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The map label for this gene is ftsZ [H]

Identifier: 194335046

GI number: 194335046

Start: 2435040

End: 2436326

Strand: Reverse

Name: ftsZ [H]

Synonym: Paes_2258

Alternate gene names: 194335046

Gene position: 2436326-2435040 (Counterclockwise)

Preceding gene: 194335047

Following gene: 194335045

Centisome position: 96.95

GC content: 51.28

Gene sequence:

>1287_bases
ATGGCATTTGAACTGGATCCGGGTTTGTTTGAGCACGAGCAGGATATTGGCGTTTCTATCAAGGTTGTCGGGGTCGGTGG
TTGTGGCGGTAACGCTGTCAACAATATGATTGACAGGAAGATTTCCGGAGTGGATTTTATCGCGTTTAACACCGACCGTC
AGGCACTTCTGAATTCAAAAGCGCCTGTGCGTATTCAGATCGGTAAAAAGGCAACCAATGGCCTTGGTGCAGGAGCTGAT
CCTGCAAAGGGCCGTCAGGCGGCCGAGGATGATCGCGAAATCATTGCCGGCCAGCTTCGGGGTGCTGATCTTGTCTTTAT
TACGGCAGGAATGGGAAAAGGGACAGGAACCGGTGCTGCTCCGGTGATAGCCTCTATCGCCCGCAACATGGGGATTCTTT
CTGTCGGGGTCGTGACCAGACCCTTCAATTTTGAGGGCAGGATCAAAGCAGGTATTGCCGATAGCGGTATTGCTGAACTG
GGGAAGTATATAGATACCCTTATCGTTATCGAGAACGAGAGGATTCTCAGTATTGCCGAGGAAGGCATCAGCGCAACCGA
CGCATTTAACATGGCTAACGATGTGCTTTACCGCGCAGCTAAAGGTATTGCCGATATTATAACACGCCATGGCCATGTGA
ATGTGGATTTTGCCGATGTCCGCAGTATTATGTCCGGTGCAGGGGATGCTGTTATGGGGTCTGCGGCCGCTTCCGGAGAC
CGCAGGGCGCTGAAGGCCGCCTCGGATGCCATTACCAGTCCTTTGCTCGAAGGGGTTTCTTTAAAAGGCTCGAAAGGGGT
TCTGGTCAATATGACCGGCGATGTGACCATGCGTGACATGTCAGACGCAATGAGTTATATCGAAGAGCAGGTTGGAAAGG
ATGCTAAAATTATCAACGGTTATGTTGAGGACCGCGATGCATCCGGCGAGATTCGTGTAACGGTCATTGTGACCGGTTTC
AATCGTCAGCACCATGATGATGAGGGCGATGCAGATCATCCCTATGTCGTTGATATGCCTGGGAGCAAAACGTTACCGCA
GCACTCCTTTGTCCGCCAGACCGCATCTCCGGGGTATCACGGTCAGAAACCCGACGATCTTCGTGTTCCTGCCTATATTC
GCAGAAAAATTTCAATCCATGATCCTCTGGACCTTGGCAGTGGAAAGTCGCATAAGCCGCAGAACGACGAATCTGATGAG
ATTACCATGCCCTCTTCCCGTTCTTCCGATGACAGGATTCGAAAAGGATCCACTGATACGCCGGCTTATTTACGCCGTCG
TCATTAA

Upstream 100 bases:

>100_bases
TCAGTCCGGTAAAAAGATTGTCGATCGTTTGAAAGACTGGTGGGAAAGATTATAGGGTGATTGAGCTCTGGAGGCGAGTA
TAAAAGGGAGAATATGAGCT

Downstream 100 bases:

>100_bases
TATACGCTCATTGTGGGGGGGCTGCCTGCATATCTTTTGCATGCATGTAACCTTGTAGAGGGTATAAGGCTGTTGTTCTT
TAATCGGGGTATGTTATTTT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MAFELDPGLFEHEQDIGVSIKVVGVGGCGGNAVNNMIDRKISGVDFIAFNTDRQALLNSKAPVRIQIGKKATNGLGAGAD
PAKGRQAAEDDREIIAGQLRGADLVFITAGMGKGTGTGAAPVIASIARNMGILSVGVVTRPFNFEGRIKAGIADSGIAEL
GKYIDTLIVIENERILSIAEEGISATDAFNMANDVLYRAAKGIADIITRHGHVNVDFADVRSIMSGAGDAVMGSAAASGD
RRALKAASDAITSPLLEGVSLKGSKGVLVNMTGDVTMRDMSDAMSYIEEQVGKDAKIINGYVEDRDASGEIRVTVIVTGF
NRQHHDDEGDADHPYVVDMPGSKTLPQHSFVRQTASPGYHGQKPDDLRVPAYIRRKISIHDPLDLGSGKSHKPQNDESDE
ITMPSSRSSDDRIRKGSTDTPAYLRRRH

Sequences:

>Translated_428_residues
MAFELDPGLFEHEQDIGVSIKVVGVGGCGGNAVNNMIDRKISGVDFIAFNTDRQALLNSKAPVRIQIGKKATNGLGAGAD
PAKGRQAAEDDREIIAGQLRGADLVFITAGMGKGTGTGAAPVIASIARNMGILSVGVVTRPFNFEGRIKAGIADSGIAEL
GKYIDTLIVIENERILSIAEEGISATDAFNMANDVLYRAAKGIADIITRHGHVNVDFADVRSIMSGAGDAVMGSAAASGD
RRALKAASDAITSPLLEGVSLKGSKGVLVNMTGDVTMRDMSDAMSYIEEQVGKDAKIINGYVEDRDASGEIRVTVIVTGF
NRQHHDDEGDADHPYVVDMPGSKTLPQHSFVRQTASPGYHGQKPDDLRVPAYIRRKISIHDPLDLGSGKSHKPQNDESDE
ITMPSSRSSDDRIRKGSTDTPAYLRRRH
>Mature_427_residues
AFELDPGLFEHEQDIGVSIKVVGVGGCGGNAVNNMIDRKISGVDFIAFNTDRQALLNSKAPVRIQIGKKATNGLGAGADP
AKGRQAAEDDREIIAGQLRGADLVFITAGMGKGTGTGAAPVIASIARNMGILSVGVVTRPFNFEGRIKAGIADSGIAELG
KYIDTLIVIENERILSIAEEGISATDAFNMANDVLYRAAKGIADIITRHGHVNVDFADVRSIMSGAGDAVMGSAAASGDR
RALKAASDAITSPLLEGVSLKGSKGVLVNMTGDVTMRDMSDAMSYIEEQVGKDAKIINGYVEDRDASGEIRVTVIVTGFN
RQHHDDEGDADHPYVVDMPGSKTLPQHSFVRQTASPGYHGQKPDDLRVPAYIRRKISIHDPLDLGSGKSHKPQNDESDEI
TMPSSRSSDDRIRKGSTDTPAYLRRRH

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=359, Percent_Identity=44.8467966573816, Blast_Score=259, Evalue=2e-70,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 45519; Mature: 45388

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFELDPGLFEHEQDIGVSIKVVGVGGCGGNAVNNMIDRKISGVDFIAFNTDRQALLNSK
CCEECCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHCCC
APVRIQIGKKATNGLGAGADPAKGRQAAEDDREIIAGQLRGADLVFITAGMGKGTGTGAA
CCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHH
PVIASIARNMGILSVGVVTRPFNFEGRIKAGIADSGIAELGKYIDTLIVIENERILSIAE
HHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHEEEEEECCCCEEHHHH
EGISATDAFNMANDVLYRAAKGIADIITRHGHVNVDFADVRSIMSGAGDAVMGSAAASGD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCHHCCCCCCCCC
RRALKAASDAITSPLLEGVSLKGSKGVLVNMTGDVTMRDMSDAMSYIEEQVGKDAKIING
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHHCCCCEEEEC
YVEDRDASGEIRVTVIVTGFNRQHHDDEGDADHPYVVDMPGSKTLPQHSFVRQTASPGYH
CCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCC
GQKPDDLRVPAYIRRKISIHDPLDLGSGKSHKPQNDESDEITMPSSRSSDDRIRKGSTDT
CCCCCCCCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHCCCCCC
PAYLRRRH
HHHHHCCC
>Mature Secondary Structure 
AFELDPGLFEHEQDIGVSIKVVGVGGCGGNAVNNMIDRKISGVDFIAFNTDRQALLNSK
CEECCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHCCC
APVRIQIGKKATNGLGAGADPAKGRQAAEDDREIIAGQLRGADLVFITAGMGKGTGTGAA
CCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHH
PVIASIARNMGILSVGVVTRPFNFEGRIKAGIADSGIAELGKYIDTLIVIENERILSIAE
HHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHEEEEEECCCCEEHHHH
EGISATDAFNMANDVLYRAAKGIADIITRHGHVNVDFADVRSIMSGAGDAVMGSAAASGD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCHHCCCCCCCCC
RRALKAASDAITSPLLEGVSLKGSKGVLVNMTGDVTMRDMSDAMSYIEEQVGKDAKIING
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHHCCCCEEEEC
YVEDRDASGEIRVTVIVTGFNRQHHDDEGDADHPYVVDMPGSKTLPQHSFVRQTASPGYH
CCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCC
GQKPDDLRVPAYIRRKISIHDPLDLGSGKSHKPQNDESDEITMPSSRSSDDRIRKGSTDT
CCCCCCCCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHCCCCCC
PAYLRRRH
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9403685; 1490605 [H]