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The map label for this gene is lepB [H]

Identifier: 194334373

GI number: 194334373

Start: 1706729

End: 1707598

Strand: Reverse

Name: lepB [H]

Synonym: Paes_1568

Alternate gene names: 194334373

Gene position: 1707598-1706729 (Counterclockwise)

Preceding gene: 194334374

Following gene: 194334371

Centisome position: 67.95

GC content: 49.2

Gene sequence:

>870_bases
ATGATCCTCCTTCGTCTTGTTTGCTTAATACGAAAAGATCTTATGGCTGTAAAAATACAGAAAACAGGAAAGCAGCACTC
CCGGGAGTGGTTTGAGGCGTTAATGATTGCGGCTGTTTTTGCTGCGATCATCAGGGTCTTCATTCTGGAGTCATACAGAA
TTCCAACCAGTTCTATGGAGAGTACTCTTCTTGCCGGGGATTTTCTGTTTGTCAACAAGTTTGTCTATGGTGCGAAAGTG
CCTATGACCGATTATCGTCTGCCCGCAGTCGATACGGTTGAGCGCGGTGATATCATTGTTTTCAAATTCCCCAAAGATCG
GTCGCTCAACTATATCAAGCGATGTGTAGCTCTTCCCGGTGATACGCTTGCGATTCGTGAACGTCAGCTTTTTGTCAACA
ATGCCGCAGTTCCTCTGCCCGAACATGCCCAGTTTCTCAATGAGATGGTCCCCGCCGGGCAGCCGGACCAACAGATTTTT
CCAAGGTATTCCGATTTCAACAAGGATAACTACGGACCGCTCAGGATTCCCGCTCAAGGCGATGTGCTGGAGCTCAACCG
CAATACCATTTACCTCTACGGTTCGCTTATTGCCGATGAGGGACACCGCGTGAGCGTTATGGGAGAGAGGATCATGATTG
ACGGGGTTCCTGCCACGAGCTATAGCGTGACACAGAACTATTATTTTGCCATGGGTGACAACCGGGATAACAGCCTTGAC
AGTCGTTACTGGGGCTTTCTGCCTGAAAAAGACATGATTGGTCAGGCATTGATGGTCTACTGGTCATGGGATCCGCATAT
TTCGCTGCTGAGCCCGATTGAAAAGATCGGCTCTATCCGCTGGAACCGGATGGCCCTGATGGTTCACTGA

Upstream 100 bases:

>100_bases
CGTTTCTTATGGTTTTTCCTGATTTTTTCATTGCTGATCCGCAAGGTAAACGGCAGAAGCATCGTCAAATAATCATCACA
ACAGAACACGTCGGGGCGGG

Downstream 100 bases:

>100_bases
GGCGGGGCGTCGCCAGAATTGGCTTGCGTCAGTTGCGGGTTGAGCTTGAGCAGATGTGCAGAAATAACCCTGATTGACTG
TGCTGCCTGTTTCCTGTTGA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MILLRLVCLIRKDLMAVKIQKTGKQHSREWFEALMIAAVFAAIIRVFILESYRIPTSSMESTLLAGDFLFVNKFVYGAKV
PMTDYRLPAVDTVERGDIIVFKFPKDRSLNYIKRCVALPGDTLAIRERQLFVNNAAVPLPEHAQFLNEMVPAGQPDQQIF
PRYSDFNKDNYGPLRIPAQGDVLELNRNTIYLYGSLIADEGHRVSVMGERIMIDGVPATSYSVTQNYYFAMGDNRDNSLD
SRYWGFLPEKDMIGQALMVYWSWDPHISLLSPIEKIGSIRWNRMALMVH

Sequences:

>Translated_289_residues
MILLRLVCLIRKDLMAVKIQKTGKQHSREWFEALMIAAVFAAIIRVFILESYRIPTSSMESTLLAGDFLFVNKFVYGAKV
PMTDYRLPAVDTVERGDIIVFKFPKDRSLNYIKRCVALPGDTLAIRERQLFVNNAAVPLPEHAQFLNEMVPAGQPDQQIF
PRYSDFNKDNYGPLRIPAQGDVLELNRNTIYLYGSLIADEGHRVSVMGERIMIDGVPATSYSVTQNYYFAMGDNRDNSLD
SRYWGFLPEKDMIGQALMVYWSWDPHISLLSPIEKIGSIRWNRMALMVH
>Mature_289_residues
MILLRLVCLIRKDLMAVKIQKTGKQHSREWFEALMIAAVFAAIIRVFILESYRIPTSSMESTLLAGDFLFVNKFVYGAKV
PMTDYRLPAVDTVERGDIIVFKFPKDRSLNYIKRCVALPGDTLAIRERQLFVNNAAVPLPEHAQFLNEMVPAGQPDQQIF
PRYSDFNKDNYGPLRIPAQGDVLELNRNTIYLYGSLIADEGHRVSVMGERIMIDGVPATSYSVTQNYYFAMGDNRDNSLD
SRYWGFLPEKDMIGQALMVYWSWDPHISLLSPIEKIGSIRWNRMALMVH

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=238, Percent_Identity=33.6134453781513, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 33108; Mature: 33108

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLRLVCLIRKDLMAVKIQKTGKQHSREWFEALMIAAVFAAIIRVFILESYRIPTSSME
CHHHHHHHHHHHHHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
STLLAGDFLFVNKFVYGAKVPMTDYRLPAVDTVERGDIIVFKFPKDRSLNYIKRCVALPG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCC
DTLAIRERQLFVNNAAVPLPEHAQFLNEMVPAGQPDQQIFPRYSDFNKDNYGPLRIPAQG
CEEEEEHEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCEEECCCC
DVLELNRNTIYLYGSLIADEGHRVSVMGERIMIDGVPATSYSVTQNYYFAMGDNRDNSLD
CEEEECCCEEEEEEEEEECCCCEEEEECCEEEEECCCCCCEEEECCEEEEECCCCCCCCC
SRYWGFLPEKDMIGQALMVYWSWDPHISLLSPIEKIGSIRWNRMALMVH
CHHCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEC
>Mature Secondary Structure
MILLRLVCLIRKDLMAVKIQKTGKQHSREWFEALMIAAVFAAIIRVFILESYRIPTSSME
CHHHHHHHHHHHHHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
STLLAGDFLFVNKFVYGAKVPMTDYRLPAVDTVERGDIIVFKFPKDRSLNYIKRCVALPG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCC
DTLAIRERQLFVNNAAVPLPEHAQFLNEMVPAGQPDQQIFPRYSDFNKDNYGPLRIPAQG
CEEEEEHEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCEEECCCC
DVLELNRNTIYLYGSLIADEGHRVSVMGERIMIDGVPATSYSVTQNYYFAMGDNRDNSLD
CEEEECCCEEEEEEEEEECCCCEEEEECCEEEEECCCCCCEEEECCEEEEECCCCCCCCC
SRYWGFLPEKDMIGQALMVYWSWDPHISLLSPIEKIGSIRWNRMALMVH
CHHCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]