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The map label for this gene is katE [H]

Identifier: 194735428

GI number: 194735428

Start: 1363786

End: 1366038

Strand: Reverse

Name: katE [H]

Synonym: SeSA_A1415

Alternate gene names: 194735428

Gene position: 1366038-1363786 (Counterclockwise)

Preceding gene: 194736967

Following gene: 194734313

Centisome position: 29.01

GC content: 54.15

Gene sequence:

>2253_bases
ATGTCGCATAATGAGAAATCCCCCCATCAGTCCCCCGTGCATGATACCCGTGAATCACAGCCCGGCCTGGACTCCCTGGC
ACCGTCAGACGGTTCACATCGCCCCACGCCAGAACCGACGCCGCCGGGCGCGCAACCAACGGCCCCCGGCAGCTTAAAAG
CGCCCGAGACCGCGAATGATAAGCTCACCGCCCTCGACGCCTTTCGTAAAGGCAGCGAAAATTATGCGCTGACCACCAAT
CAGGGCGTGCGCATCGCCGACGATCAAAATTCTCTTCGCGCCGGCAGCCGTGGCCCTACGCTGTTGGAAGATTTTATCCT
GCGCGAGAAAATTACCCACTTTGACCATGAGCGTATCCCGGAGAGGATCGTTCACGCCCGCGGATCTGCAGCGCACGGCT
ATTTCCAGCCATATAAAGACCTGAGCGACATCACGAAAGCCGCGTTTCTGTGCGATCCACAGAAAATTACCCCGGTCTTT
GTTCGCTTTTCGACAGTACAGGGCGGCGCGGGGTCTGCTGATACCGTACGTGATATCCGCGGTTTTGCGACCAAATTTTA
TACCGAAGAGGGAATTTTCGATCTCGTCGGTAATAACACGCCGATCTTTTTTATCCAGGATGCGCATAAGTTTCCGGATT
TTGTGCACGCCGTTAAGCCCGAACCACATTGGGCTATTCCGCAAGGACAGAGCGCGCACGACACCTTCTGGGACTATGTT
TCCTTACAGCCTGAGACGCTGCACAACGTCATGTGGGCAATGTCGGATCGCGGTATTCCACGGAGTTATCGGACGATGGA
AGGGTTCGGCATTCACACCTTCCGTCTGATCAATGCACAAGGGAAAGCGACCTTTGTCCGTTTCCACTGGAAACCGTTGG
CAGGTAAAGCCTCGCTGGTGTGGGATGAGTCACAAAAACTGACCGGTCGCGATCCGGATTTTCACCGCAGGGATCTGTGG
GAGGCCATCGAAGCGGGCGATTTCCCGGAATACGAGCTGGGCCTACAACTCATTGCCGAAGAGGATGAATTTAAATTCGA
TTTTGATCTGCTCGATCCGACCAAACTGATTCCGGAAGAGCTGGTGCCAGTACAACGCGTCGGCAAAATGGTGTTAAACC
GTAATCCGGATAACTTTTTCGCTGAAAACGAACAGGCGGCATTTCATCCAGGGCATATTGTTCCCGGCATTGATTTTACC
AACGATCCGCTGTTACAGGGGCGTCTGTTCTCTTATACCGACACGCAAATCAGTCGTCTGGGCGGGCCAAACTTCCACGA
AATTCCGATTAACCGCCCTACCTGCCCCTACCATAACTTCCAGCGTGACGGTATGCACCGGATGGATATCGACACCAATC
CGGCGAACTATGAACCAAACTCCATTAATGACAACTGGCCGCGCGAAACGCCGCCAGCGCCAAAACGCGGCGGCTTCGAA
TCATACCAGGAACGCGTGGATGGCAATAAAATCCGCGAACGCAGCCCCTCTTTCGGTGAATATTACTCGCATCCTCGCCT
GTTCTGGCTCAGTCAGACGCCGATAGAACAGCAGCATATTATTGACGCGTTCAGCTTTGAACTGGGTAAAGTCGCCCGCG
CGTATATTCGGGAGCGGGTGGTCGATCAGTTAGCGCATATTGATGTCACGCTGGCTGAGGGCGTCGCGCATAATCTCGGT
TTTGCACTCACCCATGAGCAAACGCAAATTGCCCCGCCTCCTGATGTCAACGGTCTGAAAAAAGATCCGGCGCTCAGCCT
GTATGCGGTGCCGGACGGCGATGTTAAAGGCCGCGTGGTCGCTATCCTGCTGAACGACAAGGTTAACGCCGCCGATCTGC
TGACCATTTTGCAGGCTTTAAAAGCTAAAGGCGTCCACGCAAAACTGCTCTATTCACGGATGGGTGAAGTAACGGCTGAT
GACGGTTCAACATTAACTATTGCGGCAACCTTTGCCGGCGCGCCGTCGCTAACGGTCGATGCGGTAATAGTACCGTGCGG
CAATATTGCCGATATCGAGAGTTGCGGCGATGCTCGTTACTACCTTCTGGAAGCCTACAAACATCTGAAGCCCATCGCAC
TGGCAGGCGACGCCCGACGGTTTAAGGCGCTTTTAAACATTGATAGCCAGGGGGAAGAAGGACTTGTTGAGGCAGATAAC
GTTGACCACCACTTTATGGACACTCTGCTGACGTTGATGGCGGCACACCGTGTCTGGTCGCGTGCGGGGAAAATTAACGC
GATTCCTGCATAA

Upstream 100 bases:

>100_bases
TTCCGCTCTCCCCCGGCATAATTGCTGAAATGTTCTATAGTTAGAGTGATTTTGACTACTACCACGCCCATTTCAGTGAT
GAAAGCAGGAGACGAGTTCA

Downstream 100 bases:

>100_bases
ACGGCAAAAAATGCGGCGCATTCTTGCGCCGCAAACTCAGGAGCTAAATATCAAGAAAACTGCCAGGACGATATCCACGT
TCCGCAATCGCTGCCTTGAG

Product: hydroperoxidase II

Products: NA

Alternate protein names: Hydroxyperoxidase II [H]

Number of amino acids: Translated: 750; Mature: 749

Protein sequence:

>750_residues
MSHNEKSPHQSPVHDTRESQPGLDSLAPSDGSHRPTPEPTPPGAQPTAPGSLKAPETANDKLTALDAFRKGSENYALTTN
QGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKDLSDITKAAFLCDPQKITPVF
VRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYV
SLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAQGKATFVRFHWKPLAGKASLVWDESQKLTGRDPDFHRRDLW
EAIEAGDFPEYELGLQLIAEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGIDFT
NDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMDIDTNPANYEPNSINDNWPRETPPAPKRGGFE
SYQERVDGNKIRERSPSFGEYYSHPRLFWLSQTPIEQQHIIDAFSFELGKVARAYIRERVVDQLAHIDVTLAEGVAHNLG
FALTHEQTQIAPPPDVNGLKKDPALSLYAVPDGDVKGRVVAILLNDKVNAADLLTILQALKAKGVHAKLLYSRMGEVTAD
DGSTLTIAATFAGAPSLTVDAVIVPCGNIADIESCGDARYYLLEAYKHLKPIALAGDARRFKALLNIDSQGEEGLVEADN
VDHHFMDTLLTLMAAHRVWSRAGKINAIPA

Sequences:

>Translated_750_residues
MSHNEKSPHQSPVHDTRESQPGLDSLAPSDGSHRPTPEPTPPGAQPTAPGSLKAPETANDKLTALDAFRKGSENYALTTN
QGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKDLSDITKAAFLCDPQKITPVF
VRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYV
SLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAQGKATFVRFHWKPLAGKASLVWDESQKLTGRDPDFHRRDLW
EAIEAGDFPEYELGLQLIAEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGIDFT
NDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMDIDTNPANYEPNSINDNWPRETPPAPKRGGFE
SYQERVDGNKIRERSPSFGEYYSHPRLFWLSQTPIEQQHIIDAFSFELGKVARAYIRERVVDQLAHIDVTLAEGVAHNLG
FALTHEQTQIAPPPDVNGLKKDPALSLYAVPDGDVKGRVVAILLNDKVNAADLLTILQALKAKGVHAKLLYSRMGEVTAD
DGSTLTIAATFAGAPSLTVDAVIVPCGNIADIESCGDARYYLLEAYKHLKPIALAGDARRFKALLNIDSQGEEGLVEADN
VDHHFMDTLLTLMAAHRVWSRAGKINAIPA
>Mature_749_residues
SHNEKSPHQSPVHDTRESQPGLDSLAPSDGSHRPTPEPTPPGAQPTAPGSLKAPETANDKLTALDAFRKGSENYALTTNQ
GVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKDLSDITKAAFLCDPQKITPVFV
RFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVS
LQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAQGKATFVRFHWKPLAGKASLVWDESQKLTGRDPDFHRRDLWE
AIEAGDFPEYELGLQLIAEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGIDFTN
DPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMDIDTNPANYEPNSINDNWPRETPPAPKRGGFES
YQERVDGNKIRERSPSFGEYYSHPRLFWLSQTPIEQQHIIDAFSFELGKVARAYIRERVVDQLAHIDVTLAEGVAHNLGF
ALTHEQTQIAPPPDVNGLKKDPALSLYAVPDGDVKGRVVAILLNDKVNAADLLTILQALKAKGVHAKLLYSRMGEVTADD
GSTLTIAATFAGAPSLTVDAVIVPCGNIADIESCGDARYYLLEAYKHLKPIALAGDARRFKALLNIDSQGEEGLVEADNV
DHHFMDTLLTLMAAHRVWSRAGKINAIPA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=423, Percent_Identity=45.6264775413712, Blast_Score=355, Evalue=8e-98,
Organism=Escherichia coli, GI48994891, Length=750, Percent_Identity=88.9333333333333, Blast_Score=1392, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71998444, Length=443, Percent_Identity=46.5011286681716, Blast_Score=384, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI25151141, Length=506, Percent_Identity=42.0948616600791, Blast_Score=377, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI25147792, Length=494, Percent_Identity=42.1052631578947, Blast_Score=374, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6320462, Length=501, Percent_Identity=39.3213572854291, Blast_Score=317, Evalue=6e-87,
Organism=Saccharomyces cerevisiae, GI6321525, Length=367, Percent_Identity=41.6893732970027, Blast_Score=287, Evalue=4e-78,
Organism=Drosophila melanogaster, GI17981717, Length=495, Percent_Identity=41.010101010101, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI19920968, Length=404, Percent_Identity=44.3069306930693, Blast_Score=341, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 83610; Mature: 83478

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNEKSPHQSPVHDTRESQPGLDSLAPSDGSHRPTPEPTPPGAQPTAPGSLKAPETAND
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KLTALDAFRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIP
CHHHHHHHHCCCCCEEEECCCCEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHCCHHHHH
ERIVHARGSAAHGYFQPYKDLSDITKAAFLCDPQKITPVFVRFSTVQGGAGSADTVRDIR
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHH
GFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYV
HHHHHHHCCCCCCEECCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHH
SLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAQGKATFVRFHWKPLAGKASLV
CCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCCEEEEEEEEEECCCCEEEE
WDESQKLTGRDPDFHRRDLWEAIEAGDFPEYELGLQLIAEEDEFKFDFDLLDPTKLIPEE
ECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCEEEEECCCCCEEEEECCCCHHHCHHH
LVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGIDFTNDPLLQGRLFSYTDTQISRL
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHC
GGPNFHEIPINRPTCPYHNFQRDGMHRMDIDTNPANYEPNSINDNWPRETPPAPKRGGFE
CCCCCEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
SYQERVDGNKIRERSPSFGEYYSHPRLFWLSQTPIEQQHIIDAFSFELGKVARAYIRERV
HHHHHCCCCHHHHCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VDQLAHIDVTLAEGVAHNLGFALTHEQTQIAPPPDVNGLKKDPALSLYAVPDGDVKGRVV
HHHHHHCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEE
AILLNDKVNAADLLTILQALKAKGVHAKLLYSRMGEVTADDGSTLTIAATFAGAPSLTVD
EEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCEECCCCCEEEEEEEECCCCCCEEE
AVIVPCGNIADIESCGDARYYLLEAYKHLKPIALAGDARRFKALLNIDSQGEEGLVEADN
EEEECCCCCCCHHHCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHCCCCCCCCCCEECCC
VDHHFMDTLLTLMAAHRVWSRAGKINAIPA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SHNEKSPHQSPVHDTRESQPGLDSLAPSDGSHRPTPEPTPPGAQPTAPGSLKAPETAND
CCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KLTALDAFRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIP
CHHHHHHHHCCCCCEEEECCCCEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHCCHHHHH
ERIVHARGSAAHGYFQPYKDLSDITKAAFLCDPQKITPVFVRFSTVQGGAGSADTVRDIR
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHH
GFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYV
HHHHHHHCCCCCCEECCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHH
SLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAQGKATFVRFHWKPLAGKASLV
CCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCCEEEEEEEEEECCCCEEEE
WDESQKLTGRDPDFHRRDLWEAIEAGDFPEYELGLQLIAEEDEFKFDFDLLDPTKLIPEE
ECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCEEEEECCCCCEEEEECCCCHHHCHHH
LVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGIDFTNDPLLQGRLFSYTDTQISRL
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHC
GGPNFHEIPINRPTCPYHNFQRDGMHRMDIDTNPANYEPNSINDNWPRETPPAPKRGGFE
CCCCCEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
SYQERVDGNKIRERSPSFGEYYSHPRLFWLSQTPIEQQHIIDAFSFELGKVARAYIRERV
HHHHHCCCCHHHHCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VDQLAHIDVTLAEGVAHNLGFALTHEQTQIAPPPDVNGLKKDPALSLYAVPDGDVKGRVV
HHHHHHCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEE
AILLNDKVNAADLLTILQALKAKGVHAKLLYSRMGEVTADDGSTLTIAATFAGAPSLTVD
EEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCEECCCCCEEEEEEEECCCCCCEEE
AVIVPCGNIADIESCGDARYYLLEAYKHLKPIALAGDARRFKALLNIDSQGEEGLVEADN
EEEECCCCCCCHHHCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHCCCCCCCCCCEECCC
VDHHFMDTLLTLMAAHRVWSRAGKINAIPA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987146; 9097039; 9278503; 9144772; 7663946; 10091651; 11455600 [H]