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The map label for this gene is entD [H]

Identifier: 194735042

GI number: 194735042

Start: 714130

End: 714834

Strand: Reverse

Name: entD [H]

Synonym: SeSA_A0742

Alternate gene names: 194735042

Gene position: 714834-714130 (Counterclockwise)

Preceding gene: 194737055

Following gene: 194734677

Centisome position: 15.18

GC content: 56.03

Gene sequence:

>705_bases
ATGCGGACATCTCATTTTCCCCTTCCCTTTGCCGGACACAGGCTGCATATCGTCGACTTTGATGCGAGCAGCTTTCACGA
ACACGACCTGCTATGGCTTCCTCATCACGATCGGCTCCGGTCTGCCGGACGCAAGCGTAAAGCTGAACATCTGGCAGGCC
GCATTGCCGCCGTTCACGCGCTACGCGAGGTGGGCGTCAGGACAGTGCCCGGTATTGGCGACAAGCGACAGCCGCTATGG
CCGGACGGCCTATTTGGCAGCATCAGCCACTGTGCGTCAACGGCGCTGGCCGTCATATCCCGACAACGTGTCGGCGTTGA
TATAGAAAAAATCATGAGTCAGCACACGGCGACAGAGCTGGCGCCGTCCATTATCGATAGCGATGAGCACCAAATTCTCC
AGGCGAGCTCGCTCCCTTTTCCGCTTGCCCTGACGCTGGCCTTCTCCGCCAAAGAGAGCGTTTATAAAGCCTTTTCAGAC
CGCGTCACGCTCCCGGGATTCGATAGCGCAAAAGTTACCTCGCTTACCGCCACGCACATCTCGTTACATCTGCTGCCAGC
CTTTGCCGCCACGATGGCTGAACGTACCGTCCGTACAGAATGGTTTCAACGTGACAATAGCGTTATTACTCTTGTTTTTG
CAATAATGCGCTTTCCCCACGACAGGAGCGCTCCCGCTTCTATACTTAGCGCAATACCCCGATAA

Upstream 100 bases:

>100_bases
CCTATAACGAACCGGGACGTACGTGGTATATGAGCATTAATACCCATTTCTGATGGCAACCTTCCCTCCCTCATTCGGGG
GAGGGAATTAGCAAAAAACG

Downstream 100 bases:

>100_bases
ATGAGATCACTATGACGCTGAATGATTTTCACGTTTCTGAACCTTATACGCTTGGTATTGAGCTGGAGATGCAGGTGATC
AATCCACCTGGCTACGATTT

Product: phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex

Products: NA

Alternate protein names: Enterobactin synthase component D; Enterochelin synthase D [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRTVPGIGDKRQPLW
PDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATELAPSIIDSDEHQILQASSLPFPLALTLAFSAKESVYKAFSD
RVTLPGFDSAKVTSLTATHISLHLLPAFAATMAERTVRTEWFQRDNSVITLVFAIMRFPHDRSAPASILSAIPR

Sequences:

>Translated_234_residues
MRTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRTVPGIGDKRQPLW
PDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATELAPSIIDSDEHQILQASSLPFPLALTLAFSAKESVYKAFSD
RVTLPGFDSAKVTSLTATHISLHLLPAFAATMAERTVRTEWFQRDNSVITLVFAIMRFPHDRSAPASILSAIPR
>Mature_234_residues
MRTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRTVPGIGDKRQPLW
PDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATELAPSIIDSDEHQILQASSLPFPLALTLAFSAKESVYKAFSD
RVTLPGFDSAKVTSLTATHISLHLLPAFAATMAERTVRTEWFQRDNSVITLVFAIMRFPHDRSAPASILSAIPR

Specific function: Catalyzes the transfer of the 4'-phosphopantetheine moiety from coenzyme A to apo-domains of both entB (an ArCP domain) and entF (a PCP domain). Plays an essential role in the assembly of the enterobactin [H]

COG id: COG2977

COG function: function code Q; Phosphopantetheinyl transferase component of siderophore synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. EntD family [H]

Homologues:

Organism=Escherichia coli, GI1786797, Length=183, Percent_Identity=57.3770491803279, Blast_Score=212, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR003542 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: 2.7.8.-

Molecular weight: Translated: 25884; Mature: 25884

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREVGVRTVPGIGDKRQPLWPDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATEL
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
APSIIDSDEHQILQASSLPFPLALTLAFSAKESVYKAFSDRVTLPGFDSAKVTSLTATHI
HHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHH
SLHLLPAFAATMAERTVRTEWFQRDNSVITLVFAIMRFPHDRSAPASILSAIPR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MRTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREVGVRTVPGIGDKRQPLWPDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATEL
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
APSIIDSDEHQILQASSLPFPLALTLAFSAKESVYKAFSDRVTLPGFDSAKVTSLTATHI
HHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHH
SLHLLPAFAATMAERTVRTEWFQRDNSVITLVFAIMRFPHDRSAPASILSAIPR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]