| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is pbpC [H]
Identifier: 194734438
GI number: 194734438
Start: 2667660
End: 2669975
Strand: Reverse
Name: pbpC [H]
Synonym: SeSA_A2770
Alternate gene names: 194734438
Gene position: 2669975-2667660 (Counterclockwise)
Preceding gene: 194734819
Following gene: 194736122
Centisome position: 56.7
GC content: 61.01
Gene sequence:
>2316_bases ATGAACGGTTGGCGTGGTAAACGTGACCGCTGGCTGTGGCTGGCGGGCGCGCCGCTTTTTATTTTCCTGGCGTTATGGGC GGCGGATAAACTCTGGCCGCTGCCGCTCAATGAGGTCCATCCTGCGCGGGTCGTGGTAGCCCATGACGGTACGCCGCTGT GGCGCTTTGCCGACGCCGGGGGGATCTGGCGTTATCCGGTGACGATTGAAGAGGTCTCTCCCCGTTACCTGGAGGCCTTA ATCAATTACGAAGATCGCTGGTTCTGGCGGCACCCTGGCGTTAACCCTTTCTCCGTCGCGCGCGCGGCATGGCAGGATCT TACCGCCGGGCGCGTTATTTCCGGCGGCAGTACGCTGACTATGCAGGTGGCGAGACTGCTGGACCCACATTCGCGCACGT TCGGCGGTAAAATCCGCCAGCTTTGGCGCGCCCTCCAGCTTGAATGGCATTTGTCCAAGCGCGATATCCTGACGCTGTAC CTGAACCGCGCGCCGTTCGGCGGCACGCTACAGGGTATTGGCGCTGCAAGCTGGGCCTACTTCGGCAAGCCGCCCGCGCG CCTGAGTTACGCTGACGCGGCGCTGCTGGCCGTATTGCCGCAGGCGCCGAGCCGGTTACGCCCCGACCGCTGGCCTGCGA GAGCCGAAGCGGCACGAAATAAAGTGCTGGATCGGATGGCGGCGCAGGGCGTCTGGCCTGCCGAAACGGTACGCGAGTCG CGTGAAGAGCCGGTCTGGCTGGCGCCGCGTCAAATGCCGCAACTGGCGCCGCTTTTTGCCCGAATGATGTTGAGTAAAAG CCAGAACGACAAAATTGTGACCACGCTGGACGCCGGGTTGCAGCGGCAACTGGAAGATCTGGCGCGGGCATGGAAAGGGC GGCTGCCGGCACGCAGTTCGTTGGCGATGATCGTCGTCGATCATACCGATATGAGCGTGCGCGGCTGGGTAGGATCGGTA GACCTTAATGACGACAGCCGTTTTGGTCATGTCGACATGGTAACGGCGATCCGATCGCCGGGATCGGTACTCAAACCCTT TGTGTACGGTCTGGCGCTGGATGACGGCTTGATCCATCCCGCATCATTATTACAGGACGTTCCGCGCCGCACCGGAGATT ACCGCCCGGGAAACTTCGACAGCGGATTTCACGGCCCGGTCAGCATGAGCGACGCGCTGGTACGCTCGCTGAATCTGCCT GCCGTTCAGGTGCTTGAAGTCTATGGGCCGAAACGATTTGCGGCAAAACTGCGTAACGTCGGCCTGCCGCTATATTTGCC TGCTGGCGCGGTGCCCAATCTTTCGCTGATTTTGGGCGGCGCGGGCGCGCGGCTTGACGAGATGGCGGCGGCATACAGCG CGTTCGCTCGTCATGGGAAAGCGGCGAAACTACGGTTACAGCCGGACGATCCGCTGTCGGAAAGACCATTAATGTCGCCG GGAGCGGCGTGGATCATTCGACGGATTATGGCGGATGAAGCGCAACCCTTGCCGGATAACGCGCTGCCGCGCATTGTGCC GTTGGCGTGGAAAACCGGCACCAGCTACGGCTATCGCGATGCGTGGGCTATTGGCGTTAACGCGCGCTATATCATCGGTA TCTGGACAGGCAGGCCCGACGGCACGCCTGTGGTGGGGCAATTTGGTTTTGCCAGCGCGGTGCCATTGCTTAACCAGGTC AATAATCTGTTACTGGCGCATACGGGACGCCTGCCGGAAGATCCGCGTCCGCAGACGGTAAGCCGCGGCGTCATTTGCTG GCCGGGCGGACAGACTCTGCCTGCCGGAGACAGCAACTGTCGCCGCCGACTGGCGACATGGCTTCTCGATGACAGCCAGC CGCCCACGCTGCTGTTACCTGAGCAGGAAGACATCAACGGTATTCGTTTCCCGGTCTGGCTGGATGATACGGGGCGGCGT GTCGCTGCCGACTGTCCGCAGGCGCGTGCGCATACGTTTATCGTCTGGCCGCGGCCGCTGGAGCCGTGGCTGCCGCCTGC GGAAAGACGTAGCGCCCGCTTGCCAGCGGCGTCCGACCACTGTCCGCCGCTGCAGGGCAATGATGCCGCGCCGTTAATGC TGTCAGGAGTGAGGGATGGCGCGGTGATCAGGCAATTGCCAGGCCAGGAAAACGTCACGCTGCCCGTCTCGACTACCGGC GGTAAAGGGCGTCGCTGGTGGTTTTTAAATGGCGAACCTGTTAATGGCGAAAATAATCGTCTTTCTTTATTACTCAATAT CGCTGGACGTTATCAACTTGTCGTAATGGATGAGTCCGGTCAGGTTGCAGCGGTTAATTTTGAATTAATACGTTAA
