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The map label for this gene is feoB1 [H]

Identifier: 194335002

GI number: 194335002

Start: 2393239

End: 2395380

Strand: Reverse

Name: feoB1 [H]

Synonym: Paes_2213

Alternate gene names: 194335002

Gene position: 2395380-2393239 (Counterclockwise)

Preceding gene: 194335003

Following gene: 194335000

Centisome position: 95.32

GC content: 52.38

Gene sequence:

>2142_bases
ATGAATGAGCTGAAGGATATTACCGTCGCGCTTGCAGGTAACCCCAACTGCGGCAAATCATCGCTTTTCAACGCTTTGAC
AGGTTTACATCAGAAGGTTGGTAATTTTTCGGGCGTTACGATCGAGAGGCATGAGGGGTACGTTGACTACAATGGATACC
GTATTCGTTTTGTCGATCTTCCGGGAACCTACTCCCTGACGGCGTATTCTCCCGAAGAGCTGGTTACCAGGCATTATCTT
ACGATGGATCGCCCTGACATCGTCGTCAACGTGCTTGAAGGGCCGAACCTTGAGCGTAATCTGCTTCTGACTACCCAGCT
GATGGAAATGGAGGTGGAGCTGCTTGTCGCGCTCAACATGTTCGATGAAGTACAGGAACAGGGTATCGAAATCCGTGATA
AGCAGCTCCAGACGCTGCTCGGCTGCCATATCGTTCCGACTTCGGCAAAGAAGATGGAGGGGCTTGAGGCACTTCTCGAC
CATGTCGTTCGGGTTTACGAGGGTGATATTGAGATCCGCAAGAATAAACTGGCTTTTCGTCCGGAGCTTGAGCGGGCTAT
CGAAGAGATTGCAGGGGTCCTTGACCTAGAGCCTGATTTTGGCGGCAGTAATACTCGCTGGCTTGCCATCAAACTGCTTG
AGAACGATAAAGAGATCTACAGCCGGGTCAACCGTTATCCTGTCTGGGTTAAAATCGAGCTGCTTTTGCAGCAGGCTCTC
CAGGAGACGGAAAAGATGTATGCGTCCGATCCTGAAGTGCTCATTACCGAAGATCGTCATGCCTTTATCCGTGGAGCCAT
GAAGGAGTGCGTGCGGCTGCCGGAGGTGCGTAAGGTGTCTCTGACTGACTATATCGACCGGATTGTGCTGAACCGGGTAC
TCGGTCTGCCGATTTTTTTCTTTGTGGTCTGGCTGATCTTTCATATGACCTTTACGCTCGGGACGCCTCTCATGGAGGGG
CTGGACATGCTTTTCGGGGCGTTTGCTTCGGCCATCGAACCTTTCTTGCAGAACGAGACCGTTCGCTCGATTGTTGTTGA
CGGTATTATTGCCGGGGTCGGCGGCGTACTGATTTTTCTGCCCAACATTATTCTTCTTTTTATCGGGCTCTCATTTCTTG
AGGCATCAGGCTATATGGCCAGAGCGGCGTTCGTTGTCGACAAGGTGATGCATCGTTTCGGGCTTCACGGCAAGTCATTC
ATTCCGATGATTACCGGTTTCGGGTGTTCCATTCCCGCCATCATGGCGACACGCACCCTGAAAAGTCCCTCCGACCGTCT
GGCGACTATTCTCATCATTCCCTTTATGAGCTGCGGGGCTAAGCTGCCGGTGTATGTTCTCCTTGCCGGGGCGTTTTTTC
CTCCTGCAGCAGCGGCTAATGTGATGTTCGGGATCTATATGCTTGGTGTGGTTATCGGGCTTCTGACGGCACTGCTTCTG
CGTTCAGTCGTTCTTGAGAAGGAGTCTGAGCCTTTTGTGATGGAGTTGCCGCCCTATCGCTGGCCGACCCTTTCATCGGT
TTTTTTTCAGGCCCGGATCAAGGCGATGATGTATGTGAAAAAAGCCGGAACGGTCATTCTTTTTGCTGTCCTGGTTATCT
GGGCGGTGAGCAACTACCCCCGTAGTGCCGAACTTGACAAGGGGCTCGTTGCTGAGATCGAAAGGATTGAGCAGAGCTCT
CTCGATGGTGAAGAGATCGCCGTGGCTGTGACTGCAGCGCAAAACCGTGTCAGTGCGGCCCAGCTTGAATACTCTATCGC
CGGTCGTGCGGGCAGGTTTATCGAGCCAGTGATACGGCCGCTTGGTTTTGATTGGCGGATCGGTGTTGCGCTGGTGACGG
GTCTTGCTGCCAAGGAGATCGTTGTCTCGACCATGGGCACGATCTATTCTCTGGGAGAGGTCGACGAGGATTCCACAGAG
CTGAAAACCATACTCAGGAACGATTCTTCTTTTGATCAGGCGATTGCGTTGAGCCTGATGGTGTTCGTGCTGCTCTACAT
CCCGTGTGTGGCTGCTATCGGTGTCATGCAGAAAGAGATCGGACGCTGGAAACCGGTTTTGTTCTACTCCGTCTATGCGA
TGACGGTGGCATGGGTCGCCTCATTTATTACCTATAATGCAGCGCGCTTTCTTATGAACTGA

Upstream 100 bases:

>100_bases
AATCAGAAGCGGCAGGAGTTGTGGTTCAGAAAACCGGTCATACGGGAGATGCCAAACCATTGGGGCGAAAGAGACGGCGG
TGGGGACTTGGAGGTGGGCA

Downstream 100 bases:

>100_bases
CCCCGGTTTTCTGCTCCTCCATCAAGGGGATGAGACCTTTTTCTTCGGCAAATACCATGATCTCGTCGACCGTGAGCTGC
ATGTTCACAGGTGAACCGTC

Product: ferrous iron transport protein B

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MNELKDITVALAGNPNCGKSSLFNALTGLHQKVGNFSGVTIERHEGYVDYNGYRIRFVDLPGTYSLTAYSPEELVTRHYL
TMDRPDIVVNVLEGPNLERNLLLTTQLMEMEVELLVALNMFDEVQEQGIEIRDKQLQTLLGCHIVPTSAKKMEGLEALLD
HVVRVYEGDIEIRKNKLAFRPELERAIEEIAGVLDLEPDFGGSNTRWLAIKLLENDKEIYSRVNRYPVWVKIELLLQQAL
QETEKMYASDPEVLITEDRHAFIRGAMKECVRLPEVRKVSLTDYIDRIVLNRVLGLPIFFFVVWLIFHMTFTLGTPLMEG
LDMLFGAFASAIEPFLQNETVRSIVVDGIIAGVGGVLIFLPNIILLFIGLSFLEASGYMARAAFVVDKVMHRFGLHGKSF
IPMITGFGCSIPAIMATRTLKSPSDRLATILIIPFMSCGAKLPVYVLLAGAFFPPAAAANVMFGIYMLGVVIGLLTALLL
RSVVLEKESEPFVMELPPYRWPTLSSVFFQARIKAMMYVKKAGTVILFAVLVIWAVSNYPRSAELDKGLVAEIERIEQSS
LDGEEIAVAVTAAQNRVSAAQLEYSIAGRAGRFIEPVIRPLGFDWRIGVALVTGLAAKEIVVSTMGTIYSLGEVDEDSTE
LKTILRNDSSFDQAIALSLMVFVLLYIPCVAAIGVMQKEIGRWKPVLFYSVYAMTVAWVASFITYNAARFLMN

Sequences:

>Translated_713_residues
MNELKDITVALAGNPNCGKSSLFNALTGLHQKVGNFSGVTIERHEGYVDYNGYRIRFVDLPGTYSLTAYSPEELVTRHYL
TMDRPDIVVNVLEGPNLERNLLLTTQLMEMEVELLVALNMFDEVQEQGIEIRDKQLQTLLGCHIVPTSAKKMEGLEALLD
HVVRVYEGDIEIRKNKLAFRPELERAIEEIAGVLDLEPDFGGSNTRWLAIKLLENDKEIYSRVNRYPVWVKIELLLQQAL
QETEKMYASDPEVLITEDRHAFIRGAMKECVRLPEVRKVSLTDYIDRIVLNRVLGLPIFFFVVWLIFHMTFTLGTPLMEG
LDMLFGAFASAIEPFLQNETVRSIVVDGIIAGVGGVLIFLPNIILLFIGLSFLEASGYMARAAFVVDKVMHRFGLHGKSF
IPMITGFGCSIPAIMATRTLKSPSDRLATILIIPFMSCGAKLPVYVLLAGAFFPPAAAANVMFGIYMLGVVIGLLTALLL
RSVVLEKESEPFVMELPPYRWPTLSSVFFQARIKAMMYVKKAGTVILFAVLVIWAVSNYPRSAELDKGLVAEIERIEQSS
LDGEEIAVAVTAAQNRVSAAQLEYSIAGRAGRFIEPVIRPLGFDWRIGVALVTGLAAKEIVVSTMGTIYSLGEVDEDSTE
LKTILRNDSSFDQAIALSLMVFVLLYIPCVAAIGVMQKEIGRWKPVLFYSVYAMTVAWVASFITYNAARFLMN
>Mature_713_residues
MNELKDITVALAGNPNCGKSSLFNALTGLHQKVGNFSGVTIERHEGYVDYNGYRIRFVDLPGTYSLTAYSPEELVTRHYL
TMDRPDIVVNVLEGPNLERNLLLTTQLMEMEVELLVALNMFDEVQEQGIEIRDKQLQTLLGCHIVPTSAKKMEGLEALLD
HVVRVYEGDIEIRKNKLAFRPELERAIEEIAGVLDLEPDFGGSNTRWLAIKLLENDKEIYSRVNRYPVWVKIELLLQQAL
QETEKMYASDPEVLITEDRHAFIRGAMKECVRLPEVRKVSLTDYIDRIVLNRVLGLPIFFFVVWLIFHMTFTLGTPLMEG
LDMLFGAFASAIEPFLQNETVRSIVVDGIIAGVGGVLIFLPNIILLFIGLSFLEASGYMARAAFVVDKVMHRFGLHGKSF
IPMITGFGCSIPAIMATRTLKSPSDRLATILIIPFMSCGAKLPVYVLLAGAFFPPAAAANVMFGIYMLGVVIGLLTALLL
RSVVLEKESEPFVMELPPYRWPTLSSVFFQARIKAMMYVKKAGTVILFAVLVIWAVSNYPRSAELDKGLVAEIERIEQSS
LDGEEIAVAVTAAQNRVSAAQLEYSIAGRAGRFIEPVIRPLGFDWRIGVALVTGLAAKEIVVSTMGTIYSLGEVDEDSTE
LKTILRNDSSFDQAIALSLMVFVLLYIPCVAAIGVMQKEIGRWKPVLFYSVYAMTVAWVASFITYNAARFLMN

Specific function: Fe(2+) uptake system, probably driven by GTP [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=765, Percent_Identity=34.2483660130719, Blast_Score=371, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR003373
- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF04023 FeoA; PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 79417; Mature: 79417

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELKDITVALAGNPNCGKSSLFNALTGLHQKVGNFSGVTIERHEGYVDYNGYRIRFVDL
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCEEEEEEEC
PGTYSLTAYSPEELVTRHYLTMDRPDIVVNVLEGPNLERNLLLTTQLMEMEVELLVALNM
CCCEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHH
FDEVQEQGIEIRDKQLQTLLGCHIVPTSAKKMEGLEALLDHVVRVYEGDIEIRKNKLAFR
HHHHHHCCCCHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
PELERAIEEIAGVLDLEPDFGGSNTRWLAIKLLENDKEIYSRVNRYPVWVKIELLLQQAL
HHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCCHHHHHHHHCCCEEEEHHHHHHHHH
QETEKMYASDPEVLITEDRHAFIRGAMKECVRLPEVRKVSLTDYIDRIVLNRVLGLPIFF
HHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHH
FVVWLIFHMTFTLGTPLMEGLDMLFGAFASAIEPFLQNETVRSIVVDGIIAGVGGVLIFL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
PNIILLFIGLSFLEASGYMARAAFVVDKVMHRFGLHGKSFIPMITGFGCSIPAIMATRTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHC
KSPSDRLATILIIPFMSCGAKLPVYVLLAGAFFPPAAAANVMFGIYMLGVVIGLLTALLL
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSVVLEKESEPFVMELPPYRWPTLSSVFFQARIKAMMYVKKAGTVILFAVLVIWAVSNYP
HHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
RSAELDKGLVAEIERIEQSSLDGEEIAVAVTAAQNRVSAAQLEYSIAGRAGRFIEPVIRP
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCHHHHHHHHH
LGFDWRIGVALVTGLAAKEIVVSTMGTIYSLGEVDEDSTELKTILRNDSSFDQAIALSLM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
VFVLLYIPCVAAIGVMQKEIGRWKPVLFYSVYAMTVAWVASFITYNAARFLMN
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNELKDITVALAGNPNCGKSSLFNALTGLHQKVGNFSGVTIERHEGYVDYNGYRIRFVDL
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCEEEEEEEC
PGTYSLTAYSPEELVTRHYLTMDRPDIVVNVLEGPNLERNLLLTTQLMEMEVELLVALNM
CCCEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHH
FDEVQEQGIEIRDKQLQTLLGCHIVPTSAKKMEGLEALLDHVVRVYEGDIEIRKNKLAFR
HHHHHHCCCCHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
PELERAIEEIAGVLDLEPDFGGSNTRWLAIKLLENDKEIYSRVNRYPVWVKIELLLQQAL
HHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCCHHHHHHHHCCCEEEEHHHHHHHHH
QETEKMYASDPEVLITEDRHAFIRGAMKECVRLPEVRKVSLTDYIDRIVLNRVLGLPIFF
HHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHH
FVVWLIFHMTFTLGTPLMEGLDMLFGAFASAIEPFLQNETVRSIVVDGIIAGVGGVLIFL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
PNIILLFIGLSFLEASGYMARAAFVVDKVMHRFGLHGKSFIPMITGFGCSIPAIMATRTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHC
KSPSDRLATILIIPFMSCGAKLPVYVLLAGAFFPPAAAANVMFGIYMLGVVIGLLTALLL
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSVVLEKESEPFVMELPPYRWPTLSSVFFQARIKAMMYVKKAGTVILFAVLVIWAVSNYP
HHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
RSAELDKGLVAEIERIEQSSLDGEEIAVAVTAAQNRVSAAQLEYSIAGRAGRFIEPVIRP
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCHHHHHHHHH
LGFDWRIGVALVTGLAAKEIVVSTMGTIYSLGEVDEDSTELKTILRNDSSFDQAIALSLM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
VFVLLYIPCVAAIGVMQKEIGRWKPVLFYSVYAMTVAWVASFITYNAARFLMN
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]