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The map label for this gene is yfdZ [H]

Identifier: 194735137

GI number: 194735137

Start: 2518685

End: 2519923

Strand: Reverse

Name: yfdZ [H]

Synonym: SeSA_A2634

Alternate gene names: 194735137

Gene position: 2519923-2518685 (Counterclockwise)

Preceding gene: 194735671

Following gene: 194738128

Centisome position: 53.51

GC content: 54.16

Gene sequence:

>1239_bases
ATGGCTGACTTCCGCCCTGAACGTCGCTTTACGCGTATCGATCGCCTTCCGCCCTATGTTTTTAACATCACCGCTGAACT
CAAAATGGCTGCGCGTCGGCGCGGCGAAGATATTATTGATTTCAGTATGGGTAATCCTGATGGCGCAACCCCTCCCCACA
TTGTCGAAAAACTTTGCACCGTCGCGCAGCGTCCGGATACGCACGGTTATTCCACGTCTCGCGGCATACCGCGCTTACGC
CGCGCGATTTCTCACTGGTATCAGGAACGTTATGATGTCGATATCGATCCGGAAACCGAAGCGATTGTGACCATCGGTTC
CAAAGAGGGACTGGCGCATTTAATGCTGGCGACGCTGGATCATGGTGATACGGTACTGGTGCCGAACCCCAGTTACCCGA
TTCATATCTATGGCGCCGTTATCGCCGGGGCGCAGGTGCGTTCGGTTCCATTGGTAGAGGGGGTGGATTTCTTCAACGAG
CTGGAGCGCGCTATTCGCGAAAGTTATCCGAAACCGAAAATGATGATTTTGGGTTTTCCGTCTAACCCTACGGCCCAGTG
CGTCGAACTGGAATTTTTTGAAAAAGTGGTCGCTCTGGCTAAACGTTATGATGTGCTGGTAGTGCACGATCTGGCGTATG
CCGATATCGTGTACGACGGCTGGAAAGCGCCATCCATTATGCAGGTGCCTGGCGCGCGCGACGTGGCGGTCGAATTTTTC
ACACTGTCGAAAAGCTATAATATGGCGGGCTGGCGTATTGGGTTTATGGTGGGCAATAAAACCCTGGTCAGCGCGCTGGC
GCGCATTAAAAGTTATCACGATTATGGCACCTTTACCCCACTTCAGGTGGCGGCTATCGCCGCTCTGGAAGGCGATCAGC
AGTGCGTGCGCGATATTGCCGAGCAGTATAAACGTCGTCGCGATGTGCTGGTGAAGGGGTTGCATGAGGCGGGCTGGATG
GTTGAAATGCCGAAAGCCTCAATGTACGTCTGGGCGAAAATCCCGGAGCAATATGCGGCGATGGGGTCGCTTGAGTTTGC
CAAGAAGCTGCTGAATGAGGCGAAGGTTTGCGTTTCTCCAGGGATAGGCTTTGGTGACTATGGCGACACCCATGTACGCT
TTGCATTAATAGAGAATCGCGATCGCATTCGCCAGGCCGTCAGAGGGATTAAAGCGATGTTCCGCGCCGATGGCGTGCTG
CCGTCACATCCAAAACCCGTTGAGGCGAGCACGGAGTAG

Upstream 100 bases:

>100_bases
TCTCGACAGGAAGAAAATTTTCAGGCTATTTTCTAAAGGAGCCACCATCGTGGCAGCGTCGCTCGGACGGTCCGGGCGCT
AACGTTAATCTGAGGATATT

Downstream 100 bases:

>100_bases
AAAAGCAAACAGGAGCCCCATGGCTCCTGTTTTTCTTTGCATTGTACTTTTAAATCATCAGGGCGAAAGTACCGGCCCAA
ACGATGACCATAAATGAAAT

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MADFRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLR
RAISHWYQERYDVDIDPETEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
TLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWM
VEMPKASMYVWAKIPEQYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAVRGIKAMFRADGVL
PSHPKPVEASTE

Sequences:

>Translated_412_residues
MADFRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLR
RAISHWYQERYDVDIDPETEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
TLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWM
VEMPKASMYVWAKIPEQYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAVRGIKAMFRADGVL
PSHPKPVEASTE
>Mature_411_residues
ADFRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRR
AISHWYQERYDVDIDPETEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNEL
ERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFFT
LSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMV
EMPKASMYVWAKIPEQYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAVRGIKAMFRADGVLP
SHPKPVEASTE

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=417, Percent_Identity=24.9400479616307, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI56713254, Length=417, Percent_Identity=24.9400479616307, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI95147551, Length=417, Percent_Identity=22.5419664268585, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI169881279, Length=417, Percent_Identity=22.5419664268585, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI169881281, Length=236, Percent_Identity=21.6101694915254, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1788722, Length=412, Percent_Identity=95.873786407767, Blast_Score=820, Evalue=0.0,
Organism=Escherichia coli, GI1786816, Length=337, Percent_Identity=24.9258160237389, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788627, Length=377, Percent_Identity=26.525198938992, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787710, Length=312, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787909, Length=387, Percent_Identity=24.5478036175711, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788332, Length=255, Percent_Identity=27.0588235294118, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=24.3718592964824, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=365, Percent_Identity=24.3835616438356, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=365, Percent_Identity=24.3835616438356, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=21.1195928753181, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=349, Percent_Identity=23.7822349570201, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573069, Length=340, Percent_Identity=26.4705882352941, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24646114, Length=340, Percent_Identity=26.4705882352941, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI28573067, Length=340, Percent_Identity=26.4705882352941, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI28573065, Length=340, Percent_Identity=26.4705882352941, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI45551451, Length=381, Percent_Identity=25.4593175853018, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641770, Length=380, Percent_Identity=25.5263157894737, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641760, Length=380, Percent_Identity=25.5263157894737, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641768, Length=380, Percent_Identity=25.5263157894737, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641766, Length=380, Percent_Identity=25.5263157894737, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641764, Length=380, Percent_Identity=25.5263157894737, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 46220; Mature: 46089

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCT
CCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQRPDTHGYSTSRGIPRLRRAISHWYQERYDVDIDPETEAIVTIGSKEGLAHLMLATLD
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHEEC
HGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNELERAIRESYPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
SNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
CCCCHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCHHEEEEE
TLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKIPEQYAAMGSLEFAKKLLNEAKVCVSP
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCHHHHHHCCHHHHHHHHHCCCEEECC
GIGFGDYGDTHVRFALIENRDRIRQAVRGIKAMFRADGVLPSHPKPVEASTE
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADFRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCT
CCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQRPDTHGYSTSRGIPRLRRAISHWYQERYDVDIDPETEAIVTIGSKEGLAHLMLATLD
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHEEC
HGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNELERAIRESYPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
SNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
CCCCHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCHHEEEEE
TLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKIPEQYAAMGSLEFAKKLLNEAKVCVSP
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCHHHHHHCCHHHHHHHHHCCCEEECC
GIGFGDYGDTHVRFALIENRDRIRQAVRGIKAMFRADGVLPSHPKPVEASTE
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]