| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is sptP [H]
Identifier: 194734059
GI number: 194734059
Start: 2929276
End: 2930883
Strand: Reverse
Name: sptP [H]
Synonym: SeSA_A3031
Alternate gene names: 194734059
Gene position: 2930883-2929276 (Counterclockwise)
Preceding gene: 194738043
Following gene: 194736644
Centisome position: 62.24
GC content: 43.66
Gene sequence:
>1608_bases TTGAATAATTTAACGTTGTCTTCGTTTTCAAAAGTTGGTGTGTCGAATGATGCCCGACTTTATATTGCTAAGGAAAATAC TGATAAGGCATATGTTGCGCCTGAAAAATTTTCGTCAAAAGTATTAACCTGGCTTGGAAAAATGCCGTTATTTAAAAACA CTGAAGTGGTGCAAAAACATACGGAAAACATCAAAGGACAGGATCAGAAAATTTTACAAACATTTCTCCAGGCACTAACG GAAAAATATGGGGAAACAGCGGTCAATAACGCACTGTTAATGTCCCGTATAAATATGAACAAACCCCTTACCCAACGTTT AGCAGTGCAGATCACGGAGTGTGTAAAAGCTGCTGACGAAGGGTTTATAAACCTTATTAAGAGCAAGGATAATGTTGGTG TCATGAATGCCGCTTTAGTCATAAAAGGCGGCGATACAAAAGTGGCAGAAAAAAATAACGATGTTGGAGCAGAAAGTAAG CAACCTTTACTCGATATCGCGCTAAAGGGACTTAAAAGAACATTACCGCAACTGGAACAAATGGATGGAAATAGCCTGCG AGAAAACTTCCAGGAGATGGCTTCAGGTAACGGCCCGCTACGTTCATTAATGACGAATTTACAGAATTTAAATAAAATTC CAGAGGCTAAACAACTTAATGATTATGTTACAACGTTAAAAAATATTCAGATAGGAGCAGACAGGTTCTCACAATGGGGA ACCTGTGGGGGAGTGGTTGAGAGGTGGATTGATAAAGCCTCTACTCATGAATTAACCCAGGCTGTAAAAAAAATTCACGT TATTGCTAAAGAACTGAAAAACGTTACAGCTGAACTTGAGAAAATAGAAGCCGGCGCGCCAATGCCACAGACGATGAGCG GACCGACACTGGGCCTGGCACGGTTTGCGGTCAGCAGCATTCCAATTAATCAGCAAACCCAAGTGAAACTGAGCGATGGA ATGCCTGTGCCAGTGAATACGTTAACTTTTGACGGTAAGCCTGTGGCATTAGCCGGTTCGTACCCAAAAAATACGCCGGA TGCGCTGGAAGCGCATATGAAAATGCTTCTTGAAAAAGAATGCTCGTGCTTGGTGGTGTTAACGTCGGAAGATCAGATGC AGGCAAAACAATTACCACCCTATTTCAGAGGGAGCTACACTTTTGGCGAGGTGCATACCAACAGCCAAAAAGTGAGCTCA GCCAGTCAGGGAGGAGCGATAGACCAATACAATATGCACCTGTCCTGCGGGGAAAAGCAGTATACAATCCCGGTATTGCA TGTGAAAAATTGGCCAGATCACCAGCCGTTACCGTCTACTGATCAGTTAGAATACCTGGCAGATAGGGTGAAAAATAGTA ACCAAAATGGCGCGCCGGGGCGTAGTTCATCAGATAAGTATTTACCGATGATTCATTGTCTGGACGGAGTGGGGAGAACC GGAACGATGGCGGCGGCTCTTGTACTTAAGGATAATCCTCATAGTAATCTGGAGCAGGTACGTGCAGATTTCCGGGATTC ACGGAACAATAGAATGCTGGAAGACGCCTCACAGTTTGTACAACTAAAAGCAATGCAAGCCCAGTTGCTTATGACGACGG CAAGCTGA
Upstream 100 bases:
>100_bases AATACTTACCATATTATATCGCAGCTTGAGTCATTTGTGAATCAGCAGGAAGCGCTCAAAAACATACTGCAGGAATATGC TAAAGTATGAGGAGAGAAAA
Downstream 100 bases:
>100_bases TAAAAACATAGCTTACTTTTAGAACTATCTGAAAGTAAGCTATTTCTGTATAATTATTTGTTTACCGCGATAGAAAGTCT TTTGTTTTTCTCTTCTGCTG
Product: effector protein SptP
Products: NA
Alternate protein names: GTPase-activating protein; GAP; Tyrosine-protein phosphatase [H]
Number of amino acids: Translated: 535; Mature: 535
Protein sequence:
>535_residues MNNLTLSSFSKVGVSNDARLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIKGQDQKILQTFLQALT EKYGETAVNNALLMSRINMNKPLTQRLAVQITECVKAADEGFINLIKSKDNVGVMNAALVIKGGDTKVAEKNNDVGAESK QPLLDIALKGLKRTLPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQNLNKIPEAKQLNDYVTTLKNIQIGADRFSQWG TCGGVVERWIDKASTHELTQAVKKIHVIAKELKNVTAELEKIEAGAPMPQTMSGPTLGLARFAVSSIPINQQTQVKLSDG MPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPPYFRGSYTFGEVHTNSQKVSS ASQGGAIDQYNMHLSCGEKQYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKYLPMIHCLDGVGRT GTMAAALVLKDNPHSNLEQVRADFRDSRNNRMLEDASQFVQLKAMQAQLLMTTAS
Sequences:
>Translated_535_residues MNNLTLSSFSKVGVSNDARLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIKGQDQKILQTFLQALT EKYGETAVNNALLMSRINMNKPLTQRLAVQITECVKAADEGFINLIKSKDNVGVMNAALVIKGGDTKVAEKNNDVGAESK QPLLDIALKGLKRTLPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQNLNKIPEAKQLNDYVTTLKNIQIGADRFSQWG TCGGVVERWIDKASTHELTQAVKKIHVIAKELKNVTAELEKIEAGAPMPQTMSGPTLGLARFAVSSIPINQQTQVKLSDG MPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPPYFRGSYTFGEVHTNSQKVSS ASQGGAIDQYNMHLSCGEKQYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKYLPMIHCLDGVGRT GTMAAALVLKDNPHSNLEQVRADFRDSRNNRMLEDASQFVQLKAMQAQLLMTTAS >Mature_535_residues MNNLTLSSFSKVGVSNDARLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIKGQDQKILQTFLQALT EKYGETAVNNALLMSRINMNKPLTQRLAVQITECVKAADEGFINLIKSKDNVGVMNAALVIKGGDTKVAEKNNDVGAESK QPLLDIALKGLKRTLPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQNLNKIPEAKQLNDYVTTLKNIQIGADRFSQWG TCGGVVERWIDKASTHELTQAVKKIHVIAKELKNVTAELEKIEAGAPMPQTMSGPTLGLARFAVSSIPINQQTQVKLSDG MPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPPYFRGSYTFGEVHTNSQKVSS ASQGGAIDQYNMHLSCGEKQYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKYLPMIHCLDGVGRT GTMAAALVLKDNPHSNLEQVRADFRDSRNNRMLEDASQFVQLKAMQAQLLMTTAS
Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal
COG id: NA
COG function: NA
Gene ontology:
Cell location: Secreted. Host cytoplasm (By similarity). Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cytoplasm (By similarity) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 tyrosine-protein phosphatase domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000387 - InterPro: IPR011070 - InterPro: IPR015203 - InterPro: IPR016130 - InterPro: IPR003546 - InterPro: IPR000242 - InterPro: IPR014773 [H]
Pfam domain/function: PF09119 SicP-binding; PF00102 Y_phosphatase; PF03545 YopE [H]
EC number: =3.1.3.48 [H]
Molecular weight: Translated: 58917; Mature: 58917
Theoretical pI: Translated: 8.71; Mature: 8.71
Prosite motif: PS00383 TYR_PHOSPHATASE_1 ; PS50056 TYR_PHOSPHATASE_2 ; PS50055 TYR_PHOSPHATASE_PTP
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNNLTLSSFSKVGVSNDARLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKH CCCCCCCHHHHCCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHCCCCCCCHHHHHHH TENIKGQDQKILQTFLQALTEKYGETAVNNALLMSRINMNKPLTQRLAVQITECVKAADE HHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH GFINLIKSKDNVGVMNAALVIKGGDTKVAEKNNDVGAESKQPLLDIALKGLKRTLPQLEQ HHHHHHHCCCCCCEEEEEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH MDGNSLRENFQEMASGNGPLRSLMTNLQNLNKIPEAKQLNDYVTTLKNIQIGADRFSQWG CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEECHHHHHCCC TCGGVVERWIDKASTHELTQAVKKIHVIAKELKNVTAELEKIEAGAPMPQTMSGPTLGLA CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH RFAVSSIPINQQTQVKLSDGMPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKE HHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCC CSCLVVLTSEDQMQAKQLPPYFRGSYTFGEVHTNSQKVSSASQGGAIDQYNMHLSCGEKQ CCEEEEECCCCHHHHHHCCCCCCCCCEECEEECCHHHHHCCCCCCCCEEEEEEEECCCCE YTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKYLPMIHCLDGVGRT EEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCC GTMAAALVLKDNPHSNLEQVRADFRDSRNNRMLEDASQFVQLKAMQAQLLMTTAS CCEEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECC >Mature Secondary Structure MNNLTLSSFSKVGVSNDARLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKH CCCCCCCHHHHCCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHCCCCCCCHHHHHHH TENIKGQDQKILQTFLQALTEKYGETAVNNALLMSRINMNKPLTQRLAVQITECVKAADE HHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH GFINLIKSKDNVGVMNAALVIKGGDTKVAEKNNDVGAESKQPLLDIALKGLKRTLPQLEQ HHHHHHHCCCCCCEEEEEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH MDGNSLRENFQEMASGNGPLRSLMTNLQNLNKIPEAKQLNDYVTTLKNIQIGADRFSQWG CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEECHHHHHCCC TCGGVVERWIDKASTHELTQAVKKIHVIAKELKNVTAELEKIEAGAPMPQTMSGPTLGLA CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH RFAVSSIPINQQTQVKLSDGMPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKE HHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCC CSCLVVLTSEDQMQAKQLPPYFRGSYTFGEVHTNSQKVSSASQGGAIDQYNMHLSCGEKQ CCEEEEECCCCHHHHHHCCCCCCCCCEECEEECCHHHHHCCCCCCCCEEEEEEEECCCCE YTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKYLPMIHCLDGVGRT EEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCC GTMAAALVLKDNPHSNLEQVRADFRDSRNNRMLEDASQFVQLKAMQAQLLMTTAS CCEEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA