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The map label for this gene is pkn1 [H]

Identifier: 194334133

GI number: 194334133

Start: 1440266

End: 1441078

Strand: Reverse

Name: pkn1 [H]

Synonym: Paes_1321

Alternate gene names: 194334133

Gene position: 1441078-1440266 (Counterclockwise)

Preceding gene: 194334134

Following gene: 194334132

Centisome position: 57.35

GC content: 59.41

Gene sequence:

>813_bases
ATGACATCGCCAACACGTAACGAAACACTTGCGGAACTCAGAAGCCGCGCGATTCAGCCTTTCAGCAGCGAGCTATCGCC
GGTCATCGTCAACGAGCAGGATGGCTCCCCGATGGTGCTGGTTCCCGCTGGGCGCTTCACCATGGGCGACGACCTCGACA
AGGAGAGTCCGCAACAGAGCGTCTTTCTCAAGGCGTTCTATATCTCGATTTACGCGGTTACCAATCGCCAGTATCGGGCG
TTCATGGAGGCTACAGGTCACCGGCCACCCAACATCGGAGCAAGGATAGATTCGCTTTCGGTCTGGCACGAAGAGGGCTG
TCCCGAAGCCTTCGACGATTACCCGGTCGTGCTTATCAGCTGGGACGATGCGGACGCCTATGCCAGATGGGCGGGATGCC
GGTTGCCCAACGAAGCCGAGTGGGAAAAAGCTGCGCGCGGGCCGGAAGGACTGATCTACCCGTGGGGGGAGCGGTGGGAT
GAAAATAACTGCCGGAACCGCAACAACCGGGGCGAGGACTCGGTTGCACTGGTGTACGCCTATCCCGAAGGCGTCTCGGG
CTACGGTACCTGGAACCAGAGCGGTAACATTATGGAGTGGTGCTCGATCTGGGAAGGGGAGGACGATTCCGGGAACGCTT
CATCCGGAGAAGAAGCTCTATGCCAGGAACGGGGTGGCTGCTGGCGCTATCCCGATAAGTTCGCATTCCGCGCATCGCAG
CGGTCATTTGTGGTACCGAAAGCGGTCAACGATTTTCGGGGATTCCGGCTGGTGTTGCCGGTTGAGTCGGGAGGTGGAAG
GGAGGACGGTTGA

Upstream 100 bases:

>100_bases
TGATCGACGAGTTGCGGGAGATGGTCCAGAACGGCCAGGTGCGCAATGCATCCGTCGAATCGGGCGACGTGCCTGCGTCA
AAGAAAACCGGAGATCCACA

Downstream 100 bases:

>100_bases
TGAGTGATAGGAAACGTTGTGTATGAGATTGAATAGTTGGTTTCGCTTTGTATTTTGAAAAGAGGGAAAACCATCTTCTT
TCAGGAAACGGTAAGCAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTSPTRNETLAELRSRAIQPFSSELSPVIVNEQDGSPMVLVPAGRFTMGDDLDKESPQQSVFLKAFYISIYAVTNRQYRA
FMEATGHRPPNIGARIDSLSVWHEEGCPEAFDDYPVVLISWDDADAYARWAGCRLPNEAEWEKAARGPEGLIYPWGERWD
ENNCRNRNNRGEDSVALVYAYPEGVSGYGTWNQSGNIMEWCSIWEGEDDSGNASSGEEALCQERGGCWRYPDKFAFRASQ
RSFVVPKAVNDFRGFRLVLPVESGGGREDG

Sequences:

>Translated_270_residues
MTSPTRNETLAELRSRAIQPFSSELSPVIVNEQDGSPMVLVPAGRFTMGDDLDKESPQQSVFLKAFYISIYAVTNRQYRA
FMEATGHRPPNIGARIDSLSVWHEEGCPEAFDDYPVVLISWDDADAYARWAGCRLPNEAEWEKAARGPEGLIYPWGERWD
ENNCRNRNNRGEDSVALVYAYPEGVSGYGTWNQSGNIMEWCSIWEGEDDSGNASSGEEALCQERGGCWRYPDKFAFRASQ
RSFVVPKAVNDFRGFRLVLPVESGGGREDG
>Mature_269_residues
TSPTRNETLAELRSRAIQPFSSELSPVIVNEQDGSPMVLVPAGRFTMGDDLDKESPQQSVFLKAFYISIYAVTNRQYRAF
MEATGHRPPNIGARIDSLSVWHEEGCPEAFDDYPVVLISWDDADAYARWAGCRLPNEAEWEKAARGPEGLIYPWGERWDE
NNCRNRNNRGEDSVALVYAYPEGVSGYGTWNQSGNIMEWCSIWEGEDDSGNASSGEEALCQERGGCWRYPDKFAFRASQR
SFVVPKAVNDFRGFRLVLPVESGGGREDG

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=264, Percent_Identity=34.0909090909091, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI38202250, Length=289, Percent_Identity=31.8339100346021, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI257470977, Length=275, Percent_Identity=32.7272727272727, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI194248087, Length=202, Percent_Identity=32.1782178217822, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI194248088, Length=214, Percent_Identity=30.3738317757009, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI20130397, Length=265, Percent_Identity=29.811320754717, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 30301; Mature: 30169

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTRNETLAELRSRAIQPFSSELSPVIVNEQDGSPMVLVPAGRFTMGDDLDKESPQQS
CCCCCCHHHHHHHHHHHCCCHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCHHH
VFLKAFYISIYAVTNRQYRAFMEATGHRPPNIGARIDSLSVWHEEGCPEAFDDYPVVLIS
HHHEEEEEEEEEECCHHHHHHHHHHCCCCCCCCCEECCEEEHHHCCCCCCCCCCCEEEEE
WDDADAYARWAGCRLPNEAEWEKAARGPEGLIYPWGERWDENNCRNRNNRGEDSVALVYA
ECCCHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEE
YPEGVSGYGTWNQSGNIMEWCSIWEGEDDSGNASSGEEALCQERGGCWRYPDKFAFRASQ
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHEECCC
RSFVVPKAVNDFRGFRLVLPVESGGGREDG
CCEECCHHHHCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TSPTRNETLAELRSRAIQPFSSELSPVIVNEQDGSPMVLVPAGRFTMGDDLDKESPQQS
CCCCCHHHHHHHHHHHCCCHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCHHH
VFLKAFYISIYAVTNRQYRAFMEATGHRPPNIGARIDSLSVWHEEGCPEAFDDYPVVLIS
HHHEEEEEEEEEECCHHHHHHHHHHCCCCCCCCCEECCEEEHHHCCCCCCCCCCCEEEEE
WDDADAYARWAGCRLPNEAEWEKAARGPEGLIYPWGERWDENNCRNRNNRGEDSVALVYA
ECCCHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEE
YPEGVSGYGTWNQSGNIMEWCSIWEGEDDSGNASSGEEALCQERGGCWRYPDKFAFRASQ
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHEECCC
RSFVVPKAVNDFRGFRLVLPVESGGGREDG
CCEECCHHHHCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]