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The map label for this gene is opuCB [H]

Identifier: 194734901

GI number: 194734901

Start: 1538721

End: 1539431

Strand: Reverse

Name: opuCB [H]

Synonym: SeSA_A1596

Alternate gene names: 194734901

Gene position: 1539431-1538721 (Counterclockwise)

Preceding gene: 194735439

Following gene: 194737639

Centisome position: 32.69

GC content: 54.57

Gene sequence:

>711_bases
ATGCACACCCTCACCCTAAAACGCGTACTTGGGTTCACTATCGTCATTTTGCTGTTACTGGCGCTGTTTATCTGGGGAAT
CGGTCTGGAGACGCTGAAAGCGCGTCAGGTCGATCTGCTGTATCTCGGACAACGGCATTTGATGCTGGTCTTTACGTCCA
TGTTTTTTGCTTTACTGGTCGGTATCCCGAGTGGGATTTTACTCAGCCGACCTGCGGCAAAAGGATTTGCTGAATATGTC
ATGCAAATCTTTAATGTTGGTAATACCTTGCCGCCACTGGCCGTCCTGGCCTTAGCGATGGTGATTATCGGGATCGGCGA
TACGCCCGCCATTGTCGCGCTATTTCTGGCCTCCCTTCTGCCTATCGTCCGCAATACCTATGCGGGCCTCTGTTCCGTTC
CCGCCTCACTGATTGAAGCGGCGAACGGGATTGGGATGACAAAATGGCAGCGGCTTCGCCAGGTAGAGCTACCTAATGCG
TGGCCAGTGATGCTGTCCGGTATTCGCATCGCGACCGCCATCAATGTCGGCACCGCGCCGCTGGCCTTTCTGATCGGCGC
CAGCAGCTACGGCGAGCTGATTTTCCCGGGAATTTATCTCAACGATTTTCCGACGTTGATCCTCGGCGCAACGGCCACGG
CGTTATTCGCGCTGATTCTTGACACTCTGCTTGCCTGGTTTGGGCGACGCCTTAGCCCTCATACCGTTTGA

Upstream 100 bases:

>100_bases
AACCTGTTGCTATAGCTCAAAGTACCCTGCCGGAACATGGCATAACAACACGCGACTCTTAACGTCGCCATAACACATGC
AAACAGGGAGACACACCGCA

Downstream 100 bases:

>100_bases
ACGCATAAATAACAATAAGGAGCGTTAAATGAGATTCAAAAAACACCTGTTAGGATGGCTTGCCGCAACGCTGTTGTTCA
GTAGCCAGACGCAGGCCGCG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MHTLTLKRVLGFTIVILLLLALFIWGIGLETLKARQVDLLYLGQRHLMLVFTSMFFALLVGIPSGILLSRPAAKGFAEYV
MQIFNVGNTLPPLAVLALAMVIIGIGDTPAIVALFLASLLPIVRNTYAGLCSVPASLIEAANGIGMTKWQRLRQVELPNA
WPVMLSGIRIATAINVGTAPLAFLIGASSYGELIFPGIYLNDFPTLILGATATALFALILDTLLAWFGRRLSPHTV

Sequences:

>Translated_236_residues
MHTLTLKRVLGFTIVILLLLALFIWGIGLETLKARQVDLLYLGQRHLMLVFTSMFFALLVGIPSGILLSRPAAKGFAEYV
MQIFNVGNTLPPLAVLALAMVIIGIGDTPAIVALFLASLLPIVRNTYAGLCSVPASLIEAANGIGMTKWQRLRQVELPNA
WPVMLSGIRIATAINVGTAPLAFLIGASSYGELIFPGIYLNDFPTLILGATATALFALILDTLLAWFGRRLSPHTV
>Mature_236_residues
MHTLTLKRVLGFTIVILLLLALFIWGIGLETLKARQVDLLYLGQRHLMLVFTSMFFALLVGIPSGILLSRPAAKGFAEYV
MQIFNVGNTLPPLAVLALAMVIIGIGDTPAIVALFLASLLPIVRNTYAGLCSVPASLIEAANGIGMTKWQRLRQVELPNA
WPVMLSGIRIATAINVGTAPLAFLIGASSYGELIFPGIYLNDFPTLILGATATALFALILDTLLAWFGRRLSPHTV

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=200, Percent_Identity=42.5, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1788451, Length=195, Percent_Identity=35.3846153846154, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789033, Length=175, Percent_Identity=30.8571428571429, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786564, Length=140, Percent_Identity=34.2857142857143, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25411; Mature: 25411

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLTLKRVLGFTIVILLLLALFIWGIGLETLKARQVDLLYLGQRHLMLVFTSMFFALLV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
GIPSGILLSRPAAKGFAEYVMQIFNVGNTLPPLAVLALAMVIIGIGDTPAIVALFLASLL
HCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
PIVRNTYAGLCSVPASLIEAANGIGMTKWQRLRQVELPNAWPVMLSGIRIATAINVGTAP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHCHHHHHHCCCCHHH
LAFLIGASSYGELIFPGIYLNDFPTLILGATATALFALILDTLLAWFGRRLSPHTV
HHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHTLTLKRVLGFTIVILLLLALFIWGIGLETLKARQVDLLYLGQRHLMLVFTSMFFALLV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
GIPSGILLSRPAAKGFAEYVMQIFNVGNTLPPLAVLALAMVIIGIGDTPAIVALFLASLL
HCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
PIVRNTYAGLCSVPASLIEAANGIGMTKWQRLRQVELPNAWPVMLSGIRIATAINVGTAP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHCHHHHHHCCCCHHH
LAFLIGASSYGELIFPGIYLNDFPTLILGATATALFALILDTLLAWFGRRLSPHTV
HHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]