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The map label for this gene is uidA [H]

Identifier: 194735430

GI number: 194735430

Start: 3195302

End: 3197113

Strand: Direct

Name: uidA [H]

Synonym: SeSA_A3313

Alternate gene names: 194735430

Gene position: 3195302-3197113 (Clockwise)

Preceding gene: 194737356

Following gene: 194735793

Centisome position: 67.85

GC content: 53.42

Gene sequence:

>1812_bases
ATGTTACGTCCCGTAGAAACCCAGAGCCGCGAAATCAAAAAACTTGATGGACTGTGGTCGTTTTGCACGGATGCAGACGA
TTGCGGTATCGCGCAACAATGGTGGCGACAACCGCTCCCCCAAAGCCGCGCTATCGCCGTACCGGGTAGTTATAACGATC
AGTTTGCCGATGCAGAGATCCGCAACTATGTCGGCAATGTCTGGTATCAGCTCAACGTCCGCATCCCCAAAGGCTGGGAG
CATCAACGCATCGTTCTACGTTTTGATGCCGTCACGCATTATGGAAAGGTATGGGTAAATGACCACGCCGTGATGGAACA
CCAGGGAGGCTATACACCTTTCGAAGCGGATATCAGCCACCTGGCGGCAGCCGGAGAGAGCATACGTATCACAGTATGCG
TCAATAACGAGCTGAGCTGGCAGACTATCCCTCCGGGGGTGGTGACCCGTGATGAAACGGGGAAAAGGCAGCAATCATAC
TTCCATGATTTCTTTAATTACGCCGGTATCCACCGTAGCGTCATGCTCTACACCACACCAAAAACGTTTGTTCAGGATAT
TACGGTGACGACGGAGGTCGCGAACGATCTCTCCCGGGCCACACTGAGCTGGCGGGTGGAGGCCAACGGTGAAGTACGCG
TAGAACTGCGGGATGCCGGGCAGCATATTGTCGCCTACGGCGAAGGGGCAAAGGGCGAATTACAGATAGCAGCGCCACGA
TTATGGCAACCGGGCGAAGGATATCTGTACGAGCTGCGGGTTATCGCACAGCATCAGGACGAACGTGATGACTATCCGCT
TCGGGTAGGAATCCGTAGCGTAGCGGTAAAAGGCGAACAGTTTCTGATAAATCATAAACCTTTTTATTTTACCGGCTTCG
GTCGCCATGAAGATGCCGATCTACGAGGGAAAGGATTTGATAACGTGCTGATGGTACACGATCACGCGCTAATGTCGTGG
ATTGGCGCCAACTCTTATCGCACGTCGCACTATCCTTACGCCGAAGAGATGCTCGACTGGGCGGACGAGCATGGCATTGT
CGTCATTGATGAAACAGCAGCTGTTGGTTTCAATCTCTCTTTAGGTATCGGCTTTGATTCCTGCGAAAAACCGAAGGCGC
TATACAGCGAGGAAGGCGTCAATGATGAAACACAGCGGGCGCATCTCAAGGCTATTCAGGAATTGATCGCCCGCGATAAA
AACCATCCCAGCGTGGTGATGTGGAGTATCGCGAATGAGCCGGATACCCGTCCAGAAGGCGCCAGAGACTATTTTGCGCC
ACTGGCGCAGGCCACGCGCGAACTGGACCCGACCCGCCCTATAACCTGCGTGAACGTCATGTTTTGCGATGTGGAAACCG
ACACCATCACCGACCTCTTCGATGTGGTGTGCCTGAACCGCTATTACGGTTGGTATGTACAAAGCGGCGATCTTGCGAAA
GCAGAAAAAGTGCTGGAGAAAGAGTTACTGGCCTGGCAGGAGAAACTCCACCGCCCCATCATCATGACGGAATATGGTGT
CGATACGCTGGCAGGGCTGCATTCGATGTACAGCGACATGTGGAGCGAAGAGTACCAGTGCGCCTGGCTGGAGATGTATC
ACCGAGTATTCGATCGCGTTAGCGCCGTTGTCGGCGAGCAGGTCTGGAACTTTGCCGATTTCGCGACTTCACAGGGCATT
ATGCGCGTCGGCGGTAATCGAAAAGGGATTTTTACCCGCGACAGAAGACCAAAATCGGCGGCCTTTATACTGCAAAAACG
CTGGACCGGTATGACCTTCGGCGAAAAGCCACAGCAGGGAGAGAAATCATGA

Upstream 100 bases:

>100_bases
CCTCTCGATCGCTGCGTGATAACTATTGCCTCAGACAACTGGTTAACTTGTTTTATTGCTGGTTGACCAATGAAAATTCA
TCAGGATTAAGGAGTGAACA

Downstream 100 bases:

>100_bases
ACCAGCCGCTTTCCTGGCGCGTTATCGTAGGCTACAGCCTGGGTGATGTTGCCAATAATTTCGCCTTCGCCATGGGGGCG
CTGTTCCTGCTAAGTTATTA

Product: beta-D-glucuronidase

Products: NA

Alternate protein names: GUS; Beta-D-glucuronoside glucuronosohydrolase [H]

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MLRPVETQSREIKKLDGLWSFCTDADDCGIAQQWWRQPLPQSRAIAVPGSYNDQFADAEIRNYVGNVWYQLNVRIPKGWE
HQRIVLRFDAVTHYGKVWVNDHAVMEHQGGYTPFEADISHLAAAGESIRITVCVNNELSWQTIPPGVVTRDETGKRQQSY
FHDFFNYAGIHRSVMLYTTPKTFVQDITVTTEVANDLSRATLSWRVEANGEVRVELRDAGQHIVAYGEGAKGELQIAAPR
LWQPGEGYLYELRVIAQHQDERDDYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMSW
IGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLSLGIGFDSCEKPKALYSEEGVNDETQRAHLKAIQELIARDK
NHPSVVMWSIANEPDTRPEGARDYFAPLAQATRELDPTRPITCVNVMFCDVETDTITDLFDVVCLNRYYGWYVQSGDLAK
AEKVLEKELLAWQEKLHRPIIMTEYGVDTLAGLHSMYSDMWSEEYQCAWLEMYHRVFDRVSAVVGEQVWNFADFATSQGI
MRVGGNRKGIFTRDRRPKSAAFILQKRWTGMTFGEKPQQGEKS

Sequences:

>Translated_603_residues
MLRPVETQSREIKKLDGLWSFCTDADDCGIAQQWWRQPLPQSRAIAVPGSYNDQFADAEIRNYVGNVWYQLNVRIPKGWE
HQRIVLRFDAVTHYGKVWVNDHAVMEHQGGYTPFEADISHLAAAGESIRITVCVNNELSWQTIPPGVVTRDETGKRQQSY
FHDFFNYAGIHRSVMLYTTPKTFVQDITVTTEVANDLSRATLSWRVEANGEVRVELRDAGQHIVAYGEGAKGELQIAAPR
LWQPGEGYLYELRVIAQHQDERDDYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMSW
IGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLSLGIGFDSCEKPKALYSEEGVNDETQRAHLKAIQELIARDK
NHPSVVMWSIANEPDTRPEGARDYFAPLAQATRELDPTRPITCVNVMFCDVETDTITDLFDVVCLNRYYGWYVQSGDLAK
AEKVLEKELLAWQEKLHRPIIMTEYGVDTLAGLHSMYSDMWSEEYQCAWLEMYHRVFDRVSAVVGEQVWNFADFATSQGI
MRVGGNRKGIFTRDRRPKSAAFILQKRWTGMTFGEKPQQGEKS
>Mature_603_residues
MLRPVETQSREIKKLDGLWSFCTDADDCGIAQQWWRQPLPQSRAIAVPGSYNDQFADAEIRNYVGNVWYQLNVRIPKGWE
HQRIVLRFDAVTHYGKVWVNDHAVMEHQGGYTPFEADISHLAAAGESIRITVCVNNELSWQTIPPGVVTRDETGKRQQSY
FHDFFNYAGIHRSVMLYTTPKTFVQDITVTTEVANDLSRATLSWRVEANGEVRVELRDAGQHIVAYGEGAKGELQIAAPR
LWQPGEGYLYELRVIAQHQDERDDYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMSW
IGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLSLGIGFDSCEKPKALYSEEGVNDETQRAHLKAIQELIARDK
NHPSVVMWSIANEPDTRPEGARDYFAPLAQATRELDPTRPITCVNVMFCDVETDTITDLFDVVCLNRYYGWYVQSGDLAK
AEKVLEKELLAWQEKLHRPIIMTEYGVDTLAGLHSMYSDMWSEEYQCAWLEMYHRVFDRVSAVVGEQVWNFADFATSQGI
MRVGGNRKGIFTRDRRPKSAAFILQKRWTGMTFGEKPQQGEKS

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=619, Percent_Identity=44.7495961227787, Blast_Score=496, Evalue=1e-140,
Organism=Escherichia coli, GI1787903, Length=602, Percent_Identity=82.2259136212625, Blast_Score=1054, Evalue=0.0,
Organism=Escherichia coli, GI1786539, Length=495, Percent_Identity=25.8585858585859, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI48994920, Length=424, Percent_Identity=25.4716981132075, Blast_Score=99, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17510825, Length=618, Percent_Identity=37.378640776699, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI62471735, Length=624, Percent_Identity=41.9871794871795, Blast_Score=479, Evalue=1e-135,
Organism=Drosophila melanogaster, GI19922582, Length=624, Percent_Identity=41.9871794871795, Blast_Score=479, Evalue=1e-135,
Organism=Drosophila melanogaster, GI24655438, Length=624, Percent_Identity=41.9871794871795, Blast_Score=479, Evalue=1e-135,
Organism=Drosophila melanogaster, GI24651745, Length=629, Percent_Identity=39.4276629570747, Blast_Score=434, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.31 [H]

Molecular weight: Translated: 68897; Mature: 68897

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00719 GLYCOSYL_HYDROL_F2_1 ; PS00608 GLYCOSYL_HYDROL_F2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPVETQSREIKKLDGLWSFCTDADDCGIAQQWWRQPLPQSRAIAVPGSYNDQFADAEI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCHHHH
RNYVGNVWYQLNVRIPKGWEHQRIVLRFDAVTHYGKVWVNDHAVMEHQGGYTPFEADISH
HHHHCCEEEEEEEECCCCCCCCEEEEEEECHHCCCEEEECCCEEEECCCCCCCHHHHHHH
LAAAGESIRITVCVNNELSWQTIPPGVVTRDETGKRQQSYFHDFFNYAGIHRSVMLYTTP
HHHCCCEEEEEEEECCCCCCEECCCCCEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECC
KTFVQDITVTTEVANDLSRATLSWRVEANGEVRVELRDAGQHIVAYGEGAKGELQIAAPR
HHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEEEEECCCCEEEEECCCCCCEEEEECCC
LWQPGEGYLYELRVIAQHQDERDDYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDAD
CCCCCCCCEEEEEEEECCCCCCCCCCEEECHHHHEECCCEEEEECCCEEEECCCCCCCCC
LRGKGFDNVLMVHDHALMSWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLS
CCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCEEEEEEE
LGIGFDSCEKPKALYSEEGVNDETQRAHLKAIQELIARDKNHPSVVMWSIANEPDTRPEG
EECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
ARDYFAPLAQATRELDPTRPITCVNVMFCDVETDTITDLFDVVCLNRYYGWYVQSGDLAK
CHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCEEEECCCHHH
AEKVLEKELLAWQEKLHRPIIMTEYGVDTLAGLHSMYSDMWSEEYQCAWLEMYHRVFDRV
HHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SAVVGEQVWNFADFATSQGIMRVGGNRKGIFTRDRRPKSAAFILQKRWTGMTFGEKPQQG
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCCC
EKS
CCC
>Mature Secondary Structure
MLRPVETQSREIKKLDGLWSFCTDADDCGIAQQWWRQPLPQSRAIAVPGSYNDQFADAEI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCHHHH
RNYVGNVWYQLNVRIPKGWEHQRIVLRFDAVTHYGKVWVNDHAVMEHQGGYTPFEADISH
HHHHCCEEEEEEEECCCCCCCCEEEEEEECHHCCCEEEECCCEEEECCCCCCCHHHHHHH
LAAAGESIRITVCVNNELSWQTIPPGVVTRDETGKRQQSYFHDFFNYAGIHRSVMLYTTP
HHHCCCEEEEEEEECCCCCCEECCCCCEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECC
KTFVQDITVTTEVANDLSRATLSWRVEANGEVRVELRDAGQHIVAYGEGAKGELQIAAPR
HHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEEEEECCCCEEEEECCCCCCEEEEECCC
LWQPGEGYLYELRVIAQHQDERDDYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDAD
CCCCCCCCEEEEEEEECCCCCCCCCCEEECHHHHEECCCEEEEECCCEEEECCCCCCCCC
LRGKGFDNVLMVHDHALMSWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLS
CCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCEEEEEEE
LGIGFDSCEKPKALYSEEGVNDETQRAHLKAIQELIARDKNHPSVVMWSIANEPDTRPEG
EECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
ARDYFAPLAQATRELDPTRPITCVNVMFCDVETDTITDLFDVVCLNRYYGWYVQSGDLAK
CHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCEEEECCCHHH
AEKVLEKELLAWQEKLHRPIIMTEYGVDTLAGLHSMYSDMWSEEYQCAWLEMYHRVFDRV
HHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SAVVGEQVWNFADFATSQGIMRVGGNRKGIFTRDRRPKSAAFILQKRWTGMTFGEKPQQG
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCCC
EKS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534890; 8125312; 2103475; 9097039; 9278503 [H]