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The map label for this gene is mgtC

Identifier: 194734001

GI number: 194734001

Start: 3844990

End: 3845667

Strand: Reverse

Name: mgtC

Synonym: SeSA_A3971

Alternate gene names: 194734001

Gene position: 3845667-3844990 (Counterclockwise)

Preceding gene: 194736905

Following gene: 194737976

Centisome position: 81.67

GC content: 50.74

Gene sequence:

>678_bases
ATGTTTCCTTATATTTTGAATTTACTGGCCGCTATGCTGTTGGGCGCGCTGATTGGCGCGGAAAGACAATGGCGTCAACG
TATGGCGGGATTACGCACTAATGCGCTGGTGGCGACAGGCGCCGCCGTTTTTATTCTGAGCTCCATGACGACATCGCCAG
ACAGCCCCGGGAGAATTGCGGCGCAGATTGTCTCTGGTATTGGCTTTCTGGGGGCGGGCGTCATCATGCGCGAAGGGATG
AATGTGCGCGGGCTGAACACTGCGGCAACGCTATGGTGTTCGGCGGGCATCGGCGTGTTATGCGGCTTAGGGCAGTTCAA
AAATGCGCTGGCGGCGACGATCATTATTCTTTGTGCCAATATTTTACTGCGTGAAGCGGCGCAGCGTATAAATCAACTCC
CGGTATCCGCCGAGGGAGAAAAACGTTATATCCTGAAAGTAACCTGTAATAAAGAAGATGAGAGCGAGGTTCGTCAGTGG
TTACTGAATATCGTAAAAGAGGCCGCGATCTGTTTACAAGGGTTAGGTTCGGTCCCCGCTCAGGAACAGGGCTATAAAGA
AATCCGTGCCGAGCTCGTGGGTCATGCTGATTATCGTAAAACGCGAGAACTGATTATATCCAGAATAGGTGATAACGATA
ATATCACCGCAATTCACTGGAGCATTGATAGTCAATAA

Upstream 100 bases:

>100_bases
CGCCGTTAACACGACGCTAATTGCCTCAGGGCAGAGATTTGTCGTGTGCTAAATATAGCACGTACTTATTCTTCCAGAAA
AAATGGAGGAACGTATGTTA

Downstream 100 bases:

>100_bases
TAGTTTTTATTCAATTGCAACATTACGCCAGGCGTATAAGGAGGGAATGATGGATATTCCCGAGTCGATAAAATAAAACC
CACTCAAAATAGTGAGTAAG

Product: protein MgtC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGVIMREGM
NVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPVSAEGEKRYILKVTCNKEDESEVRQW
LLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ

Sequences:

>Translated_225_residues
MFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGVIMREGM
NVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPVSAEGEKRYILKVTCNKEDESEVRQW
LLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ
>Mature_225_residues
MFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGVIMREGM
NVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPVSAEGEKRYILKVTCNKEDESEVRQW
LLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family

Homologues:

Organism=Escherichia coli, GI1789924, Length=168, Percent_Identity=31.547619047619, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MGTC_SALCH (Q57I71)

Other databases:

- EMBL:   AE017220
- RefSeq:   YP_218672.1
- GeneID:   3336209
- GenomeReviews:   AE017220_GR
- KEGG:   sec:SC3685
- HOGENOM:   HBG708751
- OMA:   REHENAV
- ProtClustDB:   PRK15385
- BioCyc:   SENT321314:SCH_3685-MONOMER
- GO:   GO:0009405
- InterPro:   IPR003416
- PRINTS:   PR01837

Pfam domain/function: PF02308 MgtC

EC number: NA

Molecular weight: Translated: 24320; Mature: 24320

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x218adb68)-; HASH(0x22ad2bec)-; HASH(0x217b5e58)-; HASH(0x22845ab0)-;

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AQIVSGIGFLGAGVIMREGMNVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCAN
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHH
ILLREAAQRINQLPVSAEGEKRYILKVTCNKEDESEVRQWLLNIVKEAAICLQGLGSVPA
HHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
QEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCH
>Mature Secondary Structure
MFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AQIVSGIGFLGAGVIMREGMNVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCAN
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHH
ILLREAAQRINQLPVSAEGEKRYILKVTCNKEDESEVRQWLLNIVKEAAICLQGLGSVPA
HHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
QEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA