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The map label for this gene is umuD [H]

Identifier: 194334990

GI number: 194334990

Start: 2374368

End: 2374820

Strand: Reverse

Name: umuD [H]

Synonym: Paes_2201

Alternate gene names: 194334990

Gene position: 2374820-2374368 (Counterclockwise)

Preceding gene: 194334991

Following gene: 194334989

Centisome position: 94.5

GC content: 50.55

Gene sequence:

>453_bases
ATGAAGCTTACGAGAATACATACAGCGCCTTCGCTGGATTTCTATGCATCGGATCTGACGATGGTGCTTGAACTTCCTGT
GGCCGGAACAGGGGTTGCCGCAGGGTTTCCATCTCCTGCGGAAGATGACGAGGAGTTGTCGCTCGATCTGAATAAGGCCC
TGATAAAGCATCCTGCCGCAACCTTCTATGCCAGGGTGAAAGGTTCTTCTATGAGGGATGCCGGTATTGTCGATGGTGAT
CTTCTGATCGTCGACAAGTCGCTTGAGGCCAAAGACGGCGATATCGCGGTATGCTTTCTCGATGGCGAGTTTACTGTCAA
GAGGATTGCCCTGCGGCAGGACGCTCTGTTCCTTATGCCGGCAAATGACGAATTTCAGCCTATCCGCATTACTGAAGAGA
GCGATTTTCTTGTTTGGGGTATCGTGACCTTTATTGTGCATAAACCGAGATAG

Upstream 100 bases:

>100_bases
GTTTTCACACGCGGAGCGTTCTTCCAGCGAGATGCTTTGTTCAAGGAGGTTGCTGCAACCGGGATTTCAGGCGTGCAGGT
CGCCGATTTTAAAAAAAAAT

Downstream 100 bases:

>100_bases
TCGGGAGAGGTATACGCCATGTTCGCTCTGGTTGACTGCAATAATTTTTACGCTTCGTGCGAGCGGGTGTTCAATCCGGC
GCTTGTCGGGCGGCCGGTCG

Product: peptidase S24 and S26 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKLTRIHTAPSLDFYASDLTMVLELPVAGTGVAAGFPSPAEDDEELSLDLNKALIKHPAATFYARVKGSSMRDAGIVDGD
LLIVDKSLEAKDGDIAVCFLDGEFTVKRIALRQDALFLMPANDEFQPIRITEESDFLVWGIVTFIVHKPR

Sequences:

>Translated_150_residues
MKLTRIHTAPSLDFYASDLTMVLELPVAGTGVAAGFPSPAEDDEELSLDLNKALIKHPAATFYARVKGSSMRDAGIVDGD
LLIVDKSLEAKDGDIAVCFLDGEFTVKRIALRQDALFLMPANDEFQPIRITEESDFLVWGIVTFIVHKPR
>Mature_150_residues
MKLTRIHTAPSLDFYASDLTMVLELPVAGTGVAAGFPSPAEDDEELSLDLNKALIKHPAATFYARVKGSSMRDAGIVDGD
LLIVDKSLEAKDGDIAVCFLDGEFTVKRIALRQDALFLMPANDEFQPIRITEESDFLVWGIVTFIVHKPR

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=134, Percent_Identity=44.7761194029851, Blast_Score=118, Evalue=1e-28,
Organism=Escherichia coli, GI1790476, Length=125, Percent_Identity=37.6, Blast_Score=80, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 16465; Mature: 16465

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTRIHTAPSLDFYASDLTMVLELPVAGTGVAAGFPSPAEDDEELSLDLNKALIKHPAA
CCEEEEECCCCCCEECCCEEEEEEECCCCCCEECCCCCCCCCCCEEEEEHHHHHHHCCCC
TFYARVKGSSMRDAGIVDGDLLIVDKSLEAKDGDIAVCFLDGEFTVKRIALRQDALFLMP
EEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEEECCEEEEEE
ANDEFQPIRITEESDFLVWGIVTFIVHKPR
CCCCCCEEEEECCCCEEHEEEEEEEEECCC
>Mature Secondary Structure
MKLTRIHTAPSLDFYASDLTMVLELPVAGTGVAAGFPSPAEDDEELSLDLNKALIKHPAA
CCEEEEECCCCCCEECCCEEEEEEECCCCCCEECCCCCCCCCCCEEEEEHHHHHHHCCCC
TFYARVKGSSMRDAGIVDGDLLIVDKSLEAKDGDIAVCFLDGEFTVKRIALRQDALFLMP
EEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEEECCEEEEEE
ANDEFQPIRITEESDFLVWGIVTFIVHKPR
CCCCCCEEEEECCCCEEHEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]