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The map label for this gene is rsmH

Identifier: 194335059

GI number: 194335059

Start: 2451394

End: 2452395

Strand: Reverse

Name: rsmH

Synonym: Paes_2271

Alternate gene names: 194335059

Gene position: 2452395-2451394 (Counterclockwise)

Preceding gene: 194335060

Following gene: 194335058

Centisome position: 97.59

GC content: 55.19

Gene sequence:

>1002_bases
ATGGAACATGATGGATACCACCTTCCGGTCATGGTCAGCGAAGTTACCGACTTGCTTGCCAGAAGACCGGGGATCTACAT
TGACGGCACCCTTGGCGGCGGCGGCCACGCCTTTTCGGTGATGAGTGCCCTTCGCCGGTCCGGTTTTGAAAACGATTCAT
TACTGATCGGCATCGATCAGGATTCCTTCGCCCTCGAAGAGGCTGCCGGGAGACTGCGGCCTTTTGCTTCAAGGGTCCGG
CTTGAACGGGGAAATTTCAGCGAGATGGCTGCCATTATCGAGCGCATACGTTTACGCGAGGGGTGCAGGCTGCCGGTTAT
GGGTATTCTGCTCGATCTTGGCGTTTCATCGTTTCAGATCGATACCCCTGACAGGGGGTTCAGTTATTTGCGTCAGGGGC
CGCTGGATATGAGAATGGACCCTGATGGAGGGTGGAGTGCTGCCGATATTGTCAATACTGCTGAAGAGTCGGAGCTTGCA
GGAATCATCTATCGATATGGAGAGGAGAAGAAGAGCCGGGCGATAGCCAGGGCGATCAAGGCCCGTGTCCGGGAGAAAGG
GGATTTCAGGGAGACTGCGGAGCTGGCGGCAGTTGTCCGTTCGGTTGTCGCCGGTCATGATCGCCAGATAAAATCTCTCT
CCCGTGTGTTCCAGGCGCTGCGTATCGCGGTTAACGACGAACTTGGTGTTCTTGAAAGCGCTCTTGAGGACGGGACAGCA
TGCCTTGCTCCGTCTGGACGAATGGGCGTTATGAGTTATCACTCGCTTGAAGACAGGATGGTGAAGAGGTTTTTCCGGGA
CAAGTCGGAGGACGACTGGGGACCGAAAGGGGTCGGGCTTCGCGAGCCCTTGCGGTCGGCCGGCTTCAAACTGGTGACAA
GGAAATCCGTCGTTGCTTCAGACGACGAGGTTCGCATAAACCCCCGGGCAAGAAGTGCAAGGTTGCGTGTGATTGAAAAA
AAAGAGCTGGAAGGAGAATCTCATGATCGAGTCTATCAATAA

Upstream 100 bases:

>100_bases
ATGTCAAGATGATCCTCTGGGCGCCGGAAAAATTATCGAAAGTTGTTCGTGACAATGCTTCCAGGTTTCAGGTCCTGGCC
GGCAGATATTTTTAGTACGT

Downstream 100 bases:

>100_bases
ATTGTTGCCTGTCGACCGCGTCGCTTCCGTGACAAAAGCGGCCGTTATGAAGGCGGGGCCTGCGGTGCAGCCTTCTTTTG
AGCGAATTAAAAAAAAACTT

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MEHDGYHLPVMVSEVTDLLARRPGIYIDGTLGGGGHAFSVMSALRRSGFENDSLLIGIDQDSFALEEAAGRLRPFASRVR
LERGNFSEMAAIIERIRLREGCRLPVMGILLDLGVSSFQIDTPDRGFSYLRQGPLDMRMDPDGGWSAADIVNTAEESELA
GIIYRYGEEKKSRAIARAIKARVREKGDFRETAELAAVVRSVVAGHDRQIKSLSRVFQALRIAVNDELGVLESALEDGTA
CLAPSGRMGVMSYHSLEDRMVKRFFRDKSEDDWGPKGVGLREPLRSAGFKLVTRKSVVASDDEVRINPRARSARLRVIEK
KELEGESHDRVYQ

