Click here to switch to the map view.

The map label for this gene is ftsA [H]

Identifier: 194734257

GI number: 194734257

Start: 154252

End: 155514

Strand: Direct

Name: ftsA [H]

Synonym: SeSA_A0148

Alternate gene names: 194734257

Gene position: 154252-155514 (Clockwise)

Preceding gene: 194738119

Following gene: 194737199

Centisome position: 3.28

GC content: 53.6

Gene sequence:

>1263_bases
ATGATCAAGGCGACGGACAGAAAACTGGTAGTAGGACTGGAGATTGGCACCGCGAAGGTTGCCGCTTTAGTAGGGGAAGT
TCTGCCCGACGGTATGGTCAATATCATTGGCGTGGGCAGTTGCCCATCGCGGGGTATGGATAAAGGCGGGGTGAATGACC
TTGAGTCAGTGGTGAAATGCGTTCAGCGCGCCATTGACCAGGCGGAATTGATGGCCGATTGCCAGATCTCCTCGGTATAT
CTGGCGCTTTCCGGCAAACATATTAGCTGTCAGAATGAAATTGGTATGGTGCCCATTTCCGAAGAGGAAGTGACGCAGGA
AGATGTGGAAAACGTCGTGCATACTGCGAAGTCAGTGCGCGTGCGCGATGAACATCGCGTGCTGCATGTGATTCCTCAGG
AGTACGCCATTGACTACCAGGAAGGCATTAAAAATCCGGTCGGTCTTTCCGGCGTGCGTATGCAGGCGAAAGTACATTTG
ATTACCTGCCACAACGATATGGCAAAAAACATTGTCAAAGCTGTTGAACGTTGTGGTCTGAAAGTTGACCAACTGATATT
TGCCGGACTGGCGGCCAGTTATTCCGTGTTAACGGAAGATGAACGTGAACTGGGCGTCTGTGTCGTGGATATCGGCGGTG
GTACAATGGATATCGCCGTTTATACTGGCGGCGCGCTGCGTCATACCAAAGTGATCCCTTACGCGGGGAACGTGGTGACC
AGCGATATCGCTTATGCCTTTGGTACGCCGCCGAGCGATGCTGAAGCCATTAAAGTCCGCCACGGTTGCGCGTTGGGTTC
CATCGTCGGTAAAGACGAGAGCGTTGAAGTACCGAGCGTAGGCGGGCGTCCGCCGCGCAGCCTGCAACGTCAGACGCTGG
CGGAAGTGATTGAGCCGCGTTACACCGAGCTGCTCAATCTGGTCAACGAAGAGATATTGCAATTACAGGAACAGCTTCGC
CAACAAGGGGTAAAACATCACCTGGCGGCGGGGATTGTGTTAACCGGCGGAGCGGCGCAAATCGAAGGGCTTGCTGCTTG
CGCTCAGCGCGTGTTTCATACGCAGGTGCGTATCGGCGCGCCGCTGAATATCACCGGTCTGACGGATTATGCCCAGGAGC
CGTATTACTCAACGGCGGTGGGATTGCTTCACTACGGGAAAGAGTCCCACTTAAACGGTGAAGCAGAAGTGGAAAAACGT
GTTACGGCATCAGTTGGCTCGTGGATCAAGCGACTTAATAGCTGGCTGCGAAAAGAGTTTTAA

Upstream 100 bases:

>100_bases
ACGTTGATTTGCGTTATGACTCAGGTGCGGCAGTTGGCTGGGCGCCGCTCCCCCCTGAGGAATCTAATCAGCAACAGAAT
CAGGCACAGGCAGAACAACA

Downstream 100 bases:

>100_bases
TTTTTTATGAGGCCGCCAGATATTACGGCCTCAGGCGACAGGCACATGACGGAGAGAGATTATGTTTGAACCTATGGAAC
TAACCAACGACGCGGTGATT

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVY
LALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
ITCHNDMAKNIVKAVERCGLKVDQLIFAGLAASYSVLTEDERELGVCVVDIGGGTMDIAVYTGGALRHTKVIPYAGNVVT
SDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEQLR
QQGVKHHLAAGIVLTGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLNGEAEVEKR
VTASVGSWIKRLNSWLRKEF

Sequences:

>Translated_420_residues
MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVY
LALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
ITCHNDMAKNIVKAVERCGLKVDQLIFAGLAASYSVLTEDERELGVCVVDIGGGTMDIAVYTGGALRHTKVIPYAGNVVT
SDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEQLR
QQGVKHHLAAGIVLTGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLNGEAEVEKR
VTASVGSWIKRLNSWLRKEF
>Mature_420_residues
MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVY
LALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
ITCHNDMAKNIVKAVERCGLKVDQLIFAGLAASYSVLTEDERELGVCVVDIGGGTMDIAVYTGGALRHTKVIPYAGNVVT
SDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEQLR
QQGVKHHLAAGIVLTGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLNGEAEVEKR
VTASVGSWIKRLNSWLRKEF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=420, Percent_Identity=99.5238095238095, Blast_Score=853, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45315; Mature: 45315

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKC
CCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
VQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVR
HHHHHHHHHHHHCCCEEEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCE
VRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHLITCHNDMAKNIVKAVERCGL
ECCCCCEEEECCHHHCCCHHHHCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCC
KVDQLIFAGLAASYSVLTEDERELGVCVVDIGGGTMDIAVYTGGALRHTKVIPYAGNVVT
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEEECCCCCCCHH
SDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVEVPSVGGRPPRSLQRQTLAEVIEPR
HHHHHHCCCCCCCCHHEEECCCCEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
YTELLNLVNEEILQLQEQLRQQGVKHHLAAGIVLTGGAAQIEGLAACAQRVFHTQVRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHEEECC
PLNITGLTDYAQEPYYSTAVGLLHYGKESHLNGEAEVEKRVTASVGSWIKRLNSWLRKEF
CEEECCCCHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKC
CCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
VQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVR
HHHHHHHHHHHHCCCEEEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCE
VRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHLITCHNDMAKNIVKAVERCGL
ECCCCCEEEECCHHHCCCHHHHCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCC
KVDQLIFAGLAASYSVLTEDERELGVCVVDIGGGTMDIAVYTGGALRHTKVIPYAGNVVT
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEEECCCCCCCHH
SDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVEVPSVGGRPPRSLQRQTLAEVIEPR
HHHHHHCCCCCCCCHHEEECCCCEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
YTELLNLVNEEILQLQEQLRQQGVKHHLAAGIVLTGGAAQIEGLAACAQRVFHTQVRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHEEECC
PLNITGLTDYAQEPYYSTAVGLLHYGKESHLNGEAEVEKRVTASVGSWIKRLNSWLRKEF
CEEECCCCHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]