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The map label for this gene is cobL [H]

Identifier: 194334101

GI number: 194334101

Start: 1407598

End: 1408800

Strand: Reverse

Name: cobL [H]

Synonym: Paes_1289

Alternate gene names: 194334101

Gene position: 1408800-1407598 (Counterclockwise)

Preceding gene: 194334102

Following gene: 194334100

Centisome position: 56.06

GC content: 61.26

Gene sequence:

>1203_bases
ATGTCTGAGAAGTTTCTTGTGATCGGCCTCAGTGACAGCCGTTCCCCGGTTTTCGATCCTCAAACCCTGCGAGAGATCGC
CGCATGCAGGGTGTTTGCCGGAGGTGAGCGGCATCGCGCCATCGTCGGGCATCTGCTGCCGCACGCCAGCCGATGGATTA
CCATCGCACCTCCTATGAGTGACGTGATGCGACAGCTGGATGAAGCCGGAGGCCGGGTCGTGGTGTTTGCCTCCGGAGAT
CCGCTCTTTTACGGCTTCGGAGCGACCCTGCAGAAACACTTTCCGGATGCATCCTGCCGTTTTGTTCCGGCGTTTTCCTC
GCTGCAGACACTTGCGCACCGGCTTCAGCTGCCGTATCAGTCAATGCGTTTCGCCTCCCTGACCGGGAGGAGCTGGCAGG
AACTCGATCGTCTGCTCATCGAAGGAGCCGGTCTTATCGGCGTGCTGACTGACAGGCGCAAAACGCCTGCAGCGATTGCG
CGCCGTCTTCTCGAATACGGCTACGGGGGGTATTCGCTGCTCGTCGGCGAGGCTCTCGGGGGGCCTGAAGAACGGGTGAC
GGAGCTTTCGCCGGCAGACGCATCGGACGCGCTCTTTGACGATCTCAACTGCGTCATTCTCCGGGGCGGCCCTTCCCGGG
AGCGATTCTACGGTATTGCCGATTCGCTGTTCGAAGGGCTTCCGGGCCGGCCGGATATGATCACGAAGATGCCGCTTCGC
CTGGCAACGCTTTCACGACTCAACCTGGTGAACTGTTCGCACTTCTGGGATATCGGCTTCTGCACCGGATCGGTATCCAT
CGAGGCCCGGCTGCAGTTTCCCGGGCTGGAGATCAGCGCATTTGAAAAGCGCCCCGAATGCGAAGGGATCTTCGATCGCA
ATGCCAGGCGGTTCGGGGCTCCGGGAGTTCGGGTGGTGATGGGTGACGTGCTGAAGCAGGAGTTTGACGAACATACCGGG
CCGGACGGCAGGGTAGGAGCCGTGTTCATCGGCGGGCACGGGGGGCAGCTCGAGGCGATCTTCGATATCGCAGCCGAGCG
GCTTTCGCCCGGCGGACGGATTGTGGTCAACGCTGTCAGGACAGACACCCTCGAACGCTTTCATGCGCGGGCCCGGCACC
ATGCGCTTCGCCTGCCCGATGACCTTGTGATCACTCCCGGGAGGCATAATTCAATAACCATCGCTGCCGCAGTGCAGGAA
TAA

Upstream 100 bases:

>100_bases
GTGGTGATCGAAGGCCGCAAGGGAGGCAGTTCGGTTGCCGCGACCATCGTGAACGCGGCAATGAGCCTCGAGGATGCCCA
GGCAATGAAACCGGGAAGAG

Downstream 100 bases:

>100_bases
CTACATGTGTTTCTATGTCATCAGACCGCCTCGCTATTATCGCCGCTTCTCAGCAGGGAATCATGACCGCTTTACGCCTG
AAACAGGAACTCGCAGCGTG

Product: precorrin-6y C5,15-methyltransferase subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSEKFLVIGLSDSRSPVFDPQTLREIAACRVFAGGERHRAIVGHLLPHASRWITIAPPMSDVMRQLDEAGGRVVVFASGD
PLFYGFGATLQKHFPDASCRFVPAFSSLQTLAHRLQLPYQSMRFASLTGRSWQELDRLLIEGAGLIGVLTDRRKTPAAIA
RRLLEYGYGGYSLLVGEALGGPEERVTELSPADASDALFDDLNCVILRGGPSRERFYGIADSLFEGLPGRPDMITKMPLR
LATLSRLNLVNCSHFWDIGFCTGSVSIEARLQFPGLEISAFEKRPECEGIFDRNARRFGAPGVRVVMGDVLKQEFDEHTG
PDGRVGAVFIGGHGGQLEAIFDIAAERLSPGGRIVVNAVRTDTLERFHARARHHALRLPDDLVITPGRHNSITIAAAVQE

Sequences:

>Translated_400_residues
MSEKFLVIGLSDSRSPVFDPQTLREIAACRVFAGGERHRAIVGHLLPHASRWITIAPPMSDVMRQLDEAGGRVVVFASGD
PLFYGFGATLQKHFPDASCRFVPAFSSLQTLAHRLQLPYQSMRFASLTGRSWQELDRLLIEGAGLIGVLTDRRKTPAAIA
RRLLEYGYGGYSLLVGEALGGPEERVTELSPADASDALFDDLNCVILRGGPSRERFYGIADSLFEGLPGRPDMITKMPLR
LATLSRLNLVNCSHFWDIGFCTGSVSIEARLQFPGLEISAFEKRPECEGIFDRNARRFGAPGVRVVMGDVLKQEFDEHTG
PDGRVGAVFIGGHGGQLEAIFDIAAERLSPGGRIVVNAVRTDTLERFHARARHHALRLPDDLVITPGRHNSITIAAAVQE
>Mature_399_residues
SEKFLVIGLSDSRSPVFDPQTLREIAACRVFAGGERHRAIVGHLLPHASRWITIAPPMSDVMRQLDEAGGRVVVFASGDP
LFYGFGATLQKHFPDASCRFVPAFSSLQTLAHRLQLPYQSMRFASLTGRSWQELDRLLIEGAGLIGVLTDRRKTPAAIAR
RLLEYGYGGYSLLVGEALGGPEERVTELSPADASDALFDDLNCVILRGGPSRERFYGIADSLFEGLPGRPDMITKMPLRL
ATLSRLNLVNCSHFWDIGFCTGSVSIEARLQFPGLEISAFEKRPECEGIFDRNARRFGAPGVRVVMGDVLKQEFDEHTGP
DGRVGAVFIGGHGGQLEAIFDIAAERLSPGGRIVVNAVRTDTLERFHARARHHALRLPDDLVITPGRHNSITIAAAVQE

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43826; Mature: 43695

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKFLVIGLSDSRSPVFDPQTLREIAACRVFAGGERHRAIVGHLLPHASRWITIAPPMS
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCHH
DVMRQLDEAGGRVVVFASGDPLFYGFGATLQKHFPDASCRFVPAFSSLQTLAHRLQLPYQ
HHHHHHHHCCCEEEEEECCCCEEEECCCHHHHHCCCCCCEEEECHHHHHHHHHHHHCCHH
SMRFASLTGRSWQELDRLLIEGAGLIGVLTDRRKTPAAIARRLLEYGYGGYSLLVGEALG
HHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEHHCC
GPEERVTELSPADASDALFDDLNCVILRGGPSRERFYGIADSLFEGLPGRPDMITKMPLR
CCHHHHHCCCCCCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCHH
LATLSRLNLVNCSHFWDIGFCTGSVSIEARLQFPGLEISAFEKRPECEGIFDRNARRFGA
HHHHHHCCEECCCCEEEEEEEECCEEEEEEEECCCCEEECCCCCCCCCCHHCCCCHHCCC
PGVRVVMGDVLKQEFDEHTGPDGRVGAVFIGGHGGQLEAIFDIAAERLSPGGRIVVNAVR
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEHH
TDTLERFHARARHHALRLPDDLVITPGRHNSITIAAAVQE
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEECC
>Mature Secondary Structure 
SEKFLVIGLSDSRSPVFDPQTLREIAACRVFAGGERHRAIVGHLLPHASRWITIAPPMS
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCHH
DVMRQLDEAGGRVVVFASGDPLFYGFGATLQKHFPDASCRFVPAFSSLQTLAHRLQLPYQ
HHHHHHHHCCCEEEEEECCCCEEEECCCHHHHHCCCCCCEEEECHHHHHHHHHHHHCCHH
SMRFASLTGRSWQELDRLLIEGAGLIGVLTDRRKTPAAIARRLLEYGYGGYSLLVGEALG
HHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEHHCC
GPEERVTELSPADASDALFDDLNCVILRGGPSRERFYGIADSLFEGLPGRPDMITKMPLR
CCHHHHHCCCCCCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCHH
LATLSRLNLVNCSHFWDIGFCTGSVSIEARLQFPGLEISAFEKRPECEGIFDRNARRFGA
HHHHHHCCEECCCCEEEEEEEECCEEEEEEEECCCCEEECCCCCCCCCCHHCCCCHHCCC
PGVRVVMGDVLKQEFDEHTGPDGRVGAVFIGGHGGQLEAIFDIAAERLSPGGRIVVNAVR
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEHH
TDTLERFHARARHHALRLPDDLVITPGRHNSITIAAAVQE
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]