Sequences:

>Translated_333_residues
MEHDGYHLPVMVSEVTDLLARRPGIYIDGTLGGGGHAFSVMSALRRSGFENDSLLIGIDQDSFALEEAAGRLRPFASRVR
LERGNFSEMAAIIERIRLREGCRLPVMGILLDLGVSSFQIDTPDRGFSYLRQGPLDMRMDPDGGWSAADIVNTAEESELA
GIIYRYGEEKKSRAIARAIKARVREKGDFRETAELAAVVRSVVAGHDRQIKSLSRVFQALRIAVNDELGVLESALEDGTA
CLAPSGRMGVMSYHSLEDRMVKRFFRDKSEDDWGPKGVGLREPLRSAGFKLVTRKSVVASDDEVRINPRARSARLRVIEK
KELEGESHDRVYQ
>Mature_333_residues
MEHDGYHLPVMVSEVTDLLARRPGIYIDGTLGGGGHAFSVMSALRRSGFENDSLLIGIDQDSFALEEAAGRLRPFASRVR
LERGNFSEMAAIIERIRLREGCRLPVMGILLDLGVSSFQIDTPDRGFSYLRQGPLDMRMDPDGGWSAADIVNTAEESELA
GIIYRYGEEKKSRAIARAIKARVREKGDFRETAELAAVVRSVVAGHDRQIKSLSRVFQALRIAVNDELGVLESALEDGTA
CLAPSGRMGVMSYHSLEDRMVKRFFRDKSEDDWGPKGVGLREPLRSAGFKLVTRKSVVASDDEVRINPRARSARLRVIEK
KELEGESHDRVYQ

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=347, Percent_Identity=36.3112391930836, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI165377202, Length=200, Percent_Identity=39.5, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1786270, Length=324, Percent_Identity=41.9753086419753, Blast_Score=204, Evalue=5e-54,
Organism=Drosophila melanogaster, GI62472493, Length=338, Percent_Identity=32.2485207100592, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571637, Length=338, Percent_Identity=32.2485207100592, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_PROA2 (B4S6R7)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016919.1
- ProteinModelPortal:   B4S6R7
- SMR:   B4S6R7
- GeneID:   6459546
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_2271
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- ProtClustDB:   CLSK637125
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 37038; Mature: 37038

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: BINDING 59-59 BINDING 86-86 BINDING 112-112 BINDING 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHDGYHLPVMVSEVTDLLARRPGIYIDGTLGGGGHAFSVMSALRRSGFENDSLLIGIDQ
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
DSFALEEAAGRLRPFASRVRLERGNFSEMAAIIERIRLREGCRLPVMGILLDLGVSSFQI
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEE
DTPDRGFSYLRQGPLDMRMDPDGGWSAADIVNTAEESELAGIIYRYGEEKKSRAIARAIK
CCCCHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ARVREKGDFRETAELAAVVRSVVAGHDRQIKSLSRVFQALRIAVNDELGVLESALEDGTA
HHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCE
CLAPSGRMGVMSYHSLEDRMVKRFFRDKSEDDWGPKGVGLREPLRSAGFKLVTRKSVVAS
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEEHHHHHCC
DDEVRINPRARSARLRVIEKKELEGESHDRVYQ
CCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEHDGYHLPVMVSEVTDLLARRPGIYIDGTLGGGGHAFSVMSALRRSGFENDSLLIGIDQ
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
DSFALEEAAGRLRPFASRVRLERGNFSEMAAIIERIRLREGCRLPVMGILLDLGVSSFQI
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEE
DTPDRGFSYLRQGPLDMRMDPDGGWSAADIVNTAEESELAGIIYRYGEEKKSRAIARAIK
CCCCHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ARVREKGDFRETAELAAVVRSVVAGHDRQIKSLSRVFQALRIAVNDELGVLESALEDGTA
HHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCE
CLAPSGRMGVMSYHSLEDRMVKRFFRDKSEDDWGPKGVGLREPLRSAGFKLVTRKSVVAS
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEEHHHHHCC
DDEVRINPRARSARLRVIEKKELEGESHDRVYQ
CCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA