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The map label for this gene is wecB [H]

Identifier: 193214509

GI number: 193214509

Start: 945519

End: 946622

Strand: Direct

Name: wecB [H]

Synonym: Ctha_0793

Alternate gene names: 193214509

Gene position: 945519-946622 (Clockwise)

Preceding gene: 193214504

Following gene: 193214510

Centisome position: 28.71

GC content: 48.19

Gene sequence:

>1104_bases
TTGAAGAAGATAATTTCGGTTGTTGGCGCAAGACCCAACTTTATGAAAATTGCCCCGCTCCACCACGCACTTAAAAAATC
GGGAAAATATCAATCCATTATCCTACACACCGGGCAGCATTACGACGAAAAAATGTCGAAGGTGTTTTTTGACGATTTAG
GATTGCCCGAACCCGATATTTACTTGGGAATTGGCTCCGGCTCTCACGCCGAACAAACCGCGAAAGTGATGATTGAGTTT
GAAAAAGTGCTCATGAAAGAGCTGCCGGAAATAGTGATTGTGGTTGGCGATGTGAATTCCACGCTGGCCTGCTCGATTGT
GGCCGCCAAGTTGCTTGTGCCGGTGGCGCATGTGGAAGCCGGCCTCAGAAGCGGCGACCGCACCATGCCAGAGGAAATCA
ACCGAATTGTAACCGATTCGATTTCCGATCTGCTTTTTGTGAGCGAGCCCAGCGGCATGCACAACCTGATAAACGAAGGT
GTTTCGGAAGAAAAAATGTTTTTCGTCGGAAATATCATGATCGATAGCCTTGTTGCCCATGTGCAAAAAGCCAATCAATC
GAATGTGCTGAAAAATCTCGGCCTCGAGGAAAAATCTTACACGCTCGTTACGCTGCATCGCCCGAGCAATGTCGATAGCA
AAGAAAGCCTTGAAAAAATGCTGCGGATTTTTGCAGAAATTGCGCATCGCTCGCAAATCGTTTTCCCAATTCATCCGCGC
ACACGCAAGCGCTTGGAAGATTTTGGCTTAATGGAAAAAGCCAATGCCATTTCCAAACTTCGGCTGATCGAACCGCAAGG
CTACATTGAATTCCTGAAATTGATGAAAGAAGCCGCGCTCGTGCTCACCGATTCCGGCGGCATTCAGGAAGAAACAACTG
TGCTTGGCGTGCAATGCCTCACCATGCGCGAAAATACCGAGCGCCCGGCCACCATCGAAGTTGGGACCAACCAGCTTGTC
GGCACCGATGAAAGCGAAATCAAAGCCAAAGCGATGGAAGTTTTAAACGGCAATATCAAAGAAGGAAAAATCCCAGAAAA
ATGGGACGGAAGAACCGCCGATCGCATTGTTGCCACATTGGACCACATTTTTGCAACCTGGTAA

Upstream 100 bases:

>100_bases
GGATTTTCAAAGTGGAAACAATTGCGAAAAAACGCGATATTTGGCCAACCGGTGTTCCATCAATGCTCATCAAACTGTTT
AAAAGAAAGGAATATAAGCC

Downstream 100 bases:

>100_bases
AAAAAGCTTTGCATCCAAAAAAGAGGAGCGAGTCTGAAAGCTCGCTCCTGCATTTTTATATTTCCTCTGAACGATTTATG
TATTTCCCTAACGGCTCTTT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKKIISVVGARPNFMKIAPLHHALKKSGKYQSIILHTGQHYDEKMSKVFFDDLGLPEPDIYLGIGSGSHAEQTAKVMIEF
EKVLMKELPEIVIVVGDVNSTLACSIVAAKLLVPVAHVEAGLRSGDRTMPEEINRIVTDSISDLLFVSEPSGMHNLINEG
VSEEKMFFVGNIMIDSLVAHVQKANQSNVLKNLGLEEKSYTLVTLHRPSNVDSKESLEKMLRIFAEIAHRSQIVFPIHPR
TRKRLEDFGLMEKANAISKLRLIEPQGYIEFLKLMKEAALVLTDSGGIQEETTVLGVQCLTMRENTERPATIEVGTNQLV
GTDESEIKAKAMEVLNGNIKEGKIPEKWDGRTADRIVATLDHIFATW

Sequences:

>Translated_367_residues
MKKIISVVGARPNFMKIAPLHHALKKSGKYQSIILHTGQHYDEKMSKVFFDDLGLPEPDIYLGIGSGSHAEQTAKVMIEF
EKVLMKELPEIVIVVGDVNSTLACSIVAAKLLVPVAHVEAGLRSGDRTMPEEINRIVTDSISDLLFVSEPSGMHNLINEG
VSEEKMFFVGNIMIDSLVAHVQKANQSNVLKNLGLEEKSYTLVTLHRPSNVDSKESLEKMLRIFAEIAHRSQIVFPIHPR
TRKRLEDFGLMEKANAISKLRLIEPQGYIEFLKLMKEAALVLTDSGGIQEETTVLGVQCLTMRENTERPATIEVGTNQLV
GTDESEIKAKAMEVLNGNIKEGKIPEKWDGRTADRIVATLDHIFATW
>Mature_367_residues
MKKIISVVGARPNFMKIAPLHHALKKSGKYQSIILHTGQHYDEKMSKVFFDDLGLPEPDIYLGIGSGSHAEQTAKVMIEF
EKVLMKELPEIVIVVGDVNSTLACSIVAAKLLVPVAHVEAGLRSGDRTMPEEINRIVTDSISDLLFVSEPSGMHNLINEG
VSEEKMFFVGNIMIDSLVAHVQKANQSNVLKNLGLEEKSYTLVTLHRPSNVDSKESLEKMLRIFAEIAHRSQIVFPIHPR
TRKRLEDFGLMEKANAISKLRLIEPQGYIEFLKLMKEAALVLTDSGGIQEETTVLGVQCLTMRENTERPATIEVGTNQLV
GTDESEIKAKAMEVLNGNIKEGKIPEKWDGRTADRIVATLDHIFATW

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=349, Percent_Identity=35.243553008596, Blast_Score=165, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40819; Mature: 40819

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIISVVGARPNFMKIAPLHHALKKSGKYQSIILHTGQHYDEKMSKVFFDDLGLPEPDI
CHHHHHHHCCCCCCEEEHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCE
YLGIGSGSHAEQTAKVMIEFEKVLMKELPEIVIVVGDVNSTLACSIVAAKLLVPVAHVEA
EEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
GLRSGDRTMPEEINRIVTDSISDLLFVSEPSGMHNLINEGVSEEKMFFVGNIMIDSLVAH
HHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCCCCEEEHHHHHHHHHHHH
VQKANQSNVLKNLGLEEKSYTLVTLHRPSNVDSKESLEKMLRIFAEIAHRSQIVFPIHPR
HHHCCHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCH
TRKRLEDFGLMEKANAISKLRLIEPQGYIEFLKLMKEAALVLTDSGGIQEETTVLGVQCL
HHHHHHHCCHHHHHHHHHHEEEECCCCHHHHHHHHHHHHEEEECCCCCCCHHEEEEEEEE
TMRENTERPATIEVGTNQLVGTDESEIKAKAMEVLNGNIKEGKIPEKWDGRTADRIVATL
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
DHIFATW
HHHHHCC
>Mature Secondary Structure
MKKIISVVGARPNFMKIAPLHHALKKSGKYQSIILHTGQHYDEKMSKVFFDDLGLPEPDI
CHHHHHHHCCCCCCEEEHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCE
YLGIGSGSHAEQTAKVMIEFEKVLMKELPEIVIVVGDVNSTLACSIVAAKLLVPVAHVEA
EEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
GLRSGDRTMPEEINRIVTDSISDLLFVSEPSGMHNLINEGVSEEKMFFVGNIMIDSLVAH
HHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCCCCEEEHHHHHHHHHHHH
VQKANQSNVLKNLGLEEKSYTLVTLHRPSNVDSKESLEKMLRIFAEIAHRSQIVFPIHPR
HHHCCHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCH
TRKRLEDFGLMEKANAISKLRLIEPQGYIEFLKLMKEAALVLTDSGGIQEETTVLGVQCL
HHHHHHHCCHHHHHHHHHHEEEECCCCHHHHHHHHHHHHEEEECCCCCCCHHEEEEEEEE
TMRENTERPATIEVGTNQLVGTDESEIKAKAMEVLNGNIKEGKIPEKWDGRTADRIVATL
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
DHIFATW
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]