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The map label for this gene is aroL [H]

Identifier: 194735163

GI number: 194735163

Start: 453693

End: 454238

Strand: Direct

Name: aroL [H]

Synonym: SeSA_A0444

Alternate gene names: 194735163

Gene position: 453693-454238 (Clockwise)

Preceding gene: 194736550

Following gene: 194738188

Centisome position: 9.63

GC content: 57.88

Gene sequence:

>546_bases
ATGATGCAACCTCTTTATCTTGTTGGCCCGCGGGGCTGTGGGAAAACCACCATCGGTATGGCGCTGGCGCAGGCAACCGG
TTTTCGGTTTGCAGATACCGACCGCTGGCTGCAATCGCACGTGCAGATGAGCGTCGCTGATATCGTTGAAAAAGAAGGCT
GGGGAGGGTTCCGCGCCCGGGAAACCGCGGCCCTGGAAGCGGTAAGCGCGCCTTCGACTGTTGTGGCGACGGGGGGCGGT
ATTATTCTCACGGAGTATAACCGACGTTATATGCACCGTGTTGGCGTAGTGATTTATCTGTGCGCGCCGGTATCCACGCT
GGTTAACCGGCTTGAGGCTGAACCTGAAGCGGAGCTGCGCCCGACCCTCACCGGCAAGCCGTTGAGCGAAGAGGTTCGGG
AAGTGCTTGAGCAGCGTGACGCGTTGTATCGCGAAACGGCGCATTACATTATTGACGCGACGAAAACGCCGGCCCAGGTC
GTTTCTGAAATTATTGCGGCGTTGCCGCCGTCGACGCAACGGTTACAGGGAGATGTCTATACTTAA

Upstream 100 bases:

>100_bases
TTATTGTTTACATTTATGCGTTGTACTAGTTAGATGATATGATTATAACATTGCTGATATCAAATCCTGCGTATGCGCAG
TTCCTGGGGGAACGCCTGCT

Downstream 100 bases:

>100_bases
CGCTCACCCAGAATAAAGGAAACGCTATGCCAACCAGACCACCTTATCCGCGGGAAGCTTATATCGTCACCATTGAAAAA
GGCACGCCGGGCCAGACGGT

Product: shikimate kinase II

Products: NA

Alternate protein names: SK 2 [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRARETAALEAVSAPSTVVATGGG
IILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEAELRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKTPAQV
VSEIIAALPPSTQRLQGDVYT

Sequences:

>Translated_181_residues
MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRARETAALEAVSAPSTVVATGGG
IILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEAELRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKTPAQV
VSEIIAALPPSTQRLQGDVYT
>Mature_181_residues
MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRARETAALEAVSAPSTVVATGGG
IILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEAELRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKTPAQV
VSEIIAALPPSTQRLQGDVYT

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family. AroL subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786587, Length=168, Percent_Identity=73.8095238095238, Blast_Score=268, Evalue=1e-73,
Organism=Escherichia coli, GI87082255, Length=170, Percent_Identity=32.9411764705882, Blast_Score=81, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320332, Length=166, Percent_Identity=28.9156626506024, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19848; Mature: 19848

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRAR
CCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEAELR
HHHHHHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKTPAQVVSEIIAALPPSTQRLQGDVY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCHHHCCCCCC
T
C
>Mature Secondary Structure
MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRAR
CCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEAELR
HHHHHHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKTPAQVVSEIIAALPPSTQRLQGDVY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCHHHCCCCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA