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The map label for this gene is argB [H]

Identifier: 194333896

GI number: 194333896

Start: 1182782

End: 1183690

Strand: Reverse

Name: argB [H]

Synonym: Paes_1074

Alternate gene names: 194333896

Gene position: 1183690-1182782 (Counterclockwise)

Preceding gene: 194333897

Following gene: 194333895

Centisome position: 47.1

GC content: 50.83

Gene sequence:

>909_bases
ATGAGCAACGTTATGAATGATTTGTGCAGAGACTCTCACCCGGGAATGAAGGAACGCCAGTTAGCGATCGGTCAGGTTCT
CATCGAGGCCCTTCCCTATATCCGTCAGTTTGAAGGCAAAACGTTTGTGATCAAATATGGTGGCGCAGCGATGATAGACG
ATGTATTGAAGAACGCTTTCGCCCAGAACGTGACGCTGCTTCGAAAAGTGGGGATCAATGTCGTCGTTGTTCATGGCGGC
GGCAACGCCATCACCAATACAGCCGACTCAATGGGGCTGCACACCACCTTCGTCCATGGTAAAAGAGTGACCGACCGCAA
GATGATCGATGTCGTTCAGATGACGCTTGCCGGAAAAGTCAATCAGGATATTGTGCGCCTTATCAGCGGGCATGGCGCTA
AAGCTGTCGGCGTCAGCGGTCTGGACGCAAGGACCATTCAGGCGGAGCCTTGCACCGAAGCCGCGCATCTCGGTCTCGTT
GGAGAAGTCGCCTCGGTCAATACCGAATATCTCGACCTGCTCTGCCAGGCAAAGCTCATTCCTGTTATCGCGCCTATTGG
TTTTGACAATGAAGGCAACATCTATAATATCAATGCTGATGATGCGGCAAGCGGTATAGCCATTGCGCTGAAAGCCGAAA
AGCTCATTTATGTCAGCGATGTCGAAGGAGTTCACTGTGGTGACCGAATTCTGAAAAGCGTCTGTAAATCCGAAGCGGCA
GATCTTATCGAACAGGGCATTATTTCCGGAGGGATGATCCCGAAATCACTCTCTGCATACCGTACACTTGATGCCGGTGT
TGGCAAAGTCCATCTCATCGACGGACGATTTGTGCACTCCCTCCTGCTGGAAATCTTTACCAACGCAGGCGTCGGCACAC
AGTTTGTATCTGAAAAAGAGTCTCAATAA

Upstream 100 bases:

>100_bases
AGGCAGCGGCAAGTCTGTCATCTGGACCTGCGATCTCAGCAAAGAGTACGTGGAAATCAACGGAAGTTATAGAACGTGAA
CAAGCAACTACTTATACAAG

Downstream 100 bases:

>100_bases
TCGTAAACATGACATCATCCATGCCCCATCCAACGAAAGAAACAATAGTCAAAAAAAGGGATTTCCTCGGATTTCAGCCT
CTCGATGCAGGAAAGATTAT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSNVMNDLCRDSHPGMKERQLAIGQVLIEALPYIRQFEGKTFVIKYGGAAMIDDVLKNAFAQNVTLLRKVGINVVVVHGG
GNAITNTADSMGLHTTFVHGKRVTDRKMIDVVQMTLAGKVNQDIVRLISGHGAKAVGVSGLDARTIQAEPCTEAAHLGLV
GEVASVNTEYLDLLCQAKLIPVIAPIGFDNEGNIYNINADDAASGIAIALKAEKLIYVSDVEGVHCGDRILKSVCKSEAA
DLIEQGIISGGMIPKSLSAYRTLDAGVGKVHLIDGRFVHSLLLEIFTNAGVGTQFVSEKESQ

Sequences:

>Translated_302_residues
MSNVMNDLCRDSHPGMKERQLAIGQVLIEALPYIRQFEGKTFVIKYGGAAMIDDVLKNAFAQNVTLLRKVGINVVVVHGG
GNAITNTADSMGLHTTFVHGKRVTDRKMIDVVQMTLAGKVNQDIVRLISGHGAKAVGVSGLDARTIQAEPCTEAAHLGLV
GEVASVNTEYLDLLCQAKLIPVIAPIGFDNEGNIYNINADDAASGIAIALKAEKLIYVSDVEGVHCGDRILKSVCKSEAA
DLIEQGIISGGMIPKSLSAYRTLDAGVGKVHLIDGRFVHSLLLEIFTNAGVGTQFVSEKESQ
>Mature_301_residues
SNVMNDLCRDSHPGMKERQLAIGQVLIEALPYIRQFEGKTFVIKYGGAAMIDDVLKNAFAQNVTLLRKVGINVVVVHGGG
NAITNTADSMGLHTTFVHGKRVTDRKMIDVVQMTLAGKVNQDIVRLISGHGAKAVGVSGLDARTIQAEPCTEAAHLGLVG
EVASVNTEYLDLLCQAKLIPVIAPIGFDNEGNIYNINADDAASGIAIALKAEKLIYVSDVEGVHCGDRILKSVCKSEAAD
LIEQGIISGGMIPKSLSAYRTLDAGVGKVHLIDGRFVHSLLLEIFTNAGVGTQFVSEKESQ

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=301, Percent_Identity=27.2425249169435, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693208, Length=227, Percent_Identity=32.5991189427313, Blast_Score=85, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=275, Percent_Identity=26.1818181818182, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 32179; Mature: 32047

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVMNDLCRDSHPGMKERQLAIGQVLIEALPYIRQFEGKTFVIKYGGAAMIDDVLKNAF
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHH
AQNVTLLRKVGINVVVVHGGGNAITNTADSMGLHTTFVHGKRVTDRKMIDVVQMTLAGKV
HHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
NQDIVRLISGHGAKAVGVSGLDARTIQAEPCTEAAHLGLVGEVASVNTEYLDLLCQAKLI
CHHHHHHHHCCCCCEECCCCCCCCEECCCCCCHHHHCCHHHHHHHCCHHHHHHHHHHHHH
PVIAPIGFDNEGNIYNINADDAASGIAIALKAEKLIYVSDVEGVHCGDRILKSVCKSEAA
HEEEECCCCCCCCEEEECCCCCCCCEEEEEEECEEEEEECCCCCCHHHHHHHHHHHHHHH
DLIEQGIISGGMIPKSLSAYRTLDAGVGKVHLIDGRFVHSLLLEIFTNAGVGTQFVSEKE
HHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCC
SQ
CC
>Mature Secondary Structure 
SNVMNDLCRDSHPGMKERQLAIGQVLIEALPYIRQFEGKTFVIKYGGAAMIDDVLKNAF
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHH
AQNVTLLRKVGINVVVVHGGGNAITNTADSMGLHTTFVHGKRVTDRKMIDVVQMTLAGKV
HHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
NQDIVRLISGHGAKAVGVSGLDARTIQAEPCTEAAHLGLVGEVASVNTEYLDLLCQAKLI
CHHHHHHHHCCCCCEECCCCCCCCEECCCCCCHHHHCCHHHHHHHCCHHHHHHHHHHHHH
PVIAPIGFDNEGNIYNINADDAASGIAIALKAEKLIYVSDVEGVHCGDRILKSVCKSEAA
HEEEECCCCCCCCEEEECCCCCCCCEEEEEEECEEEEEECCCCCCHHHHHHHHHHHHHHH
DLIEQGIISGGMIPKSLSAYRTLDAGVGKVHLIDGRFVHSLLLEIFTNAGVGTQFVSEKE
HHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCC
SQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA