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The map label for this gene is sigW [H]

Identifier: 194333964

GI number: 194333964

Start: 1251054

End: 1251608

Strand: Reverse

Name: sigW [H]

Synonym: Paes_1148

Alternate gene names: 194333964

Gene position: 1251608-1251054 (Counterclockwise)

Preceding gene: 194333969

Following gene: 194333963

Centisome position: 49.81

GC content: 50.09

Gene sequence:

>555_bases
ATGAACCCAATTGATCAGGATATTTCGCAACGCTTCAGGAACGGAGATCCCGACGCTCTTCACGCGGTGGTGACCTGTTG
CCAGAATACCGTTTTCAGGATTGGCCTCAAACTGTTCGCCAATCAGGACGATGCGAAGGATTTCTGTCAGGATGTTTTTC
TGCACGCTTTTGAAAAGAGAGGCCGCTATGATCCGAAACGCCCTTTAGAGCCCTGGTTATACCGCGTGGCTTTAAATTTC
GGTCGAGGAAGGCTGCGCAGAAAACGAAGCTTGTCGTTGATCGATGCCGATGCTTTTCAGCATGTCGATGACAGAGCGGT
TCGGGATCTGGTTGAAGAGGAGAGACGAGTTGCTGTGCAAAAATCTCTCATGCAGCTCAAATCCAACTATCGCGAGTGTT
TACTTTTGCGCTTCGAGTGCGATCTGAAGCTGGAGGAGATAGCCGGGGTTCTGGAGATACCTCTCAGTACGGTGAAAACC
CGGTTGCGCAGGGCAATGGCCGCTTTTAAAGAACGCTATATCGCTGATGGAGGAGACTATGCTGATGAACTGTAA

Upstream 100 bases:

>100_bases
TCTTCTTGGTGCAGGATAGCGGAATGGAATTTTTACAATGACATGCCGGTTTTCTGAAACCTTTTGCCACTCTTATGCAT
AGAAGAGAAAAAAGACGTGC

Downstream 100 bases:

>100_bases
GGATGTAGAACGATATCTCGTTGACCGGGCACTCAAGATTCCTTCAGGCGAGAATCAGGATGCGCTGGAGAAGCATCTGC
AGGCTTGCCCGCATTGCAGG

Product: ECF subfamily RNA polymerase sigma-24 subunit

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNPIDQDISQRFRNGDPDALHAVVTCCQNTVFRIGLKLFANQDDAKDFCQDVFLHAFEKRGRYDPKRPLEPWLYRVALNF
GRGRLRRKRSLSLIDADAFQHVDDRAVRDLVEEERRVAVQKSLMQLKSNYRECLLLRFECDLKLEEIAGVLEIPLSTVKT
RLRRAMAAFKERYIADGGDYADEL

Sequences:

>Translated_184_residues
MNPIDQDISQRFRNGDPDALHAVVTCCQNTVFRIGLKLFANQDDAKDFCQDVFLHAFEKRGRYDPKRPLEPWLYRVALNF
GRGRLRRKRSLSLIDADAFQHVDDRAVRDLVEEERRVAVQKSLMQLKSNYRECLLLRFECDLKLEEIAGVLEIPLSTVKT
RLRRAMAAFKERYIADGGDYADEL
>Mature_184_residues
MNPIDQDISQRFRNGDPDALHAVVTCCQNTVFRIGLKLFANQDDAKDFCQDVFLHAFEKRGRYDPKRPLEPWLYRVALNF
GRGRLRRKRSLSLIDADAFQHVDDRAVRDLVEEERRVAVQKSLMQLKSNYRECLLLRFECDLKLEEIAGVLEIPLSTVKT
RLRRAMAAFKERYIADGGDYADEL

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21436; Mature: 21436

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIDQDISQRFRNGDPDALHAVVTCCQNTVFRIGLKLFANQDDAKDFCQDVFLHAFEKR
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
GRYDPKRPLEPWLYRVALNFGRGRLRRKRSLSLIDADAFQHVDDRAVRDLVEEERRVAVQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSLMQLKSNYRECLLLRFECDLKLEEIAGVLEIPLSTVKTRLRRAMAAFKERYIADGGDY
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
ADEL
CCCC
>Mature Secondary Structure
MNPIDQDISQRFRNGDPDALHAVVTCCQNTVFRIGLKLFANQDDAKDFCQDVFLHAFEKR
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
GRYDPKRPLEPWLYRVALNFGRGRLRRKRSLSLIDADAFQHVDDRAVRDLVEEERRVAVQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSLMQLKSNYRECLLLRFECDLKLEEIAGVLEIPLSTVKTRLRRAMAAFKERYIADGGDY
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
ADEL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]