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The map label for this gene is rpe [H]

Identifier: 194735372

GI number: 194735372

Start: 3535002

End: 3535679

Strand: Reverse

Name: rpe [H]

Synonym: SeSA_A3680

Alternate gene names: 194735372

Gene position: 3535679-3535002 (Counterclockwise)

Preceding gene: 194734864

Following gene: 194735884

Centisome position: 75.08

GC content: 54.13

Gene sequence:

>678_bases
ATGAAACAGTATTTGATTGCCCCCTCAATTCTGTCGGCTGATTTTGCTCGCCTGGGTGAAGACACCGCCAAAGCGCTGGC
TGCCGGTGCTGATGTTGTACACTTTGACGTCATGGATAATCACTATGTGCCGAACCTGACTATCGGCCCGATGGTGCTGA
AATCCCTGCGTCAGTACGGTATTACCGCGCCTATTGATGTCCACCTGATGGTCAAGCCAGTCGACCGTATCGTGCCCGAC
TTTGCCGCCGCTGGCGCGAGCATCATTACCTTTCACCCGGAAGCCTCCGAACATGTTGACCGCACGCTACAGCTGATTAA
AGAGCACGGCTGTAAAGCGGGGCTGGTATTCAACCCGGCAACGCCGCTCAGTTATCTCGATTACGTCATGGACAAACTGG
ATGTGATCCTGCTGATGTCCGTGAACCCAGGCTTCGGCGGCCAGTCTTTTATTCCGCAGACGCTGGATAAACTGCGCGAA
GTGCGACGCCGCATTGATGCGTCCGGTTACGACATTCGCCTGGAAGTGGATGGCGGCGTGAAGGTGAACAATATCGGCGA
GATCGCCGCAGCAGGCGCGGACATGTTTGTTGCGGGGTCGGCAATTTTCGATAAGCCCGACTACAAAAAAGTGATTGATG
AAATGCGCAGTGAGCTGGCAAAGGTAAGTCATGGATAA

Upstream 100 bases:

>100_bases
GCAGCAACGGCGGCACACGTAAAAAGGTGGACGAACTGCTGGCTCTGTACCAACCAGGAGTCGCCACGCCTGCAAGAAAA
TAATTCTCAAGGAGAAGCGG

Downstream 100 bases:

>100_bases
GTTGCAGAATATTCGGGGCGTCGCCTTTGATCTTGACGGCACGCTGGTGGATAGCGCGCCGGGTCTTGCCGCGGCGGTGG
ATATGGCGCTGTATGCGCTG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDASGYDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHG

Sequences:

>Translated_225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDASGYDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHG
>Mature_225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDASGYDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHG

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=220, Percent_Identity=40, Blast_Score=163, Evalue=1e-40,
Organism=Homo sapiens, GI219879828, Length=213, Percent_Identity=39.906103286385, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI24307923, Length=176, Percent_Identity=32.3863636363636, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1789788, Length=224, Percent_Identity=97.7678571428571, Blast_Score=446, Evalue=1e-127,
Organism=Escherichia coli, GI1790523, Length=197, Percent_Identity=38.0710659898477, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790754, Length=212, Percent_Identity=29.2452830188679, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=217, Percent_Identity=40.5529953917051, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6322341, Length=233, Percent_Identity=38.6266094420601, Blast_Score=158, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24586301, Length=214, Percent_Identity=40.1869158878505, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24478; Mature: 24478

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYG
CCCEECCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCC
ITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRRRIDASGYDIRLEVDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHG
EECCCCHHHHCCCCCEEECCHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYG
CCCEECCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCC
ITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRRRIDASGYDIRLEVDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHG
EECCCCHHHHCCCCCEEECCHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]