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The map label for this gene is aslB [H]

Identifier: 194734759

GI number: 194734759

Start: 4050751

End: 4052094

Strand: Direct

Name: aslB [H]

Synonym: SeSA_A4174

Alternate gene names: 194734759

Gene position: 4050751-4052094 (Clockwise)

Preceding gene: 194737906

Following gene: 194735544

Centisome position: 86.02

GC content: 53.79

Gene sequence:

>1344_bases
TTGTCTCATGGCGCTGGTGAACCTTATTTTTTAACGGAGATGTCTGACATGGCGGTAGCAGGTTGTCACGTAATGACCAA
ACCCGGCGGCGCGATCTGCAATATTGATTGCACATATTGCTTCTATCTTGAAAAAGAGGCGCTGTACCCGGAACGCAATA
AAAACTGGCGAATGTCGGACGAGACGCTGGAACAGTTTATACGCCAGCATATTGCCGCGCAGAGTGGCGACCGCATTGAC
TTTGCCTGGCAGGGCGGCGAACCGACCATGATGGGGCTACCGTTTTTCCGCCGGGTTGTCGCATTATGTGAAAAGTACGG
CGATGGGCGAAAAATCACTCATGCGTTGCAGACGAACGGCATCCTGGTGAATGACGAGTGGGCGCGCTTTTTCGCTGAAC
AGCATTTTCTCATCGGTCTCTCTATCGACGGCCCGGCGTCGTTACACAACCACTATCGGCTTAATCGTGCTGGAAAAGGA
ACTCATGAACAGGTCGTCGCAGCAATGGCGCGGCTTAAAGCGCACCATGTCGACTTTAATACCTTAACCGTCGTGGGAAA
ACATAACGTCGGTCATGCAGCAGACGTCTACGAATTTCTTCTGGCGGCGGGATCGCGTTTTATTCAGTTTATCCCGCTGG
TGGAGCGAATGAGCACCGATAACTCATCGGTACTTAATCTGGTGATGCCCGGCGAAAGCGCGGCGACGCTGGCGCCATGG
ACGGTACCGTCGTGGCAATATGGCGAATTTCTCAACCAGATCTTTGATATCTGGGTTCGTCGCGACGTAGACCGCGTCTA
TGTGCAGATGTTTGACGTGGCGTTAGCCGCCTGGACGGCGCAGAAGCCGATACTGTGTGTGCATTCCGAGACTTGTGGAC
ATGCCTTCGCGTTGGAGTCGAACGGCGATCTCTACAACTGCGACCACTTTGTCTACCCGGAGCATCTGCTGGGGAATATC
CACCAGCACAGCATCAAAACCTTAAATAATAGCGAGCGGGCTATTGCGTTTGGCGAGGCCAAGCGGGAGACCCTGACCGC
CGATTGTCGTCGCTGTGACTACCGCTTTGCGTGTCATGGCGGCTGTCCGAAGCATCGCTTTGCCGTCTCGCCGTCCGGTC
ATCCTGCGCATAATTACTTGTGTGCGGGCTATAAGCATTTTTTCCAGCACGTTACGCCGTATATGAATGTCTGGCGGGAG
CTGCTGGCGCAAGGCTATCCGATGGCATCGATCATGCGCTGGCTGGCGCAGGACGCGCGTAAAGATACAGGAGCCGTCAG
TCGTAACCATCTCTGTCCCTGCGGCAGCGGCAAAAAATATAAAAAATGCTGTGGTAAAGCATAG

Upstream 100 bases:

>100_bases
CCTCGCAGATCGTTTTTCCTGTCATGATCGCCCAGCGCTCTCATAGCACAAAACGAGGTTTTCCATTCTGTTATGTTCCC
TGGCGACGGTAAACGTCGCA

Downstream 100 bases:

>100_bases
CTAACGTGGCGATGACGCTTTGTTGAGCCTACACCGACTCCGGTCTCGTAGGCCCAACAAACATCGTAATGCGCTGTGGT
TAGCCTTTTTTCCCACCGTA

Product: chondroitin sulfate/heparin utilization regulation protein

Products: NA

Alternate protein names: AnSME homolog [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSHGAGEPYFLTEMSDMAVAGCHVMTKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSDETLEQFIRQHIAAQSGDRID
FAWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNGILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRLNRAGKG
THEQVVAAMARLKAHHVDFNTLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPW
TVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQKPILCVHSETCGHAFALESNGDLYNCDHFVYPEHLLGNI
HQHSIKTLNNSERAIAFGEAKRETLTADCRRCDYRFACHGGCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWRE
LLAQGYPMASIMRWLAQDARKDTGAVSRNHLCPCGSGKKYKKCCGKA

Sequences:

>Translated_447_residues
MSHGAGEPYFLTEMSDMAVAGCHVMTKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSDETLEQFIRQHIAAQSGDRID
FAWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNGILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRLNRAGKG
THEQVVAAMARLKAHHVDFNTLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPW
TVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQKPILCVHSETCGHAFALESNGDLYNCDHFVYPEHLLGNI
HQHSIKTLNNSERAIAFGEAKRETLTADCRRCDYRFACHGGCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWRE
LLAQGYPMASIMRWLAQDARKDTGAVSRNHLCPCGSGKKYKKCCGKA
>Mature_446_residues
SHGAGEPYFLTEMSDMAVAGCHVMTKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSDETLEQFIRQHIAAQSGDRIDF
AWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNGILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRLNRAGKGT
HEQVVAAMARLKAHHVDFNTLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPWT
VPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQKPILCVHSETCGHAFALESNGDLYNCDHFVYPEHLLGNIH
QHSIKTLNNSERAIAFGEAKRETLTADCRRCDYRFACHGGCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWREL
LAQGYPMASIMRWLAQDARKDTGAVSRNHLCPCGSGKKYKKCCGKA

Specific function: Potential Positive Factor For The Regulation Of Arylsulfatase. [C]

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=393, Percent_Identity=47.8371501272265, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI87081923, Length=392, Percent_Identity=41.8367346938776, Blast_Score=339, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 50385; Mature: 50254

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHGAGEPYFLTEMSDMAVAGCHVMTKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSD
CCCCCCCCEEEECHHHHHHCCEEEEECCCCEEEEEEEEEEEEEEHHCCCCCCCCCCCCCH
ETLEQFIRQHIAAQSGDRIDFAWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNG
HHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHCCCCCCEEHHHHCCC
ILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRLNRAGKGTHEQVVAAMARLKAHHVDFN
EEECHHHHHHHHCCEEEEEEECCCCHHHHHCEEECCCCCCHHHHHHHHHHHHHHHCCCCE
TLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPW
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCC
TVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQKPILCVHSETCGHAFALES
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECC
NGDLYNCDHFVYPEHLLGNIHQHSIKTLNNSERAIAFGEAKRETLTADCRRCDYRFACHG
CCCEECCCCCCCHHHHHCCHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCEEEECC
GCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWRELLAQGYPMASIMRWLAQDAR
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KDTGAVSRNHLCPCGSGKKYKKCCGKA
HCCCCCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SHGAGEPYFLTEMSDMAVAGCHVMTKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSD
CCCCCCCEEEECHHHHHHCCEEEEECCCCEEEEEEEEEEEEEEHHCCCCCCCCCCCCCH
ETLEQFIRQHIAAQSGDRIDFAWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNG
HHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHCCCCCCEEHHHHCCC
ILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRLNRAGKGTHEQVVAAMARLKAHHVDFN
EEECHHHHHHHHCCEEEEEEECCCCHHHHHCEEECCCCCCHHHHHHHHHHHHHHHCCCCE
TLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPW
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCC
TVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQKPILCVHSETCGHAFALES
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECC
NGDLYNCDHFVYPEHLLGNIHQHSIKTLNNSERAIAFGEAKRETLTADCRRCDYRFACHG
CCCEECCCCCCCHHHHHCCHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCEEEECC
GCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWRELLAQGYPMASIMRWLAQDAR
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KDTGAVSRNHLCPCGSGKKYKKCCGKA
HCCCCCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 11222759 [H]