence:

>519_bases
TTGTCTGATGTCGAATTAGATCACGAATACTGGATGCGCCACGCGCTGACGCTGGCGAAACGCGCCTGGGACGAACGCGA
GGTTCCGGTTGGCGCGGTATTGGTGCATAACCATCGTGTCATTGGCGAAGGCTGGAACCGACCCATTGGCCGCCACGATC
CTACTGCGCATGCTGAAATAATGGCGCTGCGTCAGGGAGGTCTGGTATTGCAGAATTACCGGTTACTGGATACCACGCTG
TATGTCACGCTGGAACCCTGTGTGATGTGCGCAGGCGCTATGGTGCATAGCCGCATTGGACGCGTTGTCTTTGGCGCGCG
CGATGCAAAAACCGGCGCGGCCGGATCGCTAATTGATGTGCTGCACCATCCGGGAATGAATCACCGGGTCGACATTATTG
AAGGGGTGCTGCGCGATGAATGTGCGACGCTGCTCAGTGATTTTTTCCGTATGCGTCGTCAGGAAATTAAAGCCCTGAAG
AAAGCCGACCGTGCGCAAGGCGCGGGGCCGACAGTATAG

Upstream 100 bases:

>100_bases
CTGGCGGGTGACGCCGCACGGCGAGCTGCAGCAGCTCGAATAGTGAAACGCATAGCGTCTGTGTATAATGCCGCCCGCTT
TCATTACCGGAGTTATCTCT

Downstream 100 bases:

>100_bases
CGCAATGCCGGATAAGAGGTTACGCGTCGCCATCCGATAAGACCATCACGCTATTTTTCTTCTTTCTTCTGCGGCGTAAA
CAGTAAAGACGGCGAATGCG

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVLQNYRLLDTTL
YVTLEPCVMCAGAMVHSRIGRVVFGARDAKTGAAGSLIDVLHHPGMNHRVDIIEGVLRDECATLLSDFFRMRRQEIKALK
KADRAQGAGPTV

Sequences:

>Translated_172_residues
MSDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVLQNYRLLDTTL
YVTLEPCVMCAGAMVHSRIGRVVFGARDAKTGAAGSLIDVLHHPGMNHRVDIIEGVLRDECATLLSDFFRMRRQEIKALK
KADRAQGAGPTV
>Mature_171_residues
SDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVLQNYRLLDTTLY
VTLEPCVMCAGAMVHSRIGRVVFGARDAKTGAAGSLIDVLHHPGMNHRVDIIEGVLRDECATLLSDFFRMRRQEIKALKK
ADRAQGAGPTV

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=153, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI19923945, Length=68, Percent_Identity=47.0588235294118, Blast_Score=64, Evalue=6e-11,
Organism=Escherichia coli, GI145693172, Length=165, Percent_Identity=89.0909090909091, Blast_Score=313, Evalue=5e-87,
Organism=Escherichia coli, GI1786616, Length=156, Percent_Identity=30.7692307692308, Blast_Score=61, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17541138, Length=155, Percent_Identity=36.7741935483871, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=38.1443298969072, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=173, Percent_Identity=35.2601156069364, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=33.5616438356164, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19219; Mature: 19088

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPIGRHDPTAHAEI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEECCCCCCCCCCCCCCHHHHH
MALRQGGLVLQNYRLLDTTLYVTLEPCVMCAGAMVHSRIGRVVFGARDAKTGAAGSLIDV
HHHHCCCEEEECCEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
LHHPGMNHRVDIIEGVLRDECATLLSDFFRMRRQEIKALKKADRAQGAGPTV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SDVELDHEYWMRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPIGRHDPTAHAEI
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEECCCCCCCCCCCCCCHHHHH
MALRQGGLVLQNYRLLDTTLYVTLEPCVMCAGAMVHSRIGRVVFGARDAKTGAAGSLIDV
HHHHCCCEEEECCEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
LHHPGMNHRVDIIEGVLRDECATLLSDFFRMRRQEIKALKKADRAQGAGPTV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]