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The map label for this gene is hslV

Identifier: 194333991

GI number: 194333991

Start: 1284073

End: 1284621

Strand: Reverse

Name: hslV

Synonym: Paes_1175

Alternate gene names: 194333991

Gene position: 1284621-1284073 (Counterclockwise)

Preceding gene: 194333992

Following gene: 194333990

Centisome position: 51.12

GC content: 50.09

Gene sequence:

>549_bases
ATGAACAGGAGTGAGAAACCGCAATTGAGGGCAACAACGGTTCTTGGGGTTATTCGAAACGGCAAGGCCGCTCTGGGCAG
CGACGGACAGATGACCCTCGGCAATACGGTTATCAAACATTCAACGAAAAAAATCCGCAGGATTCAACACGCGAACCTTA
TTACAGGTTTTGCAGGAGCGACCGCTGATGCCGTGACGCTTCTTGACCGTTTCGACGAAAAACTCCAGGCTTTCGGCGGT
CAGCTTGAACGTTCGGCCGTTGAACTCGCCCGTGACTGGCGAACCGATAAGTACCTTCGCAGACTTGAAGCTATGCTGGC
GGTTGTGAGCGCGGATAAAGCCTTGATTATTTCAGGAACAGGAGATGTGATAGAGCCTGAAGATGGTATTGTTGCTATCG
GGAGCGGAAGTATGTATGCGCTTTCTGCGGCAAGAGCGCTCATACGCTATACTGATCTCAGTGCCCGTGAAATTGTTACC
GAAAGTCTGAAGATCGCTGCCGATATCTGTATCTATACCAATGATCATATCGTCGTTGAAGAGGTCTGA

Upstream 100 bases:

>100_bases
TACAACGATGGGATAATCTCTCCCGAGGTGGCTTTAAACGGTCAGTTTTGCCGATTACCGTCGTCGATTGATTCGTTACT
AATTTTATTACGGAGTGTAG

Downstream 100 bases:

>100_bases
GCAGAAGGCAATCCTTCTGTTTCAATCAAAAAAATCATAAAAACGCAGAAAACTGATGATAGAGAAGACTGGTCATGAAG
AGATGCATGACGACAGTACC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MNRSEKPQLRATTVLGVIRNGKAALGSDGQMTLGNTVIKHSTKKIRRIQHANLITGFAGATADAVTLLDRFDEKLQAFGG
QLERSAVELARDWRTDKYLRRLEAMLAVVSADKALIISGTGDVIEPEDGIVAIGSGSMYALSAARALIRYTDLSAREIVT
ESLKIAADICIYTNDHIVVEEV

Sequences:

>Translated_182_residues
MNRSEKPQLRATTVLGVIRNGKAALGSDGQMTLGNTVIKHSTKKIRRIQHANLITGFAGATADAVTLLDRFDEKLQAFGG
QLERSAVELARDWRTDKYLRRLEAMLAVVSADKALIISGTGDVIEPEDGIVAIGSGSMYALSAARALIRYTDLSAREIVT
ESLKIAADICIYTNDHIVVEEV
>Mature_182_residues
MNRSEKPQLRATTVLGVIRNGKAALGSDGQMTLGNTVIKHSTKKIRRIQHANLITGFAGATADAVTLLDRFDEKLQAFGG
QLERSAVELARDWRTDKYLRRLEAMLAVVSADKALIISGTGDVIEPEDGIVAIGSGSMYALSAARALIRYTDLSAREIVT
ESLKIAADICIYTNDHIVVEEV

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=54.9707602339181, Blast_Score=194, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_PROA2 (B4S817)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002015851.1
- ProteinModelPortal:   B4S817
- SMR:   B4S817
- GeneID:   6459927
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_1175
- HOGENOM:   HBG288822
- OMA:   AADICVY
- ProtClustDB:   PRK05456
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19727; Mature: 19727

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: ACT_SITE 12-12

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSEKPQLRATTVLGVIRNGKAALGSDGQMTLGNTVIKHSTKKIRRIQHANLITGFAGA
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCC
TADAVTLLDRFDEKLQAFGGQLERSAVELARDWRTDKYLRRLEAMLAVVSADKALIISGT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECC
GDVIEPEDGIVAIGSGSMYALSAARALIRYTDLSAREIVTESLKIAADICIYTNDHIVVE
CCEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEEECCEEEEE
EV
EC
>Mature Secondary Structure
MNRSEKPQLRATTVLGVIRNGKAALGSDGQMTLGNTVIKHSTKKIRRIQHANLITGFAGA
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCC
TADAVTLLDRFDEKLQAFGGQLERSAVELARDWRTDKYLRRLEAMLAVVSADKALIISGT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECC
GDVIEPEDGIVAIGSGSMYALSAARALIRYTDLSAREIVTESLKIAADICIYTNDHIVVE
CCEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEEECCEEEEE
EV
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA