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The map label for this gene is nqrD [H]

Identifier: 194334926

GI number: 194334926

Start: 2310939

End: 2311568

Strand: Reverse

Name: nqrD [H]

Synonym: Paes_2135

Alternate gene names: 194334926

Gene position: 2311568-2310939 (Counterclockwise)

Preceding gene: 194334927

Following gene: 194334925

Centisome position: 91.99

GC content: 50.63

Gene sequence:

>630_bases
ATGGTTGACAAGAAGACACTGAAAACGCTCACCGAGCCCGTAGGTATGAGCAATCCCATCACAAAGCAGGTGCTCGGGAT
CTGTTCGGCTCTGGCCGTAACCGTCAAGATGGACACCGCTCTGGTGATGTCTGCTGCGCTGATTTTTGTTCTGGTCGGTT
CGAATGCGATTGTTTCTGCTTTCCGCAATCTGATTCCTTCAAGGGTCAGGATTATCGTGATGCTGACGATTATCGCGACC
CTGGTGATTTTTATCGATCAGCTGCTTAAAGCCTATCTGTTCGATATCAGTAAGCAGTTGAGTGTGTTTGTAGGACTGAT
TATCACCAACTGTATTGTTCTGGGACGGGCAGAGGCCTTCGCACTCAAGAACGGGGTGTGGCCGTCCATGCTCGACGGTC
TGGGCAACGGGCTGGGATATGGTATGATTCTGCTTTTTGTTTCCGCTATGAGGGAGCTTTTCGGCAGCGGAACCATGCTT
GGCTTTCAGATTGTTCCGGATATACTGTATGTCGAAAACGGAGGATGGTATATGAACAACGGTCTTATGCTGCTTGCCCC
CGGAGCATTTTTCGTGCTTGGCCTTCTGATCTGGCTGCAGCGCACACTGACCGGTTATACGGAGGAGTGA

Upstream 100 bases:

>100_bases
AGCATCGCTGACGACAGGGGGGATAAACCGTTTTCTGAAAGCGGATCTGATGAACTATCTGACGCTCCTCAGGGGTGGCA
ATTAACCGGTGTATAAAGGT

Downstream 100 bases:

>100_bases
TATGAGCGGATTGACCCATTATCTCAGCCTGGCGGTTGAGACCATCTTTATCAAGAATATTCTGCTGGCATATTTTCTCG
GGATGTGTTCGTTCCTTGCC

Product: NADH:ubiquinone oxidoreductase subunit D

Products: NA

Alternate protein names: Na(+)-NQR subunit D; Na(+)-translocating NQR subunit D; NQR complex subunit D; NQR-1 subunit D [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MVDKKTLKTLTEPVGMSNPITKQVLGICSALAVTVKMDTALVMSAALIFVLVGSNAIVSAFRNLIPSRVRIIVMLTIIAT
LVIFIDQLLKAYLFDISKQLSVFVGLIITNCIVLGRAEAFALKNGVWPSMLDGLGNGLGYGMILLFVSAMRELFGSGTML
GFQIVPDILYVENGGWYMNNGLMLLAPGAFFVLGLLIWLQRTLTGYTEE

Sequences:

>Translated_209_residues
MVDKKTLKTLTEPVGMSNPITKQVLGICSALAVTVKMDTALVMSAALIFVLVGSNAIVSAFRNLIPSRVRIIVMLTIIAT
LVIFIDQLLKAYLFDISKQLSVFVGLIITNCIVLGRAEAFALKNGVWPSMLDGLGNGLGYGMILLFVSAMRELFGSGTML
GFQIVPDILYVENGGWYMNNGLMLLAPGAFFVLGLLIWLQRTLTGYTEE
>Mature_209_residues
MVDKKTLKTLTEPVGMSNPITKQVLGICSALAVTVKMDTALVMSAALIFVLVGSNAIVSAFRNLIPSRVRIIVMLTIIAT
LVIFIDQLLKAYLFDISKQLSVFVGLIITNCIVLGRAEAFALKNGVWPSMLDGLGNGLGYGMILLFVSAMRELFGSGTML
GFQIVPDILYVENGGWYMNNGLMLLAPGAFFVLGLLIWLQRTLTGYTEE

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1347

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family [H]

Homologues:

Organism=Escherichia coli, GI1787919, Length=188, Percent_Identity=36.7021276595745, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003667
- InterPro:   IPR011292 [H]

Pfam domain/function: PF02508 Rnf-Nqr [H]

EC number: NA

Molecular weight: Translated: 22686; Mature: 22686

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDKKTLKTLTEPVGMSNPITKQVLGICSALAVTVKMDTALVMSAALIFVLVGSNAIVSA
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FRNLIPSRVRIIVMLTIIATLVIFIDQLLKAYLFDISKQLSVFVGLIITNCIVLGRAEAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALKNGVWPSMLDGLGNGLGYGMILLFVSAMRELFGSGTMLGFQIVPDILYVENGGWYMNN
HHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHCCEEEEECCCEEEEC
GLMLLAPGAFFVLGLLIWLQRTLTGYTEE
CEEEEECHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVDKKTLKTLTEPVGMSNPITKQVLGICSALAVTVKMDTALVMSAALIFVLVGSNAIVSA
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FRNLIPSRVRIIVMLTIIATLVIFIDQLLKAYLFDISKQLSVFVGLIITNCIVLGRAEAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALKNGVWPSMLDGLGNGLGYGMILLFVSAMRELFGSGTMLGFQIVPDILYVENGGWYMNN
HHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHCCEEEEECCCEEEEC
GLMLLAPGAFFVLGLLIWLQRTLTGYTEE
CEEEEECHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7805867; 7729558; 9490015; 10549856; 11248187; 11248188 [H]