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The map label for this gene is hofC [H]

Identifier: 194735161

GI number: 194735161

Start: 165014

End: 166216

Strand: Reverse

Name: hofC [H]

Synonym: SeSA_A0159

Alternate gene names: 194735161

Gene position: 166216-165014 (Counterclockwise)

Preceding gene: 194734628

Following gene: 194734613

Centisome position: 3.53

GC content: 55.03

Gene sequence:

>1203_bases
ATGAGCGTTAAACAGCTCTGGCGCTGGCAAGGCGTTAACGATAAAGGTCAACTGGAACAAGGCGTTGTATGGGTGGACAA
TCGTCTGGCGCTGATCATCACCCTGCAACATCAGCGCATTATGCCGCTTCGCATCAAGCGCATGGGCGTTAACGCCGCAC
TGTGGAAAGAAGAGCAAAGCGCTGAAATTATTCATCAGTTGGCCACGCTCATTCATGCCGGACTGACGCTTTCTGAAGGG
CTGGAACTCCTTGCGCAACAGCATCCCCACCGACAATGGCAAGCGCTGTTGCGCACGCTGGCTCACGAGCTTGAACAGGG
CGTCCCTTTTTCCAGCGCATTAGTCTCCTGGCCGCAGGTATTTCCGCCGCTCTACCAGACGATGATCCGCACCGGAGAAC
TGACCGGCAAACTGGCCGAATGCTGCTTTGAACTGGCCCGTCAGCAAAAAGCGCAGCGGCAGATTACGGTTAGCGTGAAA
AAGGCGCTGCGCTATCCCGCCATTATTCTGACAATGGCCGCTCTGGTCGTTTTCGCCATGCTGCACTTTGTTCTGCCGGA
ATTTGCCGCCATTTACCGTAGCTTTAATACCCCGCTCCCTCTTCTGACGCGCGGTATTATCGCGATAGCGCAATGGGGGT
CGGCATGGGGTTGGCTCATCTTGTTCCTGGCGATGCTCGTTGCTATCGCTCACCGCAGGGTAAAACAAAAGCCGTCCTGG
CAAGCGCAGCGGCAGCGTCTTCTGCTACGGCTTCCCGTTATGGGTCGCCTGATAAGAGGCCAGAAACTAGCGCAAATATT
CACCGTACTGGCATTGACCCAAAGCGCAGGCATTCCTTTTCTTCAGGGACTGGAAAGCGCTATCGATAGCCTCGGCTGCC
CTTACTGGTCACAGCGTTTAACGCAGGTACATCAGGAGATCGCCGCGGGCAATCCGGTCTGGTTGGCGCTAAAAAATACC
CAGGAATTTAGTCCGCTATGCCTGCAACTGGTCAGAACGGGCGAAGCGTCCGGTTCACTCGATATCATGCTGCATAACCT
TGCCCGTCACCACAGTGAAACTACGCTGGCGCTGGCCGATAATCTGGCGTCGCTGTTGGAACCGGCGTTATTGATCATCA
CCGGCTTAATTATCGGTACGCTGGTGGTGGCGATGTATTTGCCGATTTTTCATCTGGGAGACGCGATGAGCGGGATGGGA
TAA

Upstream 100 bases:

>100_bases
CAACAGACCGGTACAGGGACGCTTTTTGAAAATGGCTGTCGCGCCGTTGAGCAAGGCATGACGTCCTTTGAAGAGATACT
GCGCGTTCTGGGAATGCCCC

Downstream 100 bases:

>100_bases
GGCTGGCGCACATTTACGCCAGCCAGAATATTAGAGGCTATTGAAAATGCGGTTTTCTTGTTCCTGCACCCGAATAAAGG
TGGTGCGTTTGGTCAACTCT

Product: type IV pilin biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSVKQLWRWQGVNDKGQLEQGVVWVDNRLALIITLQHQRIMPLRIKRMGVNAALWKEEQSAEIIHQLATLIHAGLTLSEG
LELLAQQHPHRQWQALLRTLAHELEQGVPFSSALVSWPQVFPPLYQTMIRTGELTGKLAECCFELARQQKAQRQITVSVK
KALRYPAIILTMAALVVFAMLHFVLPEFAAIYRSFNTPLPLLTRGIIAIAQWGSAWGWLILFLAMLVAIAHRRVKQKPSW
QAQRQRLLLRLPVMGRLIRGQKLAQIFTVLALTQSAGIPFLQGLESAIDSLGCPYWSQRLTQVHQEIAAGNPVWLALKNT
QEFSPLCLQLVRTGEASGSLDIMLHNLARHHSETTLALADNLASLLEPALLIITGLIIGTLVVAMYLPIFHLGDAMSGMG

Sequences:

>Translated_400_residues
MSVKQLWRWQGVNDKGQLEQGVVWVDNRLALIITLQHQRIMPLRIKRMGVNAALWKEEQSAEIIHQLATLIHAGLTLSEG
LELLAQQHPHRQWQALLRTLAHELEQGVPFSSALVSWPQVFPPLYQTMIRTGELTGKLAECCFELARQQKAQRQITVSVK
KALRYPAIILTMAALVVFAMLHFVLPEFAAIYRSFNTPLPLLTRGIIAIAQWGSAWGWLILFLAMLVAIAHRRVKQKPSW
QAQRQRLLLRLPVMGRLIRGQKLAQIFTVLALTQSAGIPFLQGLESAIDSLGCPYWSQRLTQVHQEIAAGNPVWLALKNT
QEFSPLCLQLVRTGEASGSLDIMLHNLARHHSETTLALADNLASLLEPALLIITGLIIGTLVVAMYLPIFHLGDAMSGMG
>Mature_399_residues
SVKQLWRWQGVNDKGQLEQGVVWVDNRLALIITLQHQRIMPLRIKRMGVNAALWKEEQSAEIIHQLATLIHAGLTLSEGL
ELLAQQHPHRQWQALLRTLAHELEQGVPFSSALVSWPQVFPPLYQTMIRTGELTGKLAECCFELARQQKAQRQITVSVKK
ALRYPAIILTMAALVVFAMLHFVLPEFAAIYRSFNTPLPLLTRGIIAIAQWGSAWGWLILFLAMLVAIAHRRVKQKPSWQ
AQRQRLLLRLPVMGRLIRGQKLAQIFTVLALTQSAGIPFLQGLESAIDSLGCPYWSQRLTQVHQEIAAGNPVWLALKNTQ
EFSPLCLQLVRTGEASGSLDIMLHNLARHHSETTLALADNLASLLEPALLIITGLIIGTLVVAMYLPIFHLGDAMSGMG

Specific function: Unknown

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1786295, Length=400, Percent_Identity=67.75, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1789724, Length=403, Percent_Identity=27.7915632754342, Blast_Score=148, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44732; Mature: 44600

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKQLWRWQGVNDKGQLEQGVVWVDNRLALIITLQHQRIMPLRIKRMGVNAALWKEEQS
CCHHHHHHHCCCCCCCCHHCCEEEECCCEEEEEEECCCCCCHHHHHHHCCCHHHHCCHHH
AEIIHQLATLIHAGLTLSEGLELLAQQHPHRQWQALLRTLAHELEQGVPFSSALVSWPQV
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHH
FPPLYQTMIRTGELTGKLAECCFELARQQKAQRQITVSVKKALRYPAIILTMAALVVFAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHFVLPEFAAIYRSFNTPLPLLTRGIIAIAQWGSAWGWLILFLAMLVAIAHRRVKQKPSW
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCH
QAQRQRLLLRLPVMGRLIRGQKLAQIFTVLALTQSAGIPFLQGLESAIDSLGCPYWSQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHH
TQVHQEIAAGNPVWLALKNTQEFSPLCLQLVRTGEASGSLDIMLHNLARHHSETTLALAD
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
NLASLLEPALLIITGLIIGTLVVAMYLPIFHLGDAMSGMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVKQLWRWQGVNDKGQLEQGVVWVDNRLALIITLQHQRIMPLRIKRMGVNAALWKEEQS
CHHHHHHHCCCCCCCCHHCCEEEECCCEEEEEEECCCCCCHHHHHHHCCCHHHHCCHHH
AEIIHQLATLIHAGLTLSEGLELLAQQHPHRQWQALLRTLAHELEQGVPFSSALVSWPQV
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHH
FPPLYQTMIRTGELTGKLAECCFELARQQKAQRQITVSVKKALRYPAIILTMAALVVFAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHFVLPEFAAIYRSFNTPLPLLTRGIIAIAQWGSAWGWLILFLAMLVAIAHRRVKQKPSW
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCH
QAQRQRLLLRLPVMGRLIRGQKLAQIFTVLALTQSAGIPFLQGLESAIDSLGCPYWSQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHH
TQVHQEIAAGNPVWLALKNTQEFSPLCLQLVRTGEASGSLDIMLHNLARHHSETTLALAD
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
NLASLLEPALLIITGLIIGTLVVAMYLPIFHLGDAMSGMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7959070; 8202364; 9278503; 2904262 [H]