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The map label for this gene is dcuC [H]

Identifier: 194734549

GI number: 194734549

Start: 763717

End: 765147

Strand: Reverse

Name: dcuC [H]

Synonym: SeSA_A0786

Alternate gene names: 194734549

Gene position: 765147-763717 (Counterclockwise)

Preceding gene: 194736545

Following gene: 194734902

Centisome position: 16.25

GC content: 53.6

Gene sequence:

>1431_bases
GTGGTTCTTATTTTTACTCTGGGTGTCGATAAGACAGGGGAAACAATGCTAACAGTTATAGAGCTCCTTATCGGAGTCGT
CGTTATTGTGGGTGTAGCGCGCTACATCATTAAGGGATATTCCGCCACTGGCGTTTTATTTGTCGGCGGTCTGGTTCTGC
TTATTATCAGCGCACTGATGGGGCATAAGGTATTACCTGCCAGCGAAACCAGTACCGGCTATACCGCAACAGATATTGTT
GAATACATCAAAATTTTGCTCATGAGTCGCGGCGGCGATCTTGGCATGATGATCATGATGCTGTGCGGCTTTGCCGCTTA
TATGACGCATATCGGCGCGAATGATATGGTCGTGAAGCTGGCGTCGAAACCTTTACAGTACATAAACTCGCCCTACCTGT
TGATGATTGCCGCCTATTTTGTCGCCTGCCTGATGTCGCTGGCCGTCTCTTCCGCGACGGGGCTTGGCGTACTGCTCATG
GCTACTCTCTTCCCGGTGATGGTCAACGTCGGCATTAGCCGCGGCGCGGCGGCGGCTATTTGCGCCTCTCCGGCCGCCAT
CATCCTCTCGCCAACGTCTGGCGATGTGGTTTTAGCCGCAAAAGCGGCGGAGATGCCGTTAATCGATTTCGCGTTCAAAA
CCACGCTGCCGATTTCCATCGCCGCAATTATCGGTATGGCGATTGCGCACTTTTTCTGGCAACGCTATCTGGATAAAAAA
GAGAACATTTCACATGAGATGCTGGACGTTGCGGAGATTACCACCACGGCCCCGGCGTTTTATGCCCTTTTGCCGTTCAC
GCCCATTATCGGCGTACTGATTTTTGACGGTAAATGGGGGCCGCAGTTGCACATTATTACCATCCTGGTGATCTGTATGC
TGCTGGCCGCCGTGCTGGAATTCGTGCGCGGCTTCAACACGCAAAATGTGTTTTCCGGCCTGGAAGTGGCTTATCGCGGC
ATGGCGGATGCGTTTGCCGGCGTCGTGATGCTGCTGGTCGCGGCGGGCGTTTTCGCCCAGGGGCTGAGCACCATTGGCTT
TATCCAAAGTCTGATCTCGATTGCCACTTCTTTTGGCTCCGCCAGCATTATTCTGATGCTGGTATTAGTGATTTTAACCA
TGCTGGCCGCGATGACCACCGGTTCAGGCAATGCGCCTTTTTACGCCTTTGTTGAGATGATCCCTAAATTGGCGCACTCC
TCCGGCATCAACCCAGCCTATTTATCCATCCCAATGCTGCAAGCCTCAAACCTGGGGCGCACGATTTCGCCGGTCTCCGG
CGTGGTGGTCGCTGTCGCCGGGATGGCTAAAATATCACCGTTTGAAGTGGTGAAGCGCACGTCCGTTCCGGTCATCGTCG
GTCTGTTGATCGTCATTATCGCCACGGAAATTATGGTGCCAGGCGCCTCTTCCGCCGTTACTGGCGGCTGA

Upstream 100 bases:

>100_bases
AGCATATTTCATCTTTAGCGATGACATGAAAAAATAACCGCGCCGTGATTTTAATCAGTAAGGCGCCATCCTTTATTCGG
TACATTTTTATACCACTTTT

Downstream 100 bases:

>100_bases
TAGCCAGTAAGCCGGGGCGAGGGAAAACGTCGCCCCGGCATCTTAAACCAAGCTTAGCCGCCGTGGTAAATACGCTGCGG
CCTGCCCACTTTGCCATGAA

Product: C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MVLIFTLGVDKTGETMLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALMGHKVLPASETSTGYTATDIV
EYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLM
ATLFPVMVNVGISRGAAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKK
ENISHEMLDVAEITTTAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFNTQNVFSGLEVAYRG
MADAFAGVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHS
SGINPAYLSIPMLQASNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG

Sequences:

>Translated_476_residues
MVLIFTLGVDKTGETMLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALMGHKVLPASETSTGYTATDIV
EYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLM
ATLFPVMVNVGISRGAAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKK
ENISHEMLDVAEITTTAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFNTQNVFSGLEVAYRG
MADAFAGVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHS
SGINPAYLSIPMLQASNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG
>Mature_476_residues
MVLIFTLGVDKTGETMLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALMGHKVLPASETSTGYTATDIV
EYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLM
ATLFPVMVNVGISRGAAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKK
ENISHEMLDVAEITTTAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFNTQNVFSGLEVAYRG
MADAFAGVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHS
SGINPAYLSIPMLQASNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=460, Percent_Identity=93.0434782608696, Blast_Score=722, Evalue=0.0,
Organism=Escherichia coli, GI1789622, Length=447, Percent_Identity=35.7941834451902, Blast_Score=277, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 49803; Mature: 49803

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLIFTLGVDKTGETMLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALM
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GHKVLPASETSTGYTATDIVEYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
ASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
CASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKK
HCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHH
ENISHEMLDVAEITTTAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
FVRGFNTQNVFSGLEVAYRGMADAFAGVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQASNLGR
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEHHHHCCCCC
TISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG
CCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVLIFTLGVDKTGETMLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALM
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GHKVLPASETSTGYTATDIVEYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
ASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
CASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKK
HCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHH
ENISHEMLDVAEITTTAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
FVRGFNTQNVFSGLEVAYRGMADAFAGVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQASNLGR
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEHHHHCCCCC
TISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG
CCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]