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The map label for this gene is tal

Identifier: 194335019

GI number: 194335019

Start: 2409436

End: 2410107

Strand: Reverse

Name: tal

Synonym: Paes_2230

Alternate gene names: 194335019

Gene position: 2410107-2409436 (Counterclockwise)

Preceding gene: 194335020

Following gene: 194335016

Centisome position: 95.91

GC content: 53.42

Gene sequence:

>672_bases
ATGAAATTTTTCATTGATACCGCGAATCTTGACGAGATCAAAGCTGCAGCAGAACTGGGGCTGCTTGACGGGGTGACGAC
CAATCCATCCCTCATTGCAAAAATCGTTGCCGATCCAGCCAACTTCACCTATGAGGACTTCAAGAAGCATATCGCAGCTA
TCTGCGAGATTGTCGATGGTCCGATCAGTGCTGAAGTGACGACGCTTGAGGCAGAGGAGATGATCAGGGAGGGCGAGGAC
CTGGCGTCGATCCATGAGAACGTGGTGGTGAAGTGCCCTGTCACCCTTGAGGGGCTGAAAGCTATCCGTCACTTTTCGTC
CGAGGGGATCAGGACCAATGCGACCCTTGTCTTTTCACCTTCACAGGCGCTGCTTGCCGCAAAGGCAGGAGCGACGTACG
TCAGTCCCTTCATCGGAAGGCTGGACGATATCAGTACTGACGGAATGGCACTGGTCGAGCAGATCGTCGCTATCTACGAT
AACTATGGCTATCATACCGAGGTGATCGTTGCAAGCGTTCGTCATCCGCAGCATGTGGTCGAGGCTGCACTTGCCGGCGC
CGATATTGCTACGATTCCTTTCGGCGTTATCAAGCAGCTTGTGCGCCATCCACTGACCGATGCCGGCTTGACGAAGTTTA
TGGAAGACGCTTCGGTGATGAAGAAAAGCTGA

Upstream 100 bases:

>100_bases
GTTGTTTTCAATAAGCCGTCTTCAGTAGCCCGGTCATTACTGGATTATTTGTGAAGCGCGCATAGGCGAGAATCTGATAA
TAGAGAAAAAAGGAGCTTAC

Downstream 100 bases:

>100_bases
GGCACTCTCCGGCGCTTATCCTTCGAAGCCGAAGAGGTGACGTTCAAGATCGACGGTTCCGTCGTCAAGAAACGCCACCC
CTTCGGCTTCAAGCATGTCT

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKFFIDTANLDEIKAAAELGLLDGVTTNPSLIAKIVADPANFTYEDFKKHIAAICEIVDGPISAEVTTLEAEEMIREGED
LASIHENVVVKCPVTLEGLKAIRHFSSEGIRTNATLVFSPSQALLAAKAGATYVSPFIGRLDDISTDGMALVEQIVAIYD
NYGYHTEVIVASVRHPQHVVEAALAGADIATIPFGVIKQLVRHPLTDAGLTKFMEDASVMKKS

Sequences:

>Translated_223_residues
MKFFIDTANLDEIKAAAELGLLDGVTTNPSLIAKIVADPANFTYEDFKKHIAAICEIVDGPISAEVTTLEAEEMIREGED
LASIHENVVVKCPVTLEGLKAIRHFSSEGIRTNATLVFSPSQALLAAKAGATYVSPFIGRLDDISTDGMALVEQIVAIYD
NYGYHTEVIVASVRHPQHVVEAALAGADIATIPFGVIKQLVRHPLTDAGLTKFMEDASVMKKS
>Mature_223_residues
MKFFIDTANLDEIKAAAELGLLDGVTTNPSLIAKIVADPANFTYEDFKKHIAAICEIVDGPISAEVTTLEAEEMIREGED
LASIHENVVVKCPVTLEGLKAIRHFSSEGIRTNATLVFSPSQALLAAKAGATYVSPFIGRLDDISTDGMALVEQIVAIYD
NYGYHTEVIVASVRHPQHVVEAALAGADIATIPFGVIKQLVRHPLTDAGLTKFMEDASVMKKS

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=175, Percent_Identity=29.7142857142857, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI87081788, Length=216, Percent_Identity=33.7962962962963, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790382, Length=216, Percent_Identity=34.2592592592593, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1786189, Length=170, Percent_Identity=32.3529411764706, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788807, Length=211, Percent_Identity=29.3838862559242, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25153750, Length=129, Percent_Identity=34.1085271317829, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321480, Length=170, Percent_Identity=34.7058823529412, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45549185, Length=171, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_PROA2 (B4S6D0)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016879.1
- ProteinModelPortal:   B4S6D0
- SMR:   B4S6D0
- GeneID:   6459674
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_2230
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- ProtClustDB:   PRK01362
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23981; Mature: 23981

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 91-91

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFIDTANLDEIKAAAELGLLDGVTTNPSLIAKIVADPANFTYEDFKKHIAAICEIVDG
CEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
PISAEVTTLEAEEMIREGEDLASIHENVVVKCPVTLEGLKAIRHFSSEGIRTNATLVFSP
CCCCEEEEHHHHHHHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCEECEEEEECC
SQALLAAKAGATYVSPFIGRLDDISTDGMALVEQIVAIYDNYGYHTEVIVASVRHPQHVV
CHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHEECCCCHHHHH
EAALAGADIATIPFGVIKQLVRHPLTDAGLTKFMEDASVMKKS
HHHHCCCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFFIDTANLDEIKAAAELGLLDGVTTNPSLIAKIVADPANFTYEDFKKHIAAICEIVDG
CEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
PISAEVTTLEAEEMIREGEDLASIHENVVVKCPVTLEGLKAIRHFSSEGIRTNATLVFSP
CCCCEEEEHHHHHHHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCEECEEEEECC
SQALLAAKAGATYVSPFIGRLDDISTDGMALVEQIVAIYDNYGYHTEVIVASVRHPQHVV
CHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHEECCCCHHHHH
EAALAGADIATIPFGVIKQLVRHPLTDAGLTKFMEDASVMKKS
HHHHCCCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA