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The map label for this gene is yegS [H]

Identifier: 194734764

GI number: 194734764

Start: 2254662

End: 2255561

Strand: Direct

Name: yegS [H]

Synonym: SeSA_A2376

Alternate gene names: 194734764

Gene position: 2254662-2255561 (Clockwise)

Preceding gene: 194735950

Following gene: 194738317

Centisome position: 47.88

GC content: 55.33

Gene sequence:

>900_bases
ATGGCTAACTTTCCCGCCAGCTTACTGATACTCAATGGCAAAAGCGCTGATAACCAGCCGCTACGTGAGGCCATTACTCT
CCTTCGCGACGAAGGCATACAGATTCACGTTCGGGTAACCTGGGAAAAAGGCGACGCGCAGCGTTACGTTGATGAAGCCC
GTAGACTGGGCGTTGAAACGGTGATTGCCGGCGGCGGAGACGGTACCATTAATGAAGTGTCGACCGCGCTCATCCAGATC
CGCGACGGCGTAGCCCCTGCACTGGGCCTTTTGCCGCTCGGCACTGCCAACGATTTTGCCACCAGCGCCGGTATTCCTGA
AGCGCTGGACAAAGCGCTGAAACTGGCGATTGCCGGAAACGCGATGGAAATTGATATGGCCAGGGTCAATGATAAAACCT
GTTTTATCAATATGGCGACGGGCGGTTTTGGCACCCGCATTACCACTGAAACGCCGGAAAAACTCAAGGCCGCGTTGGGC
GGCGTCTCCTATCTTATCCACGGTCTGATGAGAATGGATACGCTGACCCCTGACCGCTGCGAAATACGTGGCGAAAACTT
TCACTGGCAGGGAGATGCGCTGGTGATCGGCATCGGCAACGGTCGTCAGGCCGGCGGCGGGCAGCAATTATGTCCCACCG
CGCTGATTAACGACGGACTGTTACAGCTACGGATTTTTACCGGCGAAGAGCTGCTGCCGGCGCTGTTTTCCACACTCACG
CAGTCAGATGACAATCCGAATATTATTGACGGCGCCTCGGCGTGGTTTGATATTCATGCGCCGCATGAAATCACGTTTAA
TCTGGATGGCGAACCACTCAGCGGACAAGAATTTCATATTGAGGTGCTACCTGGCGCATTACGCTGTCGGCTGCCGCCAG
ACTGCCCGTTGCTACGTTAA

Upstream 100 bases:

>100_bases
AGTGCGCAACATTTCAATTTTCATCCTGTTCTGACCTCGCTTTTTCATTTCTGCTATACACTTTCTGGAGATTGTTGTTC
AACCTATTAAGGCATAACGG

Downstream 100 bases:

>100_bases
TAACACCTGTCGCTGGCCGGATGCGCTCACATCCGGCTTTTCTTCGTTAAACTCAGGCGATGGTGACTTTGCTATCCAGA
TAGACATCCTGTACGGCGTT

Product: lipid kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVETVIAGGGDGTINEVSTALIQI
RDGVAPALGLLPLGTANDFATSAGIPEALDKALKLAIAGNAMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALG
GVSYLIHGLMRMDTLTPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPTALINDGLLQLRIFTGEELLPALFSTLT
QSDDNPNIIDGASAWFDIHAPHEITFNLDGEPLSGQEFHIEVLPGALRCRLPPDCPLLR

Sequences:

>Translated_299_residues
MANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVETVIAGGGDGTINEVSTALIQI
RDGVAPALGLLPLGTANDFATSAGIPEALDKALKLAIAGNAMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALG
GVSYLIHGLMRMDTLTPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPTALINDGLLQLRIFTGEELLPALFSTLT
QSDDNPNIIDGASAWFDIHAPHEITFNLDGEPLSGQEFHIEVLPGALRCRLPPDCPLLR
>Mature_298_residues
ANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVETVIAGGGDGTINEVSTALIQIR
DGVAPALGLLPLGTANDFATSAGIPEALDKALKLAIAGNAMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALGG
VSYLIHGLMRMDTLTPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPTALINDGLLQLRIFTGEELLPALFSTLTQ
SDDNPNIIDGASAWFDIHAPHEITFNLDGEPLSGQEFHIEVLPGALRCRLPPDCPLLR

Specific function: Probably phosphorylates lipids; the in vivo substrate is unknown [H]

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

Organism=Escherichia coli, GI1788402, Length=299, Percent_Identity=85.2842809364548, Blast_Score=525, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005218
- InterPro:   IPR001206
- InterPro:   IPR022433
- InterPro:   IPR022862 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: NA

Molecular weight: Translated: 32054; Mature: 31923

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVET
CCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCEEE
VIAGGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATSAGIPEALDKALKLAIAGN
EEECCCCCCHHHHHHHHHHHHCCCCCHHHEEECCCCCCHHHCCCCHHHHHHHHEEEECCC
AMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALGGVSYLIHGLMRMDTLTPDRC
EEEEEEEEECCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
EIRGENFHWQGDALVIGIGNGRQAGGGQQLCPTALINDGLLQLRIFTGEELLPALFSTLT
EECCCCEEEECCEEEEECCCCCCCCCCCCCCHHHHHCCCEEEEEEECCHHHHHHHHHHHH
QSDDNPNIIDGASAWFDIHAPHEITFNLDGEPLSGQEFHIEVLPGALRCRLPPDCPLLR
CCCCCCCEEECCCCEEEEECCCEEEEEECCCCCCCCEEEEEECCCEEEECCCCCCCCCC
>Mature Secondary Structure 
ANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVET
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCEEE
VIAGGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATSAGIPEALDKALKLAIAGN
EEECCCCCCHHHHHHHHHHHHCCCCCHHHEEECCCCCCHHHCCCCHHHHHHHHEEEECCC
AMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALGGVSYLIHGLMRMDTLTPDRC
EEEEEEEEECCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
EIRGENFHWQGDALVIGIGNGRQAGGGQQLCPTALINDGLLQLRIFTGEELLPALFSTLT
EECCCCEEEECCEEEEECCCCCCCCCCCCCCHHHHHCCCEEEEEEECCHHHHHHHHHHHH
QSDDNPNIIDGASAWFDIHAPHEITFNLDGEPLSGQEFHIEVLPGALRCRLPPDCPLLR
CCCCCCCEEECCCCEEEEECCCEEEEEECCCCCCCCEEEEEECCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA