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The map label for this gene is nudC [H]

Identifier: 194735127

GI number: 194735127

Start: 4249333

End: 4250106

Strand: Direct

Name: nudC [H]

Synonym: SeSA_A4377

Alternate gene names: 194735127

Gene position: 4249333-4250106 (Clockwise)

Preceding gene: 194734651

Following gene: 194737614

Centisome position: 90.24

GC content: 55.81

Gene sequence:

>774_bases
ATGGATCGTATAATTGAAAAATTAGAGAGTGGCTGGTGGATCGTCAGCCATGAACAAAAATTATGGTTGCCGTATGGGGA
ATTACCACACGGGCTGGCAGCAAATTTCGATCTTGTGGGGCAGCGCGCACTCCGGATAGGTGAATGGCAAGGCGAGCCCG
TCTGGCTGGTGTTACAGCATCGACGCCATGATATGGGATCGGTTCGCCAGGTTATCGATCAGGATGCCGGGCTGTTCCAA
CTGGCGGGACGTGGCGTACAGTTGGCGGAGTTTTACCGATCGCATAAATTTTGCGGCTATTGCGGGCACCCTATGCACCC
GAGTAAAACCGAATGGGCGATGCTGTGCAGCCATTGCCGCGAGCGTTACTACCCGCAAATCGCCCCTTGCATTATCGTCG
CGATCCGCCGTGAGGATTCGATCCTCCTTGCCCAGCATGTTCGCCACCGCAACGGCGTGCATACGGTACTGGCCGGGTTT
GTTGAAGTCGGCGAAACCTTAGAACAGGCGGTCGCGCGAGAGGTAATGGAGGAGAGCGGCATTAAGGTGAAAAATCTGCG
CTATGTGACTTCCCAGCCGTGGCCTTTCCCGCAGTCGCTGATGACCGCTTTCATGGCGGAGTACGACAGCGGCGATATCG
TCATCGACCCGAAAGAGCTGTTGGAAGCAAATTGGTACCGTTATGACGATCTGCCGCTACTGCCGCCGCCGGGCACCGTC
GCGCGCCGTTTGATCGAAGATACGGTGGCAATGTGTCGGGCTGAATATGATTGA

Upstream 100 bases:

>100_bases
TTTAGCATGATTGTCTCCGCAAGTTAGATAAAGGCTGCTCGCCATGAATGTAAAAATAATGTTAACAACATGCCAGTGAA
GCAAAGGTAGTGCAAGAGCT

Downstream 100 bases:

>100_bases
CATGTTACACTGGGCGCATCAACGCTAAAGGAATGTAAAAATGACCGAACTCAAAAACGATCGTTATCTACGTGCGCTGC
TGCGCCAGCCCGTTGATGTT

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQ
LAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGF
VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTV
ARRLIEDTVAMCRAEYD

Sequences:

>Translated_257_residues
MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQ
LAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGF
VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTV
ARRLIEDTVAMCRAEYD
>Mature_257_residues
MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQ
LAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGF
VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTV
ARRLIEDTVAMCRAEYD

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=203, Percent_Identity=31.0344827586207, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI50593112, Length=170, Percent_Identity=34.1176470588235, Blast_Score=101, Evalue=6e-22,
Organism=Escherichia coli, GI48994995, Length=257, Percent_Identity=93.3852140077821, Blast_Score=501, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI212645999, Length=152, Percent_Identity=31.5789473684211, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71986510, Length=152, Percent_Identity=31.5789473684211, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321371, Length=176, Percent_Identity=32.3863636363636, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 29593; Mature: 29593

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQH
CCHHHHHHHCCCEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEH
RRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCR
HCCCHHHHHHHHHCCCCEEHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGFVEVGETLEQAVAREVMEESG
HHCCCCHHHHHEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTV
CEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECHHHHHHCCCEEECCCCCCCCCHHH
ARRLIEDTVAMCRAEYD
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQH
CCHHHHHHHCCCEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEH
RRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCR
HCCCHHHHHHHHHCCCCEEHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGFVEVGETLEQAVAREVMEESG
HHCCCCHHHHHEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTV
CEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECHHHHHHCCCEEECCCCCCCCCHHH
ARRLIEDTVAMCRAEYD
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA