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The map label for this gene is gst [H]

Identifier: 194734274

GI number: 194734274

Start: 1489656

End: 1490261

Strand: Reverse

Name: gst [H]

Synonym: SeSA_A1548

Alternate gene names: 194734274

Gene position: 1490261-1489656 (Counterclockwise)

Preceding gene: 194737597

Following gene: 194736925

Centisome position: 31.65

GC content: 50.83

Gene sequence:

>606_bases
ATGAAACTGTTCTACAAACCGGGTGCCTGCTCTCTTGCTTCCCATATTACCCTGCGCGAAATTGGCAAAGACTTTACGCT
TGATGGCGTCGATCTCGCAAAAAAACGCCTGGAAAATGGTGATGATTACCTGGCAGTCAACCCTAAAGGACAGGTTCCAG
CTCTGCTGCTGGATGACGGCACACTGTTGACTGAAGGCGTCGCCATTATGCAGTATCTCGCCGACAGCGTTCCCGACCGC
CAGCTTCTGGCGCCGGTAAGTAGTCTTGCTCGCTATCATACGCTGGAATGGCTCAACTATATTGCAACGGAACTGCATAA
AGGCTTTACCCCTCTGTTCCGCCCTGACACGCCAGAAACACTCAAACCCGCCGTTCGCGCCGGTCTGGAAAAGAAATTGC
AGTATGTGGATGAGTCGCTTTCAGACGACCAGTGGATTTGCGGCCAGCGTTTTACCATTGCAGACGCTTATCTGTTTACC
GTATTGCGTTGGGCCTATGGCGTAAAACTGAATATGGACGGGTTAACGCATATTGAAAGTTATATGCAGCGTGTCGCAAA
AAGACCGACCGTTGCGGCAGCGCTTAAAGCGGAAGGACTGAATTAA

Upstream 100 bases:

>100_bases
CCGGGAAACAACATTCAGGCCGCTAACTGTGCGTTAGCGGCTTTTTTTTTGCTCGTCCCCGCACTACCATACTTTAAACC
TCAGCAAAAAGGAGTTACCG

Downstream 100 bases:

>100_bases
TGTCATGTTGCCGGATAGCTCGCTGTACCGCCATCCGGCCTCTTTTTAACAGCAATAATTACAGCCGCGTTGCGCTGAAG
TAATGTTCAGGGTTAGCGAT

Product: glutathionine S-transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKLFYKPGACSLASHITLREIGKDFTLDGVDLAKKRLENGDDYLAVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDR
QLLAPVSSLARYHTLEWLNYIATELHKGFTPLFRPDTPETLKPAVRAGLEKKLQYVDESLSDDQWICGQRFTIADAYLFT
VLRWAYGVKLNMDGLTHIESYMQRVAKRPTVAAALKAEGLN

Sequences:

>Translated_201_residues
MKLFYKPGACSLASHITLREIGKDFTLDGVDLAKKRLENGDDYLAVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDR
QLLAPVSSLARYHTLEWLNYIATELHKGFTPLFRPDTPETLKPAVRAGLEKKLQYVDESLSDDQWICGQRFTIADAYLFT
VLRWAYGVKLNMDGLTHIESYMQRVAKRPTVAAALKAEGLN
>Mature_201_residues
MKLFYKPGACSLASHITLREIGKDFTLDGVDLAKKRLENGDDYLAVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDR
QLLAPVSSLARYHTLEWLNYIATELHKGFTPLFRPDTPETLKPAVRAGLEKKLQYVDESLSDDQWICGQRFTIADAYLFT
VLRWAYGVKLNMDGLTHIESYMQRVAKRPTVAAALKAEGLN

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=201, Percent_Identity=83.5820895522388, Blast_Score=333, Evalue=5e-93,
Organism=Escherichia coli, GI1787726, Length=205, Percent_Identity=27.8048780487805, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22443; Mature: 22443

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFYKPGACSLASHITLREIGKDFTLDGVDLAKKRLENGDDYLAVNPKGQVPALLLDDG
CCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEECCC
TLLTEGVAIMQYLADSVPDRQLLAPVSSLARYHTLEWLNYIATELHKGFTPLFRPDTPET
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
LKPAVRAGLEKKLQYVDESLSDDQWICGQRFTIADAYLFTVLRWAYGVKLNMDGLTHIES
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHCCEECCCHHHHHHH
YMQRVAKRPTVAAALKAEGLN
HHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure
MKLFYKPGACSLASHITLREIGKDFTLDGVDLAKKRLENGDDYLAVNPKGQVPALLLDDG
CCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEECCC
TLLTEGVAIMQYLADSVPDRQLLAPVSSLARYHTLEWLNYIATELHKGFTPLFRPDTPET
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
LKPAVRAGLEKKLQYVDESLSDDQWICGQRFTIADAYLFTVLRWAYGVKLNMDGLTHIES
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHCCEECCCHHHHHHH
YMQRVAKRPTVAAALKAEGLN
HHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]