Upstream 100 bases:
>100_bases GGGGACGTACCAGCTTGCGCAACCGCAGGTGGAATCGATGTACGTGCCTCAGTGGCGGGCAACCGGCGCGAGCGAGGGGC TGCTGATTGTGACGCCTTAA
Downstream 100 bases:
>100_bases CAACTCTTCAGAATAAATTATGAATTTCATTTAATTTAAAGTTAATGAGAATTATTAATTTTCCGGAATTACCCTTAATG AGGGAGCTTGATAAATATCA
Product: penicillin-binding protein 1C
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 771; Mature: 771
Protein sequence:
>771_residues MNGWRGKRDRWLWLAGAPLFIFLALWAADKLWPLPLNEVHPARVVVAHDGTPLWRFADAGGIWRYPVTIEEVSPRYLEAL INYEDRWFWRHPGVNPFSVARAAWQDLTAGRVISGGSTLTMQVARLLDPHSRTFGGKIRQLWRALQLEWHLSKRDILTLY LNRAPFGGTLQGIGAASWAYFGKPPARLSYADAALLAVLPQAPSRLRPDRWPARAEAARNKVLDRMAAQGVWPAETVRES REEPVWLAPRQMPQLAPLFARMMLSKSQNDKIVTTLDAGLQRQLEDLARAWKGRLPARSSLAMIVVDHTDMSVRGWVGSV DLNDDSRFGHVDMVTAIRSPGSVLKPFVYGLALDDGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPVSMSDALVRSLNLP AVQVLEVYGPKRFAAKLRNVGLPLYLPAGAVPNLSLILGGAGARLDEMAAAYSAFARHGKAAKLRLQPDDPLSERPLMSP GAAWIIRRIMADEAQPLPDNALPRIVPLAWKTGTSYGYRDAWAIGVNARYIIGIWTGRPDGTPVVGQFGFASAVPLLNQV NNLLLAHTGRLPEDPRPQTVSRGVICWPGGQTLPAGDSNCRRRLATWLLDDSQPPTLLLPEQEDINGIRFPVWLDDTGRR VAADCPQARAHTFIVWPRPLEPWLPPAERRSARLPAASDHCPPLQGNDAAPLMLSGVRDGAVIRQLPGQENVTLPVSTTG GKGRRWWFLNGEPVNGENNRLSLLLNIAGRYQLVVMDESGQVAAVNFELIR
Sequences:
>Translated_771_residues MNGWRGKRDRWLWLAGAPLFIFLALWAADKLWPLPLNEVHPARVVVAHDGTPLWRFADAGGIWRYPVTIEEVSPRYLEAL INYEDRWFWRHPGVNPFSVARAAWQDLTAGRVISGGSTLTMQVARLLDPHSRTFGGKIRQLWRALQLEWHLSKRDILTLY LNRAPFGGTLQGIGAASWAYFGKPPARLSYADAALLAVLPQAPSRLRPDRWPARAEAARNKVLDRMAAQGVWPAETVRES REEPVWLAPRQMPQLAPLFARMMLSKSQNDKIVTTLDAGLQRQLEDLARAWKGRLPARSSLAMIVVDHTDMSVRGWVGSV DLNDDSRFGHVDMVTAIRSPGSVLKPFVYGLALDDGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPVSMSDALVRSLNLP AVQVLEVYGPKRFAAKLRNVGLPLYLPAGAVPNLSLILGGAGARLDEMAAAYSAFARHGKAAKLRLQPDDPLSERPLMSP GAAWIIRRIMADEAQPLPDNALPRIVPLAWKTGTSYGYRDAWAIGVNARYIIGIWTGRPDGTPVVGQFGFASAVPLLNQV NNLLLAHTGRLPEDPRPQTVSRGVICWPGGQTLPAGDSNCRRRLATWLLDDSQPPTLLLPEQEDINGIRFPVWLDDTGRR VAADCPQARAHTFIVWPRPLEPWLPPAERRSARLPAASDHCPPLQGNDAAPLMLSGVRDGAVIRQLPGQENVTLPVSTTG GKGRRWWFLNGEPVNGENNRLSLLLNIAGRYQLVVMDESGQVAAVNFELIR >Mature_771_residues MNGWRGKRDRWLWLAGAPLFIFLALWAADKLWPLPLNEVHPARVVVAHDGTPLWRFADAGGIWRYPVTIEEVSPRYLEAL INYEDRWFWRHPGVNPFSVARAAWQDLTAGRVISGGSTLTMQVARLLDPHSRTFGGKIRQLWRALQLEWHLSKRDILTLY LNRAPFGGTLQGIGAASWAYFGKPPARLSYADAALLAVLPQAPSRLRPDRWPARAEAARNKVLDRMAAQGVWPAETVRES REEPVWLAPRQMPQLAPLFARMMLSKSQNDKIVTTLDAGLQRQLEDLARAWKGRLPARSSLAMIVVDHTDMSVRGWVGSV DLNDDSRFGHVDMVTAIRSPGSVLKPFVYGLALDDGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPVSMSDALVRSLNLP AVQVLEVYGPKRFAAKLRNVGLPLYLPAGAVPNLSLILGGAGARLDEMAAAYSAFARHGKAAKLRLQPDDPLSERPLMSP GAAWIIRRIMADEAQPLPDNALPRIVPLAWKTGTSYGYRDAWAIGVNARYIIGIWTGRPDGTPVVGQFGFASAVPLLNQV NNLLLAHTGRLPEDPRPQTVSRGVICWPGGQTLPAGDSNCRRRLATWLLDDSQPPTLLLPEQEDINGIRFPVWLDDTGRR VAADCPQARAHTFIVWPRPLEPWLPPAERRSARLPAASDHCPPLQGNDAAPLMLSGVRDGAVIRQLPGQENVTLPVSTTG GKGRRWWFLNGEPVNGENNRLSLLLNIAGRYQLVVMDESGQVAAVNFELIR
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=763, Percent_Identity=81.7824377457405, Blast_Score=1279, Evalue=0.0, Organism=Escherichia coli, GI87082258, Length=249, Percent_Identity=34.136546184739, Blast_Score=127, Evalue=3e-30, Organism=Escherichia coli, GI1786343, Length=515, Percent_Identity=28.1553398058252, Blast_Score=122, Evalue=1e-28, Organism=Escherichia coli, GI1789601, Length=144, Percent_Identity=34.7222222222222, Blast_Score=67, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 85250; Mature: 85250
Theoretical pI: Translated: 10.21; Mature: 10.21
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNGWRGKRDRWLWLAGAPLFIFLALWAADKLWPLPLNEVHPARVVVAHDGTPLWRFADAG CCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCC GIWRYPVTIEEVSPRYLEALINYEDRWFWRHPGVNPFSVARAAWQDLTAGRVISGGSTLT CEEECCEEHHHCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEECCCCHHH MQVARLLDPHSRTFGGKIRQLWRALQLEWHLSKRDILTLYLNRAPFGGTLQGIGAASWAY HHHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCCCCCCCCCCCCHH FGKPPARLSYADAALLAVLPQAPSRLRPDRWPARAEAARNKVLDRMAAQGVWPAETVRES CCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHC REEPVWLAPRQMPQLAPLFARMMLSKSQNDKIVTTLDAGLQRQLEDLARAWKGRLPARSS CCCCEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCC LAMIVVDHTDMSVRGWVGSVDLNDDSRFGHVDMVTAIRSPGSVLKPFVYGLALDDGLIHP EEEEEEECCCCEEECEEEEEECCCCCCCCCEEEHHHHCCCCHHHHHHHHHEEECCCCCCH ASLLQDVPRRTGDYRPGNFDSGFHGPVSMSDALVRSLNLPAVQVLEVYGPKRFAAKLRNV HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHC GLPLYLPAGAVPNLSLILGGAGARLDEMAAAYSAFARHGKAAKLRLQPDDPLSERPLMSP CCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC GAAWIIRRIMADEAQPLPDNALPRIVPLAWKTGTSYGYRDAWAIGVNARYIIGIWTGRPD CHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCEEEEEEEECCCC GTPVVGQFGFASAVPLLNQVNNLLLAHTGRLPEDPRPQTVSRGVICWPGGQTLPAGDSNC CCCEEECCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHCCCEEECCCCCCCCCCCHHH RRRLATWLLDDSQPPTLLLPEQEDINGIRFPVWLDDTGRRVAADCPQARAHTFIVWPRPL HHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEECCCC EPWLPPAERRSARLPAASDHCPPLQGNDAAPLMLSGVRDGAVIRQLPGQENVTLPVSTTG CCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCCEEEEEECCC GKGRRWWFLNGEPVNGENNRLSLLLNIAGRYQLVVMDESGQVAAVNFELIR CCCCEEEEECCCCCCCCCCEEEEEEEECCCEEEEEECCCCCEEEEEEEEEC >Mature Secondary Structure MNGWRGKRDRWLWLAGAPLFIFLALWAADKLWPLPLNEVHPARVVVAHDGTPLWRFADAG CCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCC GIWRYPVTIEEVSPRYLEALINYEDRWFWRHPGVNPFSVARAAWQDLTAGRVISGGSTLT CEEECCEEHHHCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEECCCCHHH MQVARLLDPHSRTFGGKIRQLWRALQLEWHLSKRDILTLYLNRAPFGGTLQGIGAASWAY HHHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCCCCCCCCCCCCHH FGKPPARLSYADAALLAVLPQAPSRLRPDRWPARAEAARNKVLDRMAAQGVWPAETVRES CCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHC REEPVWLAPRQMPQLAPLFARMMLSKSQNDKIVTTLDAGLQRQLEDLARAWKGRLPARSS CCCCEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCC LAMIVVDHTDMSVRGWVGSVDLNDDSRFGHVDMVTAIRSPGSVLKPFVYGLALDDGLIHP EEEEEEECCCCEEECEEEEEECCCCCCCCCEEEHHHHCCCCHHHHHHHHHEEECCCCCCH ASLLQDVPRRTGDYRPGNFDSGFHGPVSMSDALVRSLNLPAVQVLEVYGPKRFAAKLRNV HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHC GLPLYLPAGAVPNLSLILGGAGARLDEMAAAYSAFARHGKAAKLRLQPDDPLSERPLMSP CCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC GAAWIIRRIMADEAQPLPDNALPRIVPLAWKTGTSYGYRDAWAIGVNARYIIGIWTGRPD CHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCEEEEEEEECCCC GTPVVGQFGFASAVPLLNQVNNLLLAHTGRLPEDPRPQTVSRGVICWPGGQTLPAGDSNC CCCEEECCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHCCCEEECCCCCCCCCCCHHH RRRLATWLLDDSQPPTLLLPEQEDINGIRFPVWLDDTGRRVAADCPQARAHTFIVWPRPL HHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEECCCC EPWLPPAERRSARLPAASDHCPPLQGNDAAPLMLSGVRDGAVIRQLPGQENVTLPVSTTG CCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCCEEEEEECCC GKGRRWWFLNGEPVNGENNRLSLLLNIAGRYQLVVMDESGQVAAVNFELIR CCCCEEEEECCCCCCCCCCEEEEEEEECCCEEEEEECCCCCEEEEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]