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The map label for this gene is ynfJ [C]

Identifier: 194334000

GI number: 194334000

Start: 1293319

End: 1295205

Strand: Reverse

Name: ynfJ [C]

Synonym: Paes_1184

Alternate gene names: 194334000

Gene position: 1295205-1293319 (Counterclockwise)

Preceding gene: 194334003

Following gene: 194333993

Centisome position: 51.54

GC content: 50.72

Gene sequence:

>1887_bases
ATGAAAGATTCCTCGAACATAAATGGTAAATGGAACAGGAAATTCCTTGCCGTTTTTTATGATTTTTTTCGCAAAAGCCG
CTATTTCCAGGGATCGTCTCAGAAGTATTTCAGATTGACCCTGGACAATGTTCTTCTCCATCTCAACCTCAATCAGGATC
TTCCTTTTTTATTCGTGGCCGTGTTCATTGGTATTACGACCGGCTATGTCGCTGTCGTATTTCACGACGCGATCAAGTTC
CTCAGTCATTTTTTCTTTGGTGGTATCGAGGCTTTCGGCACATCCATTCTCATTGACGAATACTGGTTTTTTTTTATGCC
GCTCGTTCCGGCAGCGGGGGGGCTGCTGGTGGGGTTGTACAATGTGTATGTTGTTAAAACAACCCAGCCCGGCCATGGGC
TTGCAAGCGTGATCAAGGCAGTCGCGCAGAACAATGGCATCATTGGCAGGAATCTCTGGCTGCATCGTACGATCACTTCT
GTTCTCACTATTGGTACCGGGGGTGGCGGAGGCCGAGAGGCCCCGATAGCCCAGGTAGGGGCGGCTCTTGGTTCCTCGGT
CGCCCAGATGCTGAAATTTTCTCCCGACAGAACAAGAACCCTGCTTGGCTGCGGAGCTGCGGCCGGGCTGGCGGCGGTAT
TTAACGCGCCTCTCGGGGGTGTGATGTTTGCCATCGAGGTTATTCTCGGGGATTTCAGCGTGCGTACCTTCAGCCCGATC
GTTATTGCCGCTGTGATCGGTACCGTTGTTTCCCGCGGTTATCTCGGTAATTCCCCTACCTTCCAGGTTCCCGACTACAG
TCTTGTTTCAAATTCTGAACTGGTTTTTTACTTCTGTCTCGGTGTCCTGGCCGGACTGTCCGCTGTTTTGTTCATTAAGA
TGTATTACCGAATAGAGGAGGGATTTCAGACGATCCGCAAGAAGCATAACATTCCTCTCTGGGCTATGCCCGCCATAGGA
GGGCTTCTCAGCGGTCTTATCTGCATGTGGTTGCCGGGGCTCTATGGTTATAGCTACGAAGCGATCGACAATGCTGTGCG
GGGGACCGAGTCGTGGATCACTATGGCCGGGATCTATTTTCTCAAGCCCGTTGTTGCCGGGTTGAGCGTTGGCTCGGGCG
GCTCGGGCGGCATGTTTGCACCGGCAATGAAGATGGGCGCAATGCTGGGAGGCATGTTCGGCAATCTGGTGCACTATCTT
TTTCCTGCTATCACAGCGGCATCAGGCGCCTACGCACTGGTCGGCATGGGGGCTTTGACTGCCGGTATCATGCGTGCGCC
GTTGACGGTTATTCTGATTTTGTTTGAAGTGACCGGCGAGTATGAGATTGTGTTGCCGATCATGTTCGCCGCGGTTACTG
CCGCCCTGATTGCACGTCTTGCCTACAGTTATTCTATGGAAACCTATGTGCTCGAGAAAGAGGGGGTTCGCGTAGGCTAT
GGTATTGCGCTTTCAGTCGCAGAGAATATCAGTGTCCTTGATGTCATGAGAACGAACTATGTCCGTTTTCGTGATGTTAC
CAGGGCTGATAAGATTGTCGATGTGTTTCATAATACGCCGGAATCGAATTTTCTTGTCACCAATGAAGCTAACGAGTTTG
TTGGCATTATCAGGCTTGACGAGATGAGCATTCTTTTGAAGGAGGGGATGTTTACCGGTCTTATCGCAGAGGATATTGTC
AAGAAAGAGGTTCCTGTTCTTTATGATACCTCGAAACTCGATGAGGCACTGAAGCTCTTTGAACTTTCCGATTACGATAT
TCTTCCCGTGCTGTCCCAGAAGTCATCCGAGCTGCTCGGGGTTGTCAGGCAGGAACAGGCCTTCTCCTATTATCGTAAAC
AGATGAACCTCTACGGTTCCGATCTTGATGCCAAGCAGTCAGGCTAA

Upstream 100 bases:

>100_bases
TGTTTATTTTTCCTGCCTGTAACAAGGCTCTCCGCACTGGCCGTTACAGGGCGGCTTTTTCCGGACTGGCGTGTATGCCT
GGAGAGTTGAAATCCCGTTC

Downstream 100 bases:

>100_bases
GCTCGTTTTGCCTGTTGTGTAAGTACGATGATCAGTATGATAGTGACTGCCTGGCCGATCATGAAGATATCCTTCGGCAC
ATAGGCGTTGATACTCAGGC

Product: chloride channel core protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MKDSSNINGKWNRKFLAVFYDFFRKSRYFQGSSQKYFRLTLDNVLLHLNLNQDLPFLFVAVFIGITTGYVAVVFHDAIKF
LSHFFFGGIEAFGTSILIDEYWFFFMPLVPAAGGLLVGLYNVYVVKTTQPGHGLASVIKAVAQNNGIIGRNLWLHRTITS
VLTIGTGGGGGREAPIAQVGAALGSSVAQMLKFSPDRTRTLLGCGAAAGLAAVFNAPLGGVMFAIEVILGDFSVRTFSPI
VIAAVIGTVVSRGYLGNSPTFQVPDYSLVSNSELVFYFCLGVLAGLSAVLFIKMYYRIEEGFQTIRKKHNIPLWAMPAIG
GLLSGLICMWLPGLYGYSYEAIDNAVRGTESWITMAGIYFLKPVVAGLSVGSGGSGGMFAPAMKMGAMLGGMFGNLVHYL
FPAITAASGAYALVGMGALTAGIMRAPLTVILILFEVTGEYEIVLPIMFAAVTAALIARLAYSYSMETYVLEKEGVRVGY
GIALSVAENISVLDVMRTNYVRFRDVTRADKIVDVFHNTPESNFLVTNEANEFVGIIRLDEMSILLKEGMFTGLIAEDIV
KKEVPVLYDTSKLDEALKLFELSDYDILPVLSQKSSELLGVVRQEQAFSYYRKQMNLYGSDLDAKQSG

Sequences:

>Translated_628_residues
MKDSSNINGKWNRKFLAVFYDFFRKSRYFQGSSQKYFRLTLDNVLLHLNLNQDLPFLFVAVFIGITTGYVAVVFHDAIKF
LSHFFFGGIEAFGTSILIDEYWFFFMPLVPAAGGLLVGLYNVYVVKTTQPGHGLASVIKAVAQNNGIIGRNLWLHRTITS
VLTIGTGGGGGREAPIAQVGAALGSSVAQMLKFSPDRTRTLLGCGAAAGLAAVFNAPLGGVMFAIEVILGDFSVRTFSPI
VIAAVIGTVVSRGYLGNSPTFQVPDYSLVSNSELVFYFCLGVLAGLSAVLFIKMYYRIEEGFQTIRKKHNIPLWAMPAIG
GLLSGLICMWLPGLYGYSYEAIDNAVRGTESWITMAGIYFLKPVVAGLSVGSGGSGGMFAPAMKMGAMLGGMFGNLVHYL
FPAITAASGAYALVGMGALTAGIMRAPLTVILILFEVTGEYEIVLPIMFAAVTAALIARLAYSYSMETYVLEKEGVRVGY
GIALSVAENISVLDVMRTNYVRFRDVTRADKIVDVFHNTPESNFLVTNEANEFVGIIRLDEMSILLKEGMFTGLIAEDIV
KKEVPVLYDTSKLDEALKLFELSDYDILPVLSQKSSELLGVVRQEQAFSYYRKQMNLYGSDLDAKQSG
>Mature_628_residues
MKDSSNINGKWNRKFLAVFYDFFRKSRYFQGSSQKYFRLTLDNVLLHLNLNQDLPFLFVAVFIGITTGYVAVVFHDAIKF
LSHFFFGGIEAFGTSILIDEYWFFFMPLVPAAGGLLVGLYNVYVVKTTQPGHGLASVIKAVAQNNGIIGRNLWLHRTITS
VLTIGTGGGGGREAPIAQVGAALGSSVAQMLKFSPDRTRTLLGCGAAAGLAAVFNAPLGGVMFAIEVILGDFSVRTFSPI
VIAAVIGTVVSRGYLGNSPTFQVPDYSLVSNSELVFYFCLGVLAGLSAVLFIKMYYRIEEGFQTIRKKHNIPLWAMPAIG
GLLSGLICMWLPGLYGYSYEAIDNAVRGTESWITMAGIYFLKPVVAGLSVGSGGSGGMFAPAMKMGAMLGGMFGNLVHYL
FPAITAASGAYALVGMGALTAGIMRAPLTVILILFEVTGEYEIVLPIMFAAVTAALIARLAYSYSMETYVLEKEGVRVGY
GIALSVAENISVLDVMRTNYVRFRDVTRADKIVDVFHNTPESNFLVTNEANEFVGIIRLDEMSILLKEGMFTGLIAEDIV
KKEVPVLYDTSKLDEALKLFELSDYDILPVLSQKSSELLGVVRQEQAFSYYRKQMNLYGSDLDAKQSG

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557473, Length=410, Percent_Identity=27.0731707317073, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI189217923, Length=410, Percent_Identity=27.0731707317073, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI189217921, Length=410, Percent_Identity=27.0731707317073, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI153252026, Length=376, Percent_Identity=26.5957446808511, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI87081943, Length=350, Percent_Identity=30.2857142857143, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1786350, Length=328, Percent_Identity=31.7073170731707, Blast_Score=118, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71996452, Length=520, Percent_Identity=22.6923076923077, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71996455, Length=520, Percent_Identity=22.6923076923077, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 68378; Mature: 68378

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSSNINGKWNRKFLAVFYDFFRKSRYFQGSSQKYFRLTLDNVLLHLNLNQDLPFLFVA
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEECCCCCHHHHHH
VFIGITTGYVAVVFHDAIKFLSHFFFGGIEAFGTSILIDEYWFFFMPLVPAAGGLLVGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHCCCHHHEEEE
NVYVVKTTQPGHGLASVIKAVAQNNGIIGRNLWLHRTITSVLTIGTGGGGGREAPIAQVG
EEEEEEECCCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHEECCCCCCCCCCHHHHHH
AALGSSVAQMLKFSPDRTRTLLGCGAAAGLAAVFNAPLGGVMFAIEVILGDFSVRTFSPI
HHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHH
VIAAVIGTVVSRGYLGNSPTFQVPDYSLVSNSELVFYFCLGVLAGLSAVLFIKMYYRIEE
HHHHHHHHHHHCCCCCCCCCEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFQTIRKKHNIPLWAMPAIGGLLSGLICMWLPGLYGYSYEAIDNAVRGTESWITMAGIYF
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHH
LKPVVAGLSVGSGGSGGMFAPAMKMGAMLGGMFGNLVHYLFPAITAASGAYALVGMGALT
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGIMRAPLTVILILFEVTGEYEIVLPIMFAAVTAALIARLAYSYSMETYVLEKEGVRVGY
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHEEEEECCCCEEEC
GIALSVAENISVLDVMRTNYVRFRDVTRADKIVDVFHNTPESNFLVTNEANEFVGIIRLD
EEEEEHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEC
EMSILLKEGMFTGLIAEDIVKKEVPVLYDTSKLDEALKLFELSDYDILPVLSQKSSELLG
HHHHHHHCCCHHHHHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCCEEHHHCCCHHHHHH
VVRQEQAFSYYRKQMNLYGSDLDAKQSG
HHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKDSSNINGKWNRKFLAVFYDFFRKSRYFQGSSQKYFRLTLDNVLLHLNLNQDLPFLFVA
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEECCCCCHHHHHH
VFIGITTGYVAVVFHDAIKFLSHFFFGGIEAFGTSILIDEYWFFFMPLVPAAGGLLVGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHCCCHHHEEEE
NVYVVKTTQPGHGLASVIKAVAQNNGIIGRNLWLHRTITSVLTIGTGGGGGREAPIAQVG
EEEEEEECCCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHEECCCCCCCCCCHHHHHH
AALGSSVAQMLKFSPDRTRTLLGCGAAAGLAAVFNAPLGGVMFAIEVILGDFSVRTFSPI
HHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHH
VIAAVIGTVVSRGYLGNSPTFQVPDYSLVSNSELVFYFCLGVLAGLSAVLFIKMYYRIEE
HHHHHHHHHHHCCCCCCCCCEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFQTIRKKHNIPLWAMPAIGGLLSGLICMWLPGLYGYSYEAIDNAVRGTESWITMAGIYF
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHH
LKPVVAGLSVGSGGSGGMFAPAMKMGAMLGGMFGNLVHYLFPAITAASGAYALVGMGALT
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGIMRAPLTVILILFEVTGEYEIVLPIMFAAVTAALIARLAYSYSMETYVLEKEGVRVGY
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHEEEEECCCCEEEC
GIALSVAENISVLDVMRTNYVRFRDVTRADKIVDVFHNTPESNFLVTNEANEFVGIIRLD
EEEEEHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEC
EMSILLKEGMFTGLIAEDIVKKEVPVLYDTSKLDEALKLFELSDYDILPVLSQKSSELLG
HHHHHHHCCCHHHHHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCCEEHHHCCCHHHHHH
VVRQEQAFSYYRKQMNLYGSDLDAKQSG
HHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]