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The map label for this gene is rbsK [H]

Identifier: 194735486

GI number: 194735486

Start: 3600319

End: 3601533

Strand: Direct

Name: rbsK [H]

Synonym: SeSA_A3738

Alternate gene names: 194735486

Gene position: 3600319-3601533 (Clockwise)

Preceding gene: 194738126

Following gene: 194735820

Centisome position: 76.45

GC content: 41.56

Gene sequence:

>1215_bases
ATGAAATTTGAACGCCATCATAGAATATTGAAGGAACTCAGTATTTCGGGAGTTGTAAAAGTTTCAAATCTGGCGAAAAG
TCTCAAGGTAACAAAGGAAACTATTCGTTCAGATCTCAATGAACTTGCCGGACAGGGATATCTTACTCGCTGTCATGGTG
GTGCATTTATTACCCTTGATTCTCTTGATAACGTCGCAAAAAATGAAATTGCTTATGTGCTGGAAAAATATGAATCAGCG
CAGAAAAATAAAAAAGGTCTCTCTGCCATGAAAAATAATGTATGTGTTATTGGCTCGTTCAATGTTGATATTATCAGTTA
TCTACCGAGATTACCCTCAACGGGAGAATCATTGCTGGCCGATAAATTTATTTTTTCACCCGGCGGTAAGGGATGTAATC
AGGCATTAGCAGCAAGCTATGCCGACTCTGATGTGCATTTTATTACTAAAGTCGGCTCAGACCATTTTAGTGATTACGCC
ATTAATTTTATAAACTCATCAAAAATCCATAAAAGTGTTATCTACCAGACCAAAGAAACACAAACAGGTACAGCAACCAT
CATGGTGAATGGAGATACCGGAGATAACGTCATCGCTATCTACCCTGGCGCCAACATGACAATTTCCCCTGATGAAATCA
CCATTCAGAAAGAAGCCATTATTCATTCAGATATTGTTCTTGTCCAACTGGAGACGAATTACGAAGCGCTGCAGCAAACA
ATTCGTCTCGCACAAAAAAATGACATACCGGTCATCATCAATCCAGCGCCATACAATGACATGGTTAACACCATCATTGA
TAACATTGACTATATTACGCCAAATGAAACGGAAGCAGGCCTGCTGGCCAATATGGCGGTTAATGATATCGAATCAGCCA
AATGCGCGGCCAAAATTATTCATCAGAAAGGCGTCAAAAATACCATTATTACATTAGGTAGCAAAGGTTCGCTTGCTTAT
GATGGCACACAATTCATCTATTCCCCGGCATTTCCGGCAGTTGTAAAAAATACGGCGGGAGCGGGTGACGCTTTCAATGG
CGCCCTCGCATCTGGTCTTGCAAAAGGAAAGTCACTGGCATCCGCATTGTGCTACGCCAGCGCATTTGCCTCACTTGCGG
TTGAAACGCCTAATGCCTCTGATATGCCGGAAAACGACTCCGTTCTTCATCGTATTCAGGGTTCACATTACAAACAAACT
ATCTCTACTCACTAA

Upstream 100 bases:

>100_bases
ATTACATTTTTGTTTTTTTTTGGTTTCTGCCATCACTTTATGGTGACAATCACAACAATATACTTCTCCCGGGACTAATT
TAACCACGGTGAGGTAAAAA

Downstream 100 bases:

>100_bases
ATCAAGGAGCAGACTATGAACAATACGCAGAAAAAACTAAAGGTGCTCTTTATTGGAGAATCCTGGCATATTCATATGAT
TCATTCAAAAGGTTATGACA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLDSLDNVAKNEIAYVLEKYESA
QKNKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYA
INFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIIHSDIVLVQLETNYEALQQT
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAY
DGTQFIYSPAFPAVVKNTAGAGDAFNGALASGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQT
ISTH

Sequences:

>Translated_404_residues
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLDSLDNVAKNEIAYVLEKYESA
QKNKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYA
INFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIIHSDIVLVQLETNYEALQQT
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAY
DGTQFIYSPAFPAVVKNTAGAGDAFNGALASGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQT
ISTH
>Mature_404_residues
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLDSLDNVAKNEIAYVLEKYESA
QKNKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYA
INFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIIHSDIVLVQLETNYEALQQT
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAY
DGTQFIYSPAFPAVVKNTAGAGDAFNGALASGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQT
ISTH

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=262, Percent_Identity=33.206106870229, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1790193, Length=272, Percent_Identity=36.0294117647059, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1788491, Length=308, Percent_Identity=26.2987012987013, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082343, Length=299, Percent_Identity=25.0836120401338, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788017, Length=258, Percent_Identity=25.1937984496124, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788484, Length=311, Percent_Identity=22.508038585209, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=305, Percent_Identity=33.4426229508197, Blast_Score=141, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319884, Length=323, Percent_Identity=28.1733746130031, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20128807, Length=298, Percent_Identity=33.8926174496644, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24583886, Length=278, Percent_Identity=28.4172661870504, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 43482; Mature: 43482

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS51000 HTH_DEOR_2 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLD
CCCHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEC
SLDNVAKNEIAYVLEKYESAQKNKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCCCCCHHHHH
DKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYAINFINSSKIHKSVIYQTKET
HHHEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHEECCCC
QTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIIHSDIVLVQLETNYEALQQT
CCCEEEEEEECCCCCCEEEEECCCCCEECCCCEEEEHHHEEECCEEEEEEECCHHHHHHH
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKII
HHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HQKGVKNTIITLGSKGSLAYDGTQFIYSPAFPAVVKNTAGAGDAFNGALASGLAKGKSLA
HHCCCCCEEEEECCCCCEEECCCEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
SALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQTISTH
HHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLD
CCCHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEC
SLDNVAKNEIAYVLEKYESAQKNKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCCCCCHHHHH
DKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYAINFINSSKIHKSVIYQTKET
HHHEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHEECCCC
QTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIIHSDIVLVQLETNYEALQQT
CCCEEEEEEECCCCCCEEEEECCCCCEECCCCEEEEHHHEEECCEEEEEEECCHHHHHHH
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKII
HHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HQKGVKNTIITLGSKGSLAYDGTQFIYSPAFPAVVKNTAGAGDAFNGALASGLAKGKSLA
HHCCCCCEEEEECCCCCEEECCCEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
SALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQTISTH
HHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]