Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 194335038

GI number: 194335038

Start: 2427438

End: 2428403

Strand: Reverse

Name: galE [H]

Synonym: Paes_2250

Alternate gene names: 194335038

Gene position: 2428403-2427438 (Counterclockwise)

Preceding gene: 194335040

Following gene: 194335037

Centisome position: 96.64

GC content: 52.07

Gene sequence:

>966_bases
ATGAAGATTCTGGTGATCGGCGGTGCAGGCTATATCGGTAGTCATGTCGCCCGGGCGTTTCTCGACAGCGGTTATAGTGT
CACGGTTTTCGATAATCTTGCTACCGGGGCAAGAGAGAACCTTTTTGAAGAGGCTCAATTTATTCATGGCGATATCATGC
AGCCGGATCATCTGCGCAAGGCCATGGCTCATGGATTTGACGCGTGTGTTCATCTCGCGGCGCTCAAAGCCGCCGGCCAG
TCGATGACGGATCCCGGATCCTATGCTACGGCTAATATCTGCGGAACGGTCAACATTTTGAATGCCCTCGTCGAAGCAGG
GATTCAAACCCTTATTTTTTCATCTTCAGCAGCCGTTTTTGGCAGTCCGTCTTTTCTGCCTATCGATGAGGATCATCCGA
AGAATCCTGAAAATTTCTACGGTTTTACCAAACTTGAGATAGAGCGTTTGCTTGCATGGTATGATCGCCTCAAGGGTCTG
AAATATGGCGCGATACGCTACTTCAACGCAGCTGGCTACGATGTGGCCGGGCGGATTACCGGCAGGGAACAGAATCCGGA
AAATCTGCTCCCTGTCGTGATGGAGGTCGCAGCAGGAATCCGGCCGCGGTTGTCAATTTTTGGTGATGACTACCCAACAA
GGGATGGTTCCTGTATCCGTGATTACGTTCATGTCAACGATCTGGCCAGAGCGCATGTTTTGGCATTTGAGTATATCCTG
AAGCAGAAGAGGAGCCTGGAGTTGAACCTGGGCAGTGAGCGGGGGGTGACGGTTCTTGAGATGATCAAAAAGGCTCGTGA
AATCACCGGTCAGCCTATTGCTGCCGATATCGCGCCCCGCCGTCCCGGCGACCCTGCTGAACTGGTGGCGTCATCGGCAA
AGGCCCTTCGTCTCATAGGCTGGAAGGCCGAACACAGTGATGTCGATACCTTGATCAGTTCAACGTGGAGTGTGTATAAG
AAGTGA

Upstream 100 bases:

>100_bases
TAAAATAGCTAAAACGGCTGGTTGCGCCCATTAAAATCGCCGAAAGTGTTATCTTCAGCAGTCACGCAACAGAGGCAGTA
TTCAACCCCACGACACAATT

Downstream 100 bases:

>100_bases
GACAGGAGACAGGAGACAGGAGACAGGAGACAGGAGACAGGAGACAGGAGACAGGAGACAGGAGACAGGAGACAGGAGAC
AGGAGACAGGAGACAGGAGA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKILVIGGAGYIGSHVARAFLDSGYSVTVFDNLATGARENLFEEAQFIHGDIMQPDHLRKAMAHGFDACVHLAALKAAGQ
SMTDPGSYATANICGTVNILNALVEAGIQTLIFSSSAAVFGSPSFLPIDEDHPKNPENFYGFTKLEIERLLAWYDRLKGL
KYGAIRYFNAAGYDVAGRITGREQNPENLLPVVMEVAAGIRPRLSIFGDDYPTRDGSCIRDYVHVNDLARAHVLAFEYIL
KQKRSLELNLGSERGVTVLEMIKKAREITGQPIAADIAPRRPGDPAELVASSAKALRLIGWKAEHSDVDTLISSTWSVYK
K

Sequences:

>Translated_321_residues
MKILVIGGAGYIGSHVARAFLDSGYSVTVFDNLATGARENLFEEAQFIHGDIMQPDHLRKAMAHGFDACVHLAALKAAGQ
SMTDPGSYATANICGTVNILNALVEAGIQTLIFSSSAAVFGSPSFLPIDEDHPKNPENFYGFTKLEIERLLAWYDRLKGL
KYGAIRYFNAAGYDVAGRITGREQNPENLLPVVMEVAAGIRPRLSIFGDDYPTRDGSCIRDYVHVNDLARAHVLAFEYIL
KQKRSLELNLGSERGVTVLEMIKKAREITGQPIAADIAPRRPGDPAELVASSAKALRLIGWKAEHSDVDTLISSTWSVYK
K
>Mature_321_residues
MKILVIGGAGYIGSHVARAFLDSGYSVTVFDNLATGARENLFEEAQFIHGDIMQPDHLRKAMAHGFDACVHLAALKAAGQ
SMTDPGSYATANICGTVNILNALVEAGIQTLIFSSSAAVFGSPSFLPIDEDHPKNPENFYGFTKLEIERLLAWYDRLKGL
KYGAIRYFNAAGYDVAGRITGREQNPENLLPVVMEVAAGIRPRLSIFGDDYPTRDGSCIRDYVHVNDLARAHVLAFEYIL
KQKRSLELNLGSERGVTVLEMIKKAREITGQPIAADIAPRRPGDPAELVASSAKALRLIGWKAEHSDVDTLISSTWSVYK
K

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=339, Percent_Identity=35.9882005899705, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI56118217, Length=339, Percent_Identity=35.9882005899705, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI189083684, Length=339, Percent_Identity=35.9882005899705, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI42516563, Length=314, Percent_Identity=25.4777070063694, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI193211614, Length=248, Percent_Identity=28.6290322580645, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI8393516, Length=248, Percent_Identity=28.6290322580645, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1786974, Length=327, Percent_Identity=35.474006116208, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1788353, Length=337, Percent_Identity=27.5964391691395, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=34.7701149425287, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=34.5714285714286, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17539532, Length=331, Percent_Identity=22.6586102719033, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=321, Percent_Identity=37.0716510903427, Blast_Score=192, Evalue=5e-50,
Organism=Drosophila melanogaster, GI19923002, Length=336, Percent_Identity=37.797619047619, Blast_Score=211, Evalue=6e-55,
Organism=Drosophila melanogaster, GI21356223, Length=316, Percent_Identity=23.4177215189873, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35083; Mature: 35083

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVIGGAGYIGSHVARAFLDSGYSVTVFDNLATGARENLFEEAQFIHGDIMQPDHLRK
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHCCHHHHHHHHHHHHHCCCCCHHHHHH
AMAHGFDACVHLAALKAAGQSMTDPGSYATANICGTVNILNALVEAGIQTLIFSSSAAVF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GSPSFLPIDEDHPKNPENFYGFTKLEIERLLAWYDRLKGLKYGAIRYFNAAGYDVAGRIT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEC
GREQNPENLLPVVMEVAAGIRPRLSIFGDDYPTRDGSCIRDYVHVNDLARAHVLAFEYIL
CCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KQKRSLELNLGSERGVTVLEMIKKAREITGQPIAADIAPRRPGDPAELVASSAKALRLIG
HHHHCEEEECCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCC
WKAEHSDVDTLISSTWSVYKK
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKILVIGGAGYIGSHVARAFLDSGYSVTVFDNLATGARENLFEEAQFIHGDIMQPDHLRK
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHCCHHHHHHHHHHHHHCCCCCHHHHHH
AMAHGFDACVHLAALKAAGQSMTDPGSYATANICGTVNILNALVEAGIQTLIFSSSAAVF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GSPSFLPIDEDHPKNPENFYGFTKLEIERLLAWYDRLKGLKYGAIRYFNAAGYDVAGRIT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEC
GREQNPENLLPVVMEVAAGIRPRLSIFGDDYPTRDGSCIRDYVHVNDLARAHVLAFEYIL
CCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KQKRSLELNLGSERGVTVLEMIKKAREITGQPIAADIAPRRPGDPAELVASSAKALRLIG
HHHHCEEEECCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCC
WKAEHSDVDTLISSTWSVYKK
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]