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The map label for this gene is envR [H]

Identifier: 194734773

GI number: 194734773

Start: 3458234

End: 3458896

Strand: Reverse

Name: envR [H]

Synonym: SeSA_A3581

Alternate gene names: 194734773

Gene position: 3458896-3458234 (Counterclockwise)

Preceding gene: 194733966

Following gene: 194735259

Centisome position: 73.45

GC content: 43.74

Gene sequence:

>663_bases
ATGGCGAAGAAAACGAAGGCGGATGCGCTTAAAACGCGGCAACACTTGATTGAAACCGCTATTGCGCAGTTCGCTTTGCG
CGGCGTTGCCAACACGACGCTGAATGATATCGCTGATGCCGCTGATGTCACGCGGGGCGCCATCTACTGGCACTTTGAGA
ATAAAACGCAGTTGTTTAATGAGGTTTGGTTACAGCAACCACCTTTACGCGAACTTATTCAGGATAGGCTTACGGGATGC
TGGAATGATAATCCTTTACAGGATCTACGAGAGAAATTTATTGCAGCCTTACAATATATTGCGGCAGTGCCTCGTCAGCA
GGCATTAATGCAGATTTTATATCATAAATGTGAATTCCATAATGGTATGATATCGGAACAGGCCATTCGGGAGAAGATTG
GTTTCCATCATCAGTCGCTGCTTGAAGTATTACAGCGATGTATGGATAAAAAGCTGATCTCAGGCAGTCTTGATCTGGAT
GTCATATTAATTATTCTGCATGGTAGTTTTAGCGGAATAGTAAAGAACTGGTTAATGAATCCCACAAGTTATGATCTTTA
TAAGCAGGCGCCTGCATTAGTCGATAATGTATTAAAAATGCTAAGCCCGGATGGCAGTGTGAGGCAATTAATGCCAAATG
AACAACAGGCGGAAGAAGCCTGA

Upstream 100 bases:

>100_bases
CTGTCTCTCGTCTGACTAAAAAGGACATGGTAAAGTTGTTTTTTATGCTGAGTATTTTATCAGCGTATTTATCGTTTTTA
TGGTCCAGGATATCTTAATT

Downstream 100 bases:

>100_bases
GATTATTTTGAGTTGATATTATATATTGACCTTGTGAATATATTGGCAGGGTCCCGAATATCGCGAGCAATTTCCTCTGC
CGTACGCGGCTTGCCAAGCA

Product: DNA-binding transcriptional regulator EnvR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MAKKTKADALKTRQHLIETAIAQFALRGVANTTLNDIADAADVTRGAIYWHFENKTQLFNEVWLQQPPLRELIQDRLTGC
WNDNPLQDLREKFIAALQYIAAVPRQQALMQILYHKCEFHNGMISEQAIREKIGFHHQSLLEVLQRCMDKKLISGSLDLD
VILIILHGSFSGIVKNWLMNPTSYDLYKQAPALVDNVLKMLSPDGSVRQLMPNEQQAEEA

Sequences:

>Translated_220_residues
MAKKTKADALKTRQHLIETAIAQFALRGVANTTLNDIADAADVTRGAIYWHFENKTQLFNEVWLQQPPLRELIQDRLTGC
WNDNPLQDLREKFIAALQYIAAVPRQQALMQILYHKCEFHNGMISEQAIREKIGFHHQSLLEVLQRCMDKKLISGSLDLD
VILIILHGSFSGIVKNWLMNPTSYDLYKQAPALVDNVLKMLSPDGSVRQLMPNEQQAEEA
>Mature_219_residues
AKKTKADALKTRQHLIETAIAQFALRGVANTTLNDIADAADVTRGAIYWHFENKTQLFNEVWLQQPPLRELIQDRLTGCW
NDNPLQDLREKFIAALQYIAAVPRQQALMQILYHKCEFHNGMISEQAIREKIGFHHQSLLEVLQRCMDKKLISGSLDLDV
ILIILHGSFSGIVKNWLMNPTSYDLYKQAPALVDNVLKMLSPDGSVRQLMPNEQQAEEA

Specific function: Potential regulator protein for the acrEF/envCD genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789664, Length=211, Percent_Identity=68.2464454976303, Blast_Score=306, Evalue=5e-85,
Organism=Escherichia coli, GI1786669, Length=219, Percent_Identity=38.3561643835616, Blast_Score=147, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013572
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08361 TetR_C_2; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25079; Mature: 24948

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKTKADALKTRQHLIETAIAQFALRGVANTTLNDIADAADVTRGAIYWHFENKTQLFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHH
EVWLQQPPLRELIQDRLTGCWNDNPLQDLREKFIAALQYIAAVPRQQALMQILYHKCEFH
HHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
NGMISEQAIREKIGFHHQSLLEVLQRCMDKKLISGSLDLDVILIILHGSFSGIVKNWLMN
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCC
PTSYDLYKQAPALVDNVLKMLSPDGSVRQLMPNEQQAEEA
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHCCC
>Mature Secondary Structure 
AKKTKADALKTRQHLIETAIAQFALRGVANTTLNDIADAADVTRGAIYWHFENKTQLFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHH
EVWLQQPPLRELIQDRLTGCWNDNPLQDLREKFIAALQYIAAVPRQQALMQILYHKCEFH
HHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
NGMISEQAIREKIGFHHQSLLEVLQRCMDKKLISGSLDLDVILIILHGSFSGIVKNWLMN
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCC
PTSYDLYKQAPALVDNVLKMLSPDGSVRQLMPNEQQAEEA
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]