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The map label for this gene is aaeA [H]

Identifier: 194734710

GI number: 194734710

Start: 3430175

End: 3431107

Strand: Reverse

Name: aaeA [H]

Synonym: SeSA_A3557

Alternate gene names: 194734710

Gene position: 3431107-3430175 (Counterclockwise)

Preceding gene: 194738135

Following gene: 194737497

Centisome position: 72.86

GC content: 56.16

Gene sequence:

>933_bases
GTGAAAACACTAACAAGAAAACTCTCCCGTACGGCCATTACCCTCGTACTGGTTATTCTGGCCTTTATCGCCATTTTCCG
CGCCTGGGTGTATTACACCGAATCTCCCTGGACGCGCGACGCGCGTTTTAGCGCCGATGTCGTCGCTATTGCCCCGGATG
TCGCGGGCCTGATTACCCATGTAAACGTGCATGATAACCAACTGGTGAAAAAGGATCAGGTCCTGTTTACCATCGATCAG
CCACGCTATCAAAAAGCGCTGGCGGAAGCGGAAGCTGATGTAGCCTATTATCAGGTCCTGGCGCAGGAAAAACGCCAGGA
AGCCAGTCGCCGTAATCGCCTCGGCGTACAGGCGATGTCCCGGGAAGAGATCGATCAGGCGAACAATGTTTTGCAGACTG
TACTGCATCAACTGGCTAAAGCCCAGGCGACGCGCGATCTGGCTAAACTCGATCTGGAACGCACCGTCATTCGCGCGCCT
GCCGACGGCTGGGTGACTAACCTCAATGTTTATGCCGGTGAATTTATTACCCGCGGTTCCACAGCCGTCGCCCTGGTGAA
AAAGAACTCTTTTTACGTGCAGGCCTATATGGAAGAGACCAAGCTGGAAGGCGTGCGTCCGGGATATCGTGCCGAAATCA
CGCCGCTTGGCAGTAACCGGGTATTAAAAGGTACCGTCGATAGCGTGGCGGCAGGGGTAACGAATGCCAGCAGTACCAGC
GATGCGAAAGGGATGGCGACGATAGACTCTAACCTCGAATGGGTGCGTCTGGCCCAGCGTGTCCCGGTGCGCATCCGGCT
CGACGAGCAGCAGGGGAATTTGTGGCCTGCCGGTACGACGGCAACCGTCGTGATCACCGGTAAGCAGGATCGTGACGCAA
GCCAGGACTCCTTCTTCCGTAAACTGGCGCACCGGCTGCGCGAATTCGGTTAA

Upstream 100 bases:

>100_bases
ACGGGCATCTATGATTTTGTCTGGCATCCGGCTCTGTTCAATACCGCGCTGTATTGTTGTCTGTTTTATTTAATATCGCG
CCTGTTCGTTTGAGGTTGAA

Downstream 100 bases:

>100_bases
TCGTCATGGGCATTTTCTCCATTGCCAACCAGCACATTCGTTTTGCGGTAAAGCTGGCGTGCGCCATTGTGCTGGCATTA
TTTATCGGCTTCCATTTTCA

Product: p-hydroxybenzoic acid efflux subunit AaeA

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITHVNVHDNQLVKKDQVLFTIDQ
PRYQKALAEAEADVAYYQVLAQEKRQEASRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
ADGWVTNLNVYAGEFITRGSTAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSVAAGVTNASSTS
DAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWPAGTTATVVITGKQDRDASQDSFFRKLAHRLREFG

Sequences:

>Translated_310_residues
MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITHVNVHDNQLVKKDQVLFTIDQ
PRYQKALAEAEADVAYYQVLAQEKRQEASRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
ADGWVTNLNVYAGEFITRGSTAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSVAAGVTNASSTS
DAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWPAGTTATVVITGKQDRDASQDSFFRKLAHRLREFG
>Mature_310_residues
MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITHVNVHDNQLVKKDQVLFTIDQ
PRYQKALAEAEADVAYYQVLAQEKRQEASRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
ADGWVTNLNVYAGEFITRGSTAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSVAAGVTNASSTS
DAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWPAGTTATVVITGKQDRDASQDSFFRKLAHRLREFG

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789637, Length=310, Percent_Identity=92.5806451612903, Blast_Score=590, Evalue=1e-170,
Organism=Escherichia coli, GI87081951, Length=273, Percent_Identity=39.9267399267399, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1790519, Length=301, Percent_Identity=28.9036544850498, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788711, Length=310, Percent_Identity=25.4838709677419, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789041, Length=288, Percent_Identity=25.6944444444444, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 34576; Mature: 34576

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHEE
VNVHDNQLVKKDQVLFTIDQPRYQKALAEAEADVAYYQVLAQEKRQEASRRNRLGVQAMS
ECCCCCHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
REEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYAGEFITRGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECHHEECCC
TAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSVAAGVTNASSTS
EEEEEEECCCEEEEEEHHHHHCCCCCCCCCEEEEECCCCCEEECCHHHHHHCCCCCCCCC
DAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWPAGTTATVVITGKQDRDASQDSFFR
CCCCEEEECCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHH
KLAHRLREFG
HHHHHHHHCC
>Mature Secondary Structure
MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHEE
VNVHDNQLVKKDQVLFTIDQPRYQKALAEAEADVAYYQVLAQEKRQEASRRNRLGVQAMS
ECCCCCHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
REEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYAGEFITRGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECHHEECCC
TAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSVAAGVTNASSTS
EEEEEEECCCEEEEEEHHHHHCCCCCCCCCEEEEECCCCCEEECCHHHHHHCCCCCCCCC
DAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWPAGTTATVVITGKQDRDASQDSFFR
CCCCEEEECCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHH
KLAHRLREFG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA