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The map label for this gene is 194333892

Identifier: 194333892

GI number: 194333892

Start: 1178653

End: 1179687

Strand: Reverse

Name: 194333892

Synonym: Paes_1070

Alternate gene names: NA

Gene position: 1179687-1178653 (Counterclockwise)

Preceding gene: 194333893

Following gene: 194333891

Centisome position: 46.94

GC content: 58.74

Gene sequence:

>1035_bases
ATGGGGGAACAGATGGATAGTCAGACACTCAGTTCTGTAGCAAAAGCCATCGTGGCGCCAGGGAAAGGCGTGCTGGCGGC
AGACGAAAGCACTCCCACGATCAGGAAGCGTTTCGATTCCATCCAGGTCGAATCCACCGAGGAAAACCGTCAACAATACC
GGGAAATCCTTTTTACAGCACAAAACATCGAACGATCTATCGGCGGGGTCATTCTTTTCGATGAAACATTGCGCCAGTCT
GCAAAGGACGGCACACCCTTCCCGACTCTCCTTTCCAAACGGGGTATCGTACCGGGTATCAAGGTCGATAAAGGCGCCAA
GGCGCTCGCGCTCTATGCCGGCGAAAAGATTACTGAAGGCCTCGACGGCCTGCGTGAACGATTGCTGGAGTATAAAGAAC
TTGGCGCACAGTTCGCGAAGTGGCGGGCGGTTATCGGGATCGACGAGCGAGACATCCCTTCCCCCTTCGGCATCCGCGCG
AACGCTCATGCATTGGCGCGTTACGCGGCACTCTGTCAGGAGCTGGATATCGTCCCGATCGTCGAGCCGGAGGTCCTCAT
GGACGGCAGCCACGACATCGAACGTTGCGAAGTCGTGACGTCGCAGGTGCTCGAAGCGGTTTTCGCCGAACTCGACGCCC
ATCATGTCCTGTTCGAAGGCATGCTGCTGAAGCCGAACATGGTGATTGCCGGCATGCAATGCTCCCGTCAGGCGGGCGTC
GAGGAGGTCGCTGAGGCAACGATGCGCTGCATGACCCGTTACGTGCCGGCGGCTGTTCCGGGGATCGTCTTTCTGTCGGG
AGGGCAAAGTGCAGAAAAGGCCACGGCCCACCTGAACGCCATGAACGCGACGGGCCCGTATCCGTGGGAGGTCAGCTTCT
CCTACGGACGTGCGCTGCAGGCGCCGGTGCTTGCAGCCTGGAAGGGAGAGGAGAACAATGCTTTCGCCGCACAACATGCA
TTATCAAAGCGATGCCGCCTCAATGGCCTGGCCCGCGACGGAGCGTATGCACAGGAGATGGAGCAGGAAGCGTAA

Upstream 100 bases:

>100_bases
ACGGAACTGTCCCGCACCATGTGTTTGGGTGGATGAGATAGATGGGTCATGACGTTATGACCGATAAGATTGTAAATAGA
CGAAGCAACAAAACGAAAGG

Downstream 100 bases:

>100_bases
CCGGGTGGGGGCGTCGTCGGCCCCCAACACGGACAGTCGGGACACGGAAAAAATCAAACAGAGCAGAAGATGGAAACACT
ACAATCCGGTCATGAAGAAC

Product: Fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGEQMDSQTLSSVAKAIVAPGKGVLAADESTPTIRKRFDSIQVESTEENRQQYREILFTAQNIERSIGGVILFDETLRQS
AKDGTPFPTLLSKRGIVPGIKVDKGAKALALYAGEKITEGLDGLRERLLEYKELGAQFAKWRAVIGIDERDIPSPFGIRA
NAHALARYAALCQELDIVPIVEPEVLMDGSHDIERCEVVTSQVLEAVFAELDAHHVLFEGMLLKPNMVIAGMQCSRQAGV
EEVAEATMRCMTRYVPAAVPGIVFLSGGQSAEKATAHLNAMNATGPYPWEVSFSYGRALQAPVLAAWKGEENNAFAAQHA
LSKRCRLNGLARDGAYAQEMEQEA

Sequences:

>Translated_344_residues
MGEQMDSQTLSSVAKAIVAPGKGVLAADESTPTIRKRFDSIQVESTEENRQQYREILFTAQNIERSIGGVILFDETLRQS
AKDGTPFPTLLSKRGIVPGIKVDKGAKALALYAGEKITEGLDGLRERLLEYKELGAQFAKWRAVIGIDERDIPSPFGIRA
NAHALARYAALCQELDIVPIVEPEVLMDGSHDIERCEVVTSQVLEAVFAELDAHHVLFEGMLLKPNMVIAGMQCSRQAGV
EEVAEATMRCMTRYVPAAVPGIVFLSGGQSAEKATAHLNAMNATGPYPWEVSFSYGRALQAPVLAAWKGEENNAFAAQHA
LSKRCRLNGLARDGAYAQEMEQEA
>Mature_343_residues
GEQMDSQTLSSVAKAIVAPGKGVLAADESTPTIRKRFDSIQVESTEENRQQYREILFTAQNIERSIGGVILFDETLRQSA
KDGTPFPTLLSKRGIVPGIKVDKGAKALALYAGEKITEGLDGLRERLLEYKELGAQFAKWRAVIGIDERDIPSPFGIRAN
AHALARYAALCQELDIVPIVEPEVLMDGSHDIERCEVVTSQVLEAVFAELDAHHVLFEGMLLKPNMVIAGMQCSRQAGVE
EVAEATMRCMTRYVPAAVPGIVFLSGGQSAEKATAHLNAMNATGPYPWEVSFSYGRALQAPVLAAWKGEENNAFAAQHAL
SKRCRLNGLARDGAYAQEMEQEA

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI4885063, Length=329, Percent_Identity=54.7112462006079, Blast_Score=350, Evalue=1e-96,
Organism=Homo sapiens, GI34577112, Length=330, Percent_Identity=55.1515151515151, Blast_Score=345, Evalue=3e-95,
Organism=Homo sapiens, GI34577110, Length=330, Percent_Identity=55.1515151515151, Blast_Score=345, Evalue=3e-95,
Organism=Homo sapiens, GI4557305, Length=330, Percent_Identity=55.1515151515151, Blast_Score=345, Evalue=3e-95,
Organism=Homo sapiens, GI193794814, Length=330, Percent_Identity=55.1515151515151, Blast_Score=345, Evalue=3e-95,
Organism=Homo sapiens, GI40354205, Length=335, Percent_Identity=53.7313432835821, Blast_Score=343, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI71983985, Length=334, Percent_Identity=52.3952095808383, Blast_Score=330, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI25150450, Length=330, Percent_Identity=51.2121212121212, Blast_Score=327, Evalue=8e-90,
Organism=Caenorhabditis elegans, GI71983990, Length=240, Percent_Identity=51.25, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24650282, Length=330, Percent_Identity=53.9393939393939, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24650280, Length=330, Percent_Identity=53.9393939393939, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24650278, Length=330, Percent_Identity=53.9393939393939, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI221459619, Length=330, Percent_Identity=53.9393939393939, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI24650288, Length=330, Percent_Identity=53.9393939393939, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI45553577, Length=330, Percent_Identity=53.6363636363636, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24650304, Length=330, Percent_Identity=47.2727272727273, Blast_Score=301, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37476; Mature: 37345

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00158 ALDOLASE_CLASS_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEQMDSQTLSSVAKAIVAPGKGVLAADESTPTIRKRFDSIQVESTEENRQQYREILFTA
CCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHH
QNIERSIGGVILFDETLRQSAKDGTPFPTLLSKRGIVPGIKVDKGAKALALYAGEKITEG
HHHHHHHCCEEEECHHHHHHCCCCCCCHHHHHCCCCCCCCEECCCCCEEEECCCHHHHHH
LDGLRERLLEYKELGAQFAKWRAVIGIDERDIPSPFGIRANAHALARYAALCQELDIVPI
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
VEPEVLMDGSHDIERCEVVTSQVLEAVFAELDAHHVLFEGMLLKPNMVIAGMQCSRQAGV
CCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEEECCHHHHHCCH
EEVAEATMRCMTRYVPAAVPGIVFLSGGQSAEKATAHLNAMNATGPYPWEVSFSYGRALQ
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHC
APVLAAWKGEENNAFAAQHALSKRCRLNGLARDGAYAQEMEQEA
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
GEQMDSQTLSSVAKAIVAPGKGVLAADESTPTIRKRFDSIQVESTEENRQQYREILFTA
CCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHH
QNIERSIGGVILFDETLRQSAKDGTPFPTLLSKRGIVPGIKVDKGAKALALYAGEKITEG
HHHHHHHCCEEEECHHHHHHCCCCCCCHHHHHCCCCCCCCEECCCCCEEEECCCHHHHHH
LDGLRERLLEYKELGAQFAKWRAVIGIDERDIPSPFGIRANAHALARYAALCQELDIVPI
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
VEPEVLMDGSHDIERCEVVTSQVLEAVFAELDAHHVLFEGMLLKPNMVIAGMQCSRQAGV
CCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEEECCHHHHHCCH
EEVAEATMRCMTRYVPAAVPGIVFLSGGQSAEKATAHLNAMNATGPYPWEVSFSYGRALQ
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHC
APVLAAWKGEENNAFAAQHALSKRCRLNGLARDGAYAQEMEQEA
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]