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The map label for this gene is spoVD [H]

Identifier: 194335057

GI number: 194335057

Start: 2448876

End: 2450918

Strand: Reverse

Name: spoVD [H]

Synonym: Paes_2269

Alternate gene names: 194335057

Gene position: 2450918-2448876 (Counterclockwise)

Preceding gene: 194335058

Following gene: 194335056

Centisome position: 97.53

GC content: 52.96

Gene sequence:

>2043_bases
ATGAAGATACATAACATCGGACATCGCCAGTCACCTTCAGCCAGGAGCGGTGGTAAGGAGTTTGGCATGCGCCTGGGGAT
CCTCTCTCTTGGGTATGCGCTTTTTTTTGTCGCTATTGTGCTCCGTCTGCTCAATATACAGGTGATCGATGTCAAGAAAT
ATAAAAACAAGGCGTCACGGCAGTACCAGCGCGATGTGGTCGAGCAGGCAAAGCGAGGGGTCGTCATGGACCGTAACGGC
CATCTTCTGGCTCAAAGTGTTCAGACCATATCGTTTTATGCTGATCCCTGGCTTGTAGCAAATACGGAAGTCAAGGTCGG
CAGGAAAAAAGTTGCCGTCGATAAGACGCCTGACGTGGCCAGGCTTTTTGCTCAGCGATTCGGCAAAAGCCGTGAGCACT
ATATGCGTATCCTTCGTAACGGGCAGAAACAGAAGCGCCGCTTTATCTGGCTGGAGCGATCCGTTCCTGTTGAACATGCA
CGCGAGCTGATGGAGACTGCTATGACCGGGATTGATTTCAAAAAAGAGCAGTACCGGTATTATCTGAATCTTGCGCCTCA
GGTTGTCGGGCTGGTCAATACCGACAACAAGGGAATCAGCGGTCTCGAAATCAAATATGATCATGAGCTCAGGGGGCGTG
ACGGGATGAAGATTTTCCAGCGATCGGCAACCGGCACCAGGTTTCTTGCCGCCGACGCCGATCAGGTCAGTGCAAAGGAG
GGACTTAGCCTGCAGCTTACTCTTGATGCCGATATGCAGTCGATTGTCGAGTCTGAAATAGCAAGTGCCGCGAAAGAGTT
CAATGCTTCGGCAGCGGTCGGTATTGTCATGGATGTGAAAACAGGCGCTATTCTGGCTATGGCCAACTATCCGACCTTTG
ATATGAACAATCGCAAGGGGTTTCGGGAATCGGATGCGAGGAACCGCGCAATTATCGACGCGTTCGACCCCGGGTCGACA
TTCAAGATCGTGATGGCTTCGGCAGCAAGGGAGGTACTGCATAGAGCTGCTGAGGATAGTGTCGATGCCCATAACGGAGT
TTTCCATATCTATAACCGTACGATCAGGGATCATGAGAAATTCGAACGGTGTACTTTTCGTGACGCTATGGTGCATTCCA
GCAATATCGTCGCCGCAAAAACCGCTATGGAGCTCGGGGAGAAGACCTTTTACGACTATGTCAGGAGATTCGGTTTCGGA
GAGCAGACCGGTATTGGGCTTGTTGGCGAGTCGGAGGGGATTGTACGGCCTCTGAAGCAGTGGAATAAAACCACCCTGCC
GTGGATGGGCTATGGATATTCCGTGACCACGACGCCGCTGCAGATTCTTCAGGCCTATGCTGCGATCGCCAATGACGGGG
TTCTGATGAAGCCATATATCGTCGAGCGCCTGGTCGATGCTGACGGCAATGCCGTGAGTGAATTCAAACCGGAGAAGGTG
CGCAATGTTGTTTCGGCTGAAACAGCCCGCTATATCAGAAAAGAGTATCTGCAGCCTATTGTCGAAGAGGGGACCGGTGT
TGCGGCAGCCGTGAAAGGGGTCACTGTCGGGGGTAAGACAGGAACGGCTCAGAAGCTGAGTAACGGCAACTACAATAGAG
GTCCCCGAAGCTATATCGCGTCGTTTGTCGGCTTTTTTCCTGTAGACGAACCGCGGATTGCTGCCATTATCGTGGTTGAC
GAGCCTCAGTCCGCATACTATGCAAGTACCGTCGCTGCGCCGTCGTTTGCACGCATCTGTACCCGTATGATTGCCTGCTC
AGAGGATCTCAAGGCCGATCTCGGCATGACTGCTCCTGAAGCGGTGGTTCTTGCTGCCAGCAAGAGTGTTGCCGTTCCTC
TGCTGACCGGTCTGAAAGCCAGGGATGCGGAAAAGCTCTTGATATGGAATGGCCTCGATATCAGTATGAACGGAGACCGG
GAGGGAGTTGTGGTTGAACAGGATATTGCGGCAGGCTCGATGGTGGAGCCCGGAAGCCGGGTACGGGTCGGACTTTCGGC
TCAGGAGAATCAGGACCCCGGCAGTAAATCATCGGTAATGTAG

Upstream 100 bases:

>100_bases
TATCCACAGGATTTCAAGTCAGGCGGAAAAGCACGGGCTGCGTGAAAGTGCTGTTCCTGCCGTTGAGATTTTCTATTGAC
AGGCGAAAGGAATGTAAGCC

Downstream 100 bases:

>100_bases
TGGTGAACAAGGTGTTGTTATGATGACGTTGGAAGATCTTATCGGATTGCTTGATCCGCTCGAATATCTTGCCGGCAGAA
CCCCGCTGAAAGAGGTTCAT

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MKIHNIGHRQSPSARSGGKEFGMRLGILSLGYALFFVAIVLRLLNIQVIDVKKYKNKASRQYQRDVVEQAKRGVVMDRNG
HLLAQSVQTISFYADPWLVANTEVKVGRKKVAVDKTPDVARLFAQRFGKSREHYMRILRNGQKQKRRFIWLERSVPVEHA
RELMETAMTGIDFKKEQYRYYLNLAPQVVGLVNTDNKGISGLEIKYDHELRGRDGMKIFQRSATGTRFLAADADQVSAKE
GLSLQLTLDADMQSIVESEIASAAKEFNASAAVGIVMDVKTGAILAMANYPTFDMNNRKGFRESDARNRAIIDAFDPGST
FKIVMASAAREVLHRAAEDSVDAHNGVFHIYNRTIRDHEKFERCTFRDAMVHSSNIVAAKTAMELGEKTFYDYVRRFGFG
EQTGIGLVGESEGIVRPLKQWNKTTLPWMGYGYSVTTTPLQILQAYAAIANDGVLMKPYIVERLVDADGNAVSEFKPEKV
RNVVSAETARYIRKEYLQPIVEEGTGVAAAVKGVTVGGKTGTAQKLSNGNYNRGPRSYIASFVGFFPVDEPRIAAIIVVD
EPQSAYYASTVAAPSFARICTRMIACSEDLKADLGMTAPEAVVLAASKSVAVPLLTGLKARDAEKLLIWNGLDISMNGDR
EGVVVEQDIAAGSMVEPGSRVRVGLSAQENQDPGSKSSVM

Sequences:

>Translated_680_residues
MKIHNIGHRQSPSARSGGKEFGMRLGILSLGYALFFVAIVLRLLNIQVIDVKKYKNKASRQYQRDVVEQAKRGVVMDRNG
HLLAQSVQTISFYADPWLVANTEVKVGRKKVAVDKTPDVARLFAQRFGKSREHYMRILRNGQKQKRRFIWLERSVPVEHA
RELMETAMTGIDFKKEQYRYYLNLAPQVVGLVNTDNKGISGLEIKYDHELRGRDGMKIFQRSATGTRFLAADADQVSAKE
GLSLQLTLDADMQSIVESEIASAAKEFNASAAVGIVMDVKTGAILAMANYPTFDMNNRKGFRESDARNRAIIDAFDPGST
FKIVMASAAREVLHRAAEDSVDAHNGVFHIYNRTIRDHEKFERCTFRDAMVHSSNIVAAKTAMELGEKTFYDYVRRFGFG
EQTGIGLVGESEGIVRPLKQWNKTTLPWMGYGYSVTTTPLQILQAYAAIANDGVLMKPYIVERLVDADGNAVSEFKPEKV
RNVVSAETARYIRKEYLQPIVEEGTGVAAAVKGVTVGGKTGTAQKLSNGNYNRGPRSYIASFVGFFPVDEPRIAAIIVVD
EPQSAYYASTVAAPSFARICTRMIACSEDLKADLGMTAPEAVVLAASKSVAVPLLTGLKARDAEKLLIWNGLDISMNGDR
EGVVVEQDIAAGSMVEPGSRVRVGLSAQENQDPGSKSSVM
>Mature_680_residues
MKIHNIGHRQSPSARSGGKEFGMRLGILSLGYALFFVAIVLRLLNIQVIDVKKYKNKASRQYQRDVVEQAKRGVVMDRNG
HLLAQSVQTISFYADPWLVANTEVKVGRKKVAVDKTPDVARLFAQRFGKSREHYMRILRNGQKQKRRFIWLERSVPVEHA
RELMETAMTGIDFKKEQYRYYLNLAPQVVGLVNTDNKGISGLEIKYDHELRGRDGMKIFQRSATGTRFLAADADQVSAKE
GLSLQLTLDADMQSIVESEIASAAKEFNASAAVGIVMDVKTGAILAMANYPTFDMNNRKGFRESDARNRAIIDAFDPGST
FKIVMASAAREVLHRAAEDSVDAHNGVFHIYNRTIRDHEKFERCTFRDAMVHSSNIVAAKTAMELGEKTFYDYVRRFGFG
EQTGIGLVGESEGIVRPLKQWNKTTLPWMGYGYSVTTTPLQILQAYAAIANDGVLMKPYIVERLVDADGNAVSEFKPEKV
RNVVSAETARYIRKEYLQPIVEEGTGVAAAVKGVTVGGKTGTAQKLSNGNYNRGPRSYIASFVGFFPVDEPRIAAIIVVD
EPQSAYYASTVAAPSFARICTRMIACSEDLKADLGMTAPEAVVLAASKSVAVPLLTGLKARDAEKLLIWNGLDISMNGDR
EGVVVEQDIAAGSMVEPGSRVRVGLSAQENQDPGSKSSVM

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=559, Percent_Identity=30.4114490161002, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1786854, Length=615, Percent_Identity=23.2520325203252, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 75023; Mature: 75023

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHNIGHRQSPSARSGGKEFGMRLGILSLGYALFFVAIVLRLLNIQVIDVKKYKNKASR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHH
QYQRDVVEQAKRGVVMDRNGHLLAQSVQTISFYADPWLVANTEVKVGRKKVAVDKTPDVA
HHHHHHHHHHHCCEEECCCCCCHHHHHHHEEEECCCEEEECCEEECCCEEEECCCCCHHH
RLFAQRFGKSREHYMRILRNGQKQKRRFIWLERSVPVEHARELMETAMTGIDFKKEQYRY
HHHHHHHCCCHHHHHHHHHCCHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHE
YLNLAPQVVGLVNTDNKGISGLEIKYDHELRGRDGMKIFQRSATGTRFLAADADQVSAKE
EEEECCEEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCEEEECCCHHHHHHC
GLSLQLTLDADMQSIVESEIASAAKEFNASAAVGIVMDVKTGAILAMANYPTFDMNNRKG
CCEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCC
FRESDARNRAIIDAFDPGSTFKIVMASAAREVLHRAAEDSVDAHNGVFHIYNRTIRDHEK
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHH
FERCTFRDAMVHSSNIVAAKTAMELGEKTFYDYVRRFGFGEQTGIGLVGESEGIVRPLKQ
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHH
WNKTTLPWMGYGYSVTTTPLQILQAYAAIANDGVLMKPYIVERLVDADGNAVSEFKPEKV
CCCCCCCEECCCCEEEHHHHHHHHHHHHHHCCCEEECHHHHHHHHCCCCCCHHHCCHHHH
RNVVSAETARYIRKEYLQPIVEEGTGVAAAVKGVTVGGKTGTAQKLSNGNYNRGPRSYIA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHCCCCCCCCHHHHHH
SFVGFFPVDEPRIAAIIVVDEPQSAYYASTVAAPSFARICTRMIACSEDLKADLGMTAPE
HHHHCCCCCCCCEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHCHHHHHHCCCCCCC
AVVLAASKSVAVPLLTGLKARDAEKLLIWNGLDISMNGDREGVVVEQDIAAGSMVEPGSR
EEEEECCCCCCHHHHHCCCCCCCCEEEEEECEEEEECCCCCCEEEECCCCCCCCCCCCCC
VRVGLSAQENQDPGSKSSVM
EEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIHNIGHRQSPSARSGGKEFGMRLGILSLGYALFFVAIVLRLLNIQVIDVKKYKNKASR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHH
QYQRDVVEQAKRGVVMDRNGHLLAQSVQTISFYADPWLVANTEVKVGRKKVAVDKTPDVA
HHHHHHHHHHHCCEEECCCCCCHHHHHHHEEEECCCEEEECCEEECCCEEEECCCCCHHH
RLFAQRFGKSREHYMRILRNGQKQKRRFIWLERSVPVEHARELMETAMTGIDFKKEQYRY
HHHHHHHCCCHHHHHHHHHCCHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHE
YLNLAPQVVGLVNTDNKGISGLEIKYDHELRGRDGMKIFQRSATGTRFLAADADQVSAKE
EEEECCEEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCEEEECCCHHHHHHC
GLSLQLTLDADMQSIVESEIASAAKEFNASAAVGIVMDVKTGAILAMANYPTFDMNNRKG
CCEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCC
FRESDARNRAIIDAFDPGSTFKIVMASAAREVLHRAAEDSVDAHNGVFHIYNRTIRDHEK
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHH
FERCTFRDAMVHSSNIVAAKTAMELGEKTFYDYVRRFGFGEQTGIGLVGESEGIVRPLKQ
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHH
WNKTTLPWMGYGYSVTTTPLQILQAYAAIANDGVLMKPYIVERLVDADGNAVSEFKPEKV
CCCCCCCEECCCCEEEHHHHHHHHHHHHHHCCCEEECHHHHHHHHCCCCCCHHHCCHHHH
RNVVSAETARYIRKEYLQPIVEEGTGVAAAVKGVTVGGKTGTAQKLSNGNYNRGPRSYIA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHCCCCCCCCHHHHHH
SFVGFFPVDEPRIAAIIVVDEPQSAYYASTVAAPSFARICTRMIACSEDLKADLGMTAPE
HHHHCCCCCCCCEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHCHHHHHHCCCCCCC
AVVLAASKSVAVPLLTGLKARDAEKLLIWNGLDISMNGDREGVVVEQDIAAGSMVEPGSR
EEEEECCCCCCHHHHHCCCCCCCCEEEEEECEEEEECCCCCCEEEECCCCCCCCCCCCCC
VRVGLSAQENQDPGSKSSVM
EEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]