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The map label for this gene is hflX [H]

Identifier: 194735629

GI number: 194735629

Start: 4504238

End: 4505518

Strand: Direct

Name: hflX [H]

Synonym: SeSA_A4630

Alternate gene names: 194735629

Gene position: 4504238-4505518 (Clockwise)

Preceding gene: 194736692

Following gene: 194735493

Centisome position: 95.65

GC content: 54.1

Gene sequence:

>1281_bases
TTGTTTGACCGTTATGATGCCGGTGAGCAGGCGGTACTGGTACACATCTATTTTTCGCAAGACAAAGATATGGAAGACCT
CCAGGAGTTTGAATCTCTGGTCTCTTCCGCCGGTGTCGAAGCAATGCAGGTGATTACCGGTAGCCGTAAAGCACCGCACC
CGAAGTACTTTGTAGGTGAAGGTAAGGCAGTTGAAATTGCGGAAGCCGTGAAAGCGACTGGCGCAGCGGTCGTATTGTTT
GATCATGCATTGAGTCCAGCCCAGGAGCGAAACCTGGAGCGTTTGTGCGAGTGCCGGGTTATCGATCGCACCGGTCTTAT
CTTAGATATTTTTGCCCAACGTGCGCGTACCCATGAAGGTAAGTTGCAGGTTGAGCTGGCGCAGCTACGCCATCTGGCTA
CGCGTCTGGTGCGTGGCTGGACCCACCTTGAACGTCAGAAAGGCGGGATTGGTTTGCGCGGTCCGGGTGAAACCCAGCTC
GAAACCGACCGTCGTTTACTGCGTAATCGCATTGTGCAGATTCAGTCGCGCCTGGAGAAAGTTGAGAAGCAACGTGAGCA
GGGGCGGCAGTCGCGCATCAAGGCCGACGTTCCGACGGTATCGCTGGTGGGCTATACCAACGCCGGAAAATCCACCCTTT
TTAATCAGATCACTGAAGCGCGGGTCTATGCGGCAGATCAGCTATTTGCGACGCTGGACCCCACGTTACGTCGTATTGAT
GTAGCGGATGTCGGTGAAACCGTTCTGGCGGATACGGTAGGCTTTATCCGCCATTTACCGCACGATCTGGTGGCTGCCTT
TAAAGCTACCCTGCAGGAGACGCGTCAGGCGACGCTGCTGCTGCATGTGGTCGATGCGGCGGATGTTCGTGTGCAGGAAA
ACATCGAGGCGGTAAACACCGTTCTTGAAGAGATTGACGCTCACGAAATCCCCACCTTAATGGTGATGAACAAAATCGAT
ATGCTGGACGACTTTGAACCGCGTATCGACAGAGATGAAGAGAATAAACCCATCCGCGTTTGGCTTTCAGCGCAAAGCGG
CGTGGGAATACCACAGCTTTTTCAGGCTTTGACGGAGCGTCTTTCCGGCGAGGTGGCGCAGCATACGCTGCGTTTGCCGC
CGCAGGAAGGGCGTCTGAGAAGCCGGTTTTATCAGCTTCAGGCAATAGAAAAAGAGTGGATGGAGGAAGACGGTAGCGTC
AGTCTGCAGGTACGAATGCCGATTGTCGACTGGCGTCGCCTCTGTAAACAAGAACCGGCGTTGATCGAATACGTGATCTA
G

Upstream 100 bases:

>100_bases
CGCAACAGGACAGCGAAGAGACTGAATAAGTTCACGCGCTGTTTATCCATGTCGGGGGCGTCGGATAATCGCCCCCGCTG
GTTATTAAGAGGGTTTACGC

Downstream 100 bases:

>100_bases
ACGCGAAGTCATTCAGGTCGTATTGAGGCGGTAGCTGAGAGAATCTCAGGAGCTCACAACGAAGTGACCTGGGGTAAAAA
AGCCGCCACTCAAGACGCAG

Product: putative GTPase HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFESLVSSAGVEAMQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGAAVVLF
DHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRNRIVQIQSRLEKVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNQITEARVYAADQLFATLDPTLRRID
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVVDAADVRVQENIEAVNTVLEEIDAHEIPTLMVMNKID
MLDDFEPRIDRDEENKPIRVWLSAQSGVGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV
SLQVRMPIVDWRRLCKQEPALIEYVI

Sequences:

>Translated_426_residues
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFESLVSSAGVEAMQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGAAVVLF
DHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRNRIVQIQSRLEKVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNQITEARVYAADQLFATLDPTLRRID
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVVDAADVRVQENIEAVNTVLEEIDAHEIPTLMVMNKID
MLDDFEPRIDRDEENKPIRVWLSAQSGVGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV
SLQVRMPIVDWRRLCKQEPALIEYVI
>Mature_426_residues
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFESLVSSAGVEAMQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGAAVVLF
DHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRNRIVQIQSRLEKVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNQITEARVYAADQLFATLDPTLRRID
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVVDAADVRVQENIEAVNTVLEEIDAHEIPTLMVMNKID
MLDDFEPRIDRDEENKPIRVWLSAQSGVGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV
SLQVRMPIVDWRRLCKQEPALIEYVI

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=286, Percent_Identity=30.4195804195804, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI310133116, Length=280, Percent_Identity=29.6428571428571, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI310124269, Length=262, Percent_Identity=29.7709923664122, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI310124267, Length=262, Percent_Identity=29.7709923664122, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI310124171, Length=262, Percent_Identity=29.7709923664122, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI310124169, Length=262, Percent_Identity=29.7709923664122, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1790615, Length=426, Percent_Identity=96.9483568075117, Blast_Score=848, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561038, Length=296, Percent_Identity=28.7162162162162, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24650079, Length=284, Percent_Identity=31.6901408450704, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48263; Mature: 48263

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFESLVSSAGVEAMQVITGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECC
GKAVEIAEAVKATGAAVVLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEG
CCEEHHHHHHHHCCCEEEEEECCCCCHHHHCHHHHHHHEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRNRIVQIQSRLEK
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNQITEARVYAADQLFATLDPTLRRID
HHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVVDAADVRVQENIEAVNT
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHH
VLEEIDAHEIPTLMVMNKIDMLDDFEPRIDRDEENKPIRVWLSAQSGVGIPQLFQALTER
HHHHHCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
LSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSVSLQVRMPIVDWRRLCKQEPA
HCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCC
LIEYVI
CEEECC
>Mature Secondary Structure
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFESLVSSAGVEAMQVITGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECC
GKAVEIAEAVKATGAAVVLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEG
CCEEHHHHHHHHCCCEEEEEECCCCCHHHHCHHHHHHHEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRNRIVQIQSRLEK
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNQITEARVYAADQLFATLDPTLRRID
HHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVVDAADVRVQENIEAVNT
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHH
VLEEIDAHEIPTLMVMNKIDMLDDFEPRIDRDEENKPIRVWLSAQSGVGIPQLFQALTER
HHHHHCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
LSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSVSLQVRMPIVDWRRLCKQEPA
HCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCC
LIEYVI
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]