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The map label for this gene is tcp [H]

Identifier: 194734389

GI number: 194734389

Start: 3628798

End: 3630441

Strand: Direct

Name: tcp [H]

Synonym: SeSA_A3769

Alternate gene names: 194734389

Gene position: 3628798-3630441 (Clockwise)

Preceding gene: 194736064

Following gene: 194737663

Centisome position: 77.06

GC content: 55.6

Gene sequence:

>1644_bases
ATGAAAAATATCAAAGTCATCACCGGCGTTATCGCGACGCTGGGCATATTTAGCGCCTTATTGCTGGTGACAGGAATACT
GTTTTATTCCGCCGTCAGCAGCGATCGGCTGAATTTCCAGAATGCGAGCGCGCTGAGTTACCAACAACAGGAACTGGGCG
GCAGTTTTCAGACATTGATCGAAACCCGCGTCACCATTAACCGCGTGGCGATACGCATGTTAAAAAATCAGCGCGATCCC
GCCTCGCTGGACGCCATGAACACGCTGTTAACCAACGCTGGCGCGTCGCTCAACGAAGCGGAAAAGCATTTCAACAACTA
CGTGAACTCCGAAGCGATCGCAGGCAAAGATCCGGCGTTGGATACCCAGGCCGAAGCCAGCTTTAAGCAGATGTATGACG
TTTTGCAGCAGTCTATCCACTATCTTAAAGCCGATAATTACGCCGCCTATGGCAACCTTGACGCGCAAAAAGCGCAGGAT
GACATGGAGCAGGTATATAACCAGTGGCTCTCTCAAAATGCGCAATTAATAAAATTAGCCAGCGATCAGAACCAGAGCAG
TTTTACCCAGATGCAATGGACGCTGGGGATAATTCTACTTATCGTGCTCATCGTACTGGCGTTTATCTGGCTGGGGCTGC
AACGCGTTCTACTCCGCCCGCTGCAACGGATTATGGCGCACATTCAAACTATCGCCGACGGCGATCTTACCCATGAGATA
GAGGCCGAAGGACGCAGTGAAATGGGCCAACTGGCCGCCGGTCTCAAAACGATGCAGCAGTCGTTAATCCGTACCGTCAG
CGCGGTGCGCGATAACGCAGACTCTATCTATACTGGCGCAGGCGAAATTTCCGCCGGTAGCAGCGACCTCTCTTCCCGTA
CCGAACAGCAGGCCTCGGCGCTGGAGGAGACCGCCGCCAGCATGGAACAGTTAACCGCCACGGTACGGCAAAACACCGAT
AACGCACGACAGGCGACGGGTCTGGCGAAAACCGCATCAGAAACCGCGCGTAAAGGAGGACGCGTGGTGGATAACGTAGT
GAGCACCATGAACGATATCGCCGAAAGTTCGGAAAAAATCGTGGACATCACCAGCGTGATTGACGGTATCGCCTTCCAGA
CTAATATCCTGGCGCTGAACGCCGCGGTAGAAGCCGCCCGCGCCGGCGAACAGGGGCGAGGATTCGCGGTCGTCGCCGGA
GAGGTACGCACGTTGGCCAGCCGTAGCGCGCAGGCTGCCAAAGAGATCAAAGTACTGATTGAAAACTCCGTGTCGCGCAT
TGATACCGGCTCTACGCAGGTACGCGAAGCGGGAGAAACCATGAAAGAGATCGTCAACGCCGTGACCCGCGTGACCGATA
TTATGGGCGAAATCGCCTCTGCCTCCGATGAGCAAAGCAAAGGCATTGAGCAGGTGGCGCAGGCGGTATCGGAAATGGAC
AGCGTGACGCAGCAAAACGCCTCGCTGGTAGAGGAATCCGCAGCAGCGGCAGCGGCGCTGGAAGATCAGGCTAACGAACT
TCGTCAGGCGGTCGCCGCGTTCCGCATCCAGAAACAGCCTCGTCGGGAGGCGTCGCCAACGCCGTTAAGCAAAGGTTTAA
CGCCACAGCCCGCCGCAGAACAGGCGAACTGGGAAAGCTTCTAA

Upstream 100 bases:

>100_bases
ATCAAACCATTAATCAGAAATAGCGTGATTTGATGTAAGGTTAATTTTTATCCAACCGATATTGATCATACCGTCTACAA
AATAAGGAATGTTAGGCACT

Downstream 100 bases:

>100_bases
TCAGAATGTTATCTGCCGTGCGGTTAATGCGCTTTACGCAATAAATAGCGGTACGGCAGACCCTCCGTCTCTTGCGCCAG
CAAATCGTGTTCCATAAAGG

Product: methyl-accepting chemotaxis protein I

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDP
ASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDTQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
DMEQVYNQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTD
NARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAEQANWESF

Sequences:

>Translated_547_residues
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDP
ASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDTQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
DMEQVYNQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTD
NARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAEQANWESF
>Mature_547_residues
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDP
ASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDTQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
DMEQVYNQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTD
NARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAEQANWESF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=554, Percent_Identity=53.6101083032491, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1788195, Length=555, Percent_Identity=53.3333333333333, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI1787690, Length=460, Percent_Identity=49.1304347826087, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1788194, Length=445, Percent_Identity=50.1123595505618, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1789453, Length=329, Percent_Identity=41.9452887537994, Blast_Score=221, Evalue=9e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58976; Mature: 58976

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50885 HAMP ; PS00538 CHEMOTAXIS_TRANSDUC_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHH
ETRVTINRVAIRMLKNQRDPASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DTQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQDDMEQVYNQWLSQNAQLIKLA
CCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
SDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
LEETAASMEQLTATVRQNTDNARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAKEIKVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
QANWESF
CCCCCCC
>Mature Secondary Structure
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHH
ETRVTINRVAIRMLKNQRDPASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DTQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQDDMEQVYNQWLSQNAQLIKLA
CCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
SDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
LEETAASMEQLTATVRQNTDNARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAKEIKVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
QANWESF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]