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The map label for this gene is exuT [H]

Identifier: 194735475

GI number: 194735475

Start: 1585768

End: 1587054

Strand: Reverse

Name: exuT [H]

Synonym: SeSA_A1647

Alternate gene names: 194735475

Gene position: 1587054-1585768 (Counterclockwise)

Preceding gene: 194735348

Following gene: 194735244

Centisome position: 33.7

GC content: 46.46

Gene sequence:

>1287_bases
ATGAAAAGAAAAACAATGGGATGGCTTATCGTTTTTCTTCTATTTATAGTTTACATGCTCAACTATATGGATCGTTCAGC
ATTGTCGATAACTGCCCCCTTGATCGAAAAGGAGTTAGGATTTAACGCCGCGGAGATGGGAATGATCTTCAGCGCATTTT
TTATCGGATACGCCCTGTTTAATTTTATTGGTGGCTGGGCCAGCGATAAAGTTGGGCCAAAAACGGTTTTTCTCATCGCA
GCGTTACTATGGTCTGTATTTTGTGGCTTAACTGGTTTAGTCACCGGATTGTGGACAATGCTTATCGTGCGCGTTCTTTT
CGGTATGGCTGAAGGACCGGTCAGCGCTGCCGGAAATAAAATCATCAATAACTGGATTTCCCGAAAGGAGTCTGCCACGG
CGATCGGAATTTTTAGCGCCGGTTCCCCGCTCGGCGGCGCGGTGTCCGGGCCGATAGTGGGCCTGCTGGCGTTATCCTTA
GGCTGGCGCCCCGCATTTGGCATTATTTTCTTATTTGGCCTGGCCTGGGTACTGCTCTGGTACTTTATCGTTAGCGATAA
GCCAACAATGAGTAAACGCCTGGCGCCGGAAGAACGCATTGATTTTGAAAATCATGAGGACGTTATTTTATCTGATGATG
GCCGGGCTACGCCTTCACTCGGCTATTACATGAAACAACCAATGGTATGGGCGACAACTCTGGCTTTTTTCAGCTATAAC
TATATTCTTTTTTTCTTCCTGACCTGGTTCCCAAGTTACCTGAACCATTCGTTACATCTCGATATTAAAGAAATTAGTAT
CGCCACGGTAATTCCCTGGGTCATCGGCGCCATTGGTATGGTGCTCGGCGGCGTCTGTTCTGATGTAATTTATCGGATTA
CCGGTAATGCTCTGCTCTCACGTCGACTTATTCTGGGCGTATGTCTGGCAGGCGCAGCGGTATGTGTTGCCGTTTCCGGT
ACTGTTAGCACTATTGGTAGCGCAATTACGCTCATGTCAGTTTCACTCTTCCTGCTCTATTTAACGGGCCCAATTTATTG
GGCGGTTATTCAGGATGTTGTTCATAAAGATAAGGTAGGGAGCGTCGGCGGAGCCATGCATGGCCTGGCTAATATATCCG
GTATTATCGGTCCGCTTGTCACCGGTTTTATCGTTCAATTTAGCGGTAAATATGACTATGCGTTCTATCTGGCTGGTGCT
ATCGCTATCGTTTCAAGCCTGTTGGTCTTCGTGTTTGTAAAAAGTAAAGGATTCAAAGCCAATGAAAGTCAAAGCTGTGT
TCATTAA

Upstream 100 bases:

>100_bases
TTTTGTTATATTGATCACGTTCTAACCACAAGAGAGGTGATTTGAAAATAACCTTAAAATATTGTGGTCAGGCCGCTAGA
CCACAATAAGAGGATTAATC

Downstream 100 bases:

>100_bases
TAAGCCTGGTGAAGTTGAAACCCGCTGGGTGGATTATCCCCATAAGAAAGAAAATGAAGTATTAATTAAGGTTGATGCTG
CAGGCATTTGCGGATCGGAT

Product: membrane transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKRKTMGWLIVFLLFIVYMLNYMDRSALSITAPLIEKELGFNAAEMGMIFSAFFIGYALFNFIGGWASDKVGPKTVFLIA
ALLWSVFCGLTGLVTGLWTMLIVRVLFGMAEGPVSAAGNKIINNWISRKESATAIGIFSAGSPLGGAVSGPIVGLLALSL
GWRPAFGIIFLFGLAWVLLWYFIVSDKPTMSKRLAPEERIDFENHEDVILSDDGRATPSLGYYMKQPMVWATTLAFFSYN
YILFFFLTWFPSYLNHSLHLDIKEISIATVIPWVIGAIGMVLGGVCSDVIYRITGNALLSRRLILGVCLAGAAVCVAVSG
TVSTIGSAITLMSVSLFLLYLTGPIYWAVIQDVVHKDKVGSVGGAMHGLANISGIIGPLVTGFIVQFSGKYDYAFYLAGA
IAIVSSLLVFVFVKSKGFKANESQSCVH

Sequences:

>Translated_428_residues
MKRKTMGWLIVFLLFIVYMLNYMDRSALSITAPLIEKELGFNAAEMGMIFSAFFIGYALFNFIGGWASDKVGPKTVFLIA
ALLWSVFCGLTGLVTGLWTMLIVRVLFGMAEGPVSAAGNKIINNWISRKESATAIGIFSAGSPLGGAVSGPIVGLLALSL
GWRPAFGIIFLFGLAWVLLWYFIVSDKPTMSKRLAPEERIDFENHEDVILSDDGRATPSLGYYMKQPMVWATTLAFFSYN
YILFFFLTWFPSYLNHSLHLDIKEISIATVIPWVIGAIGMVLGGVCSDVIYRITGNALLSRRLILGVCLAGAAVCVAVSG
TVSTIGSAITLMSVSLFLLYLTGPIYWAVIQDVVHKDKVGSVGGAMHGLANISGIIGPLVTGFIVQFSGKYDYAFYLAGA
IAIVSSLLVFVFVKSKGFKANESQSCVH
>Mature_428_residues
MKRKTMGWLIVFLLFIVYMLNYMDRSALSITAPLIEKELGFNAAEMGMIFSAFFIGYALFNFIGGWASDKVGPKTVFLIA
ALLWSVFCGLTGLVTGLWTMLIVRVLFGMAEGPVSAAGNKIINNWISRKESATAIGIFSAGSPLGGAVSGPIVGLLALSL
GWRPAFGIIFLFGLAWVLLWYFIVSDKPTMSKRLAPEERIDFENHEDVILSDDGRATPSLGYYMKQPMVWATTLAFFSYN
YILFFFLTWFPSYLNHSLHLDIKEISIATVIPWVIGAIGMVLGGVCSDVIYRITGNALLSRRLILGVCLAGAAVCVAVSG
TVSTIGSAITLMSVSLFLLYLTGPIYWAVIQDVVHKDKVGSVGGAMHGLANISGIIGPLVTGFIVQFSGKYDYAFYLAGA
IAIVSSLLVFVFVKSKGFKANESQSCVH

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=390, Percent_Identity=25.1282051282051, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI154350196, Length=412, Percent_Identity=24.5145631067961, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI9966811, Length=396, Percent_Identity=22.2222222222222, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI9945322, Length=372, Percent_Identity=22.5806451612903, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI21322234, Length=421, Percent_Identity=23.0403800475059, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI5031955, Length=265, Percent_Identity=26.4150943396226, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI148743791, Length=374, Percent_Identity=22.7272727272727, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4885441, Length=337, Percent_Identity=20.7715133531157, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI2367379, Length=412, Percent_Identity=27.4271844660194, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1789515, Length=424, Percent_Identity=31.1320754716981, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1789152, Length=431, Percent_Identity=28.7703016241299, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI87082320, Length=412, Percent_Identity=26.6990291262136, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI2367193, Length=305, Percent_Identity=26.2295081967213, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082071, Length=427, Percent_Identity=21.7798594847775, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788573, Length=299, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=392, Percent_Identity=23.7244897959184, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17535049, Length=404, Percent_Identity=23.2673267326733, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI193205400, Length=307, Percent_Identity=26.0586319218241, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115533556, Length=384, Percent_Identity=25, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115533554, Length=378, Percent_Identity=24.6031746031746, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32565916, Length=257, Percent_Identity=25.6809338521401, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32565914, Length=308, Percent_Identity=25, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI25141316, Length=384, Percent_Identity=24.21875, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141318, Length=384, Percent_Identity=24.21875, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI86561091, Length=270, Percent_Identity=26.2962962962963, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71991453, Length=420, Percent_Identity=24.047619047619, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71991448, Length=420, Percent_Identity=24.047619047619, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25141341, Length=358, Percent_Identity=24.0223463687151, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=187, Percent_Identity=24.0641711229947, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554962, Length=244, Percent_Identity=24.5901639344262, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569727, Length=336, Percent_Identity=22.0238095238095, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554148, Length=259, Percent_Identity=23.5521235521236, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560030, Length=255, Percent_Identity=23.921568627451, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641682, Length=430, Percent_Identity=25.5813953488372, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24648416, Length=409, Percent_Identity=23.7163814180929, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356189, Length=409, Percent_Identity=23.7163814180929, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24639764, Length=417, Percent_Identity=24.220623501199, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28573299, Length=428, Percent_Identity=22.8971962616822, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920686, Length=406, Percent_Identity=23.6453201970443, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24584153, Length=381, Percent_Identity=22.0472440944882, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655271, Length=431, Percent_Identity=23.8979118329466, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20130135, Length=431, Percent_Identity=23.8979118329466, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45550460, Length=261, Percent_Identity=26.8199233716475, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24655255, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI20130167, Length=455, Percent_Identity=21.3186813186813, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654215, Length=395, Percent_Identity=22.0253164556962, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19922400, Length=395, Percent_Identity=22.0253164556962, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24580790, Length=402, Percent_Identity=22.1393034825871, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550495, Length=406, Percent_Identity=25.3694581280788, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573708, Length=399, Percent_Identity=21.8045112781955, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573707, Length=399, Percent_Identity=21.8045112781955, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583789, Length=275, Percent_Identity=24.7272727272727, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653727, Length=396, Percent_Identity=23.2323232323232, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281361682, Length=392, Percent_Identity=19.6428571428571, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24658658, Length=445, Percent_Identity=23.1460674157303, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24658674, Length=267, Percent_Identity=24.7191011235955, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46434; Mature: 46434

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCC
>Mature Secondary Structure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CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]