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The map label for this gene is lpxA [H]

Identifier: 193214492

GI number: 193214492

Start: 923722

End: 924528

Strand: Direct

Name: lpxA [H]

Synonym: Ctha_0776

Alternate gene names: 193214492

Gene position: 923722-924528 (Clockwise)

Preceding gene: 193214491

Following gene: 193214493

Centisome position: 28.05

GC content: 49.81

Gene sequence:

>807_bases
ATGAGTACCATTTCAGAAACAAAGATTCATCCATTAGCCAGCGTAAGTTCAACTGCTAAAATCGGAAACGGCGTAAAAAT
ACACCCGTTTGCGGTTATCGAAGACGATGTAGAAATTGATGACGGCGCGATTATCGACCCGCACGCGGTGCTGCTGAGCG
GCGTGCGAATTGGCAAAGATTGCCACATTCACTCCGGCGCGGTGCTTGGTGCAAAGCCGCAAGATTTGAAATTTCGCGGC
GAAAAAACTTATGTATTTATCGGCGACCGCAGCGTTATTCGCGAGTGCGTCACCATTAATGTTGGCACAAAAGCCTCCGG
CCAAACCATCATCGGTTCGGATTGTTTGCTCATGGCCTATGTTCATGTCGGACATGATTGCATCATCGGCAACCATGTGA
TTATCGCCAACACGGTTCAATTTGGCGGCCATTGCGAGGTGGGCGATTATGTCGTGATTGGTGGCATGACGGGCTTGCAC
CAGTTCGTGCGCGTCGGTCGGCATGTGATGCTCGGCGCCATGACGAAAAATGTGCATGACATTCCGCCGTATGTGACGAC
ATCGCACGACCGCTACGAAGGCGTCAATGTCATTGGGCTGAAACGGCGCGGCTATTCCTCCGAAACGATTTCGCACATCC
GTGACGTGTATCGCGTGATTTTCCAATCGGGCTTGCTTATTAAAAACGCTGTCGAAAAAGTTAAAGCCGAATTTCCGAAA
ACGCCTGAAGTGGAAGAAATTCTCGCCTTCTTTGAAGCCGAAAGCAAACGAAAATACATCCGGCCATATATGGTGGGAAA
AGCCTAA

Upstream 100 bases:

>100_bases
AGCTTAATGAGATTCGACGCACTTTGGGAAGAAACACAACCGGAAATGACGCCAGTGCATCGGAGAGCTCACTTGATTCG
ATCGAAAAAACTTTACAGCC

Downstream 100 bases:

>100_bases
TTTTTCATTTTAGTTAATAGAGACGCGAATTTTTGCGTCTCTATTTGTTTACGTTCGGCCTTTAATTGAGATTTTGTCGA
GCCGTTTTAGGCGAAGCATC

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSTISETKIHPLASVSSTAKIGNGVKIHPFAVIEDDVEIDDGAIIDPHAVLLSGVRIGKDCHIHSGAVLGAKPQDLKFRG
EKTYVFIGDRSVIRECVTINVGTKASGQTIIGSDCLLMAYVHVGHDCIIGNHVIIANTVQFGGHCEVGDYVVIGGMTGLH
QFVRVGRHVMLGAMTKNVHDIPPYVTTSHDRYEGVNVIGLKRRGYSSETISHIRDVYRVIFQSGLLIKNAVEKVKAEFPK
TPEVEEILAFFEAESKRKYIRPYMVGKA

Sequences:

>Translated_268_residues
MSTISETKIHPLASVSSTAKIGNGVKIHPFAVIEDDVEIDDGAIIDPHAVLLSGVRIGKDCHIHSGAVLGAKPQDLKFRG
EKTYVFIGDRSVIRECVTINVGTKASGQTIIGSDCLLMAYVHVGHDCIIGNHVIIANTVQFGGHCEVGDYVVIGGMTGLH
QFVRVGRHVMLGAMTKNVHDIPPYVTTSHDRYEGVNVIGLKRRGYSSETISHIRDVYRVIFQSGLLIKNAVEKVKAEFPK
TPEVEEILAFFEAESKRKYIRPYMVGKA
>Mature_267_residues
STISETKIHPLASVSSTAKIGNGVKIHPFAVIEDDVEIDDGAIIDPHAVLLSGVRIGKDCHIHSGAVLGAKPQDLKFRGE
KTYVFIGDRSVIRECVTINVGTKASGQTIIGSDCLLMAYVHVGHDCIIGNHVIIANTVQFGGHCEVGDYVVIGGMTGLHQ
FVRVGRHVMLGAMTKNVHDIPPYVTTSHDRYEGVNVIGLKRRGYSSETISHIRDVYRVIFQSGLLIKNAVEKVKAEFPKT
PEVEEILAFFEAESKRKYIRPYMVGKA

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=257, Percent_Identity=44.3579766536965, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1786376, Length=192, Percent_Identity=30.2083333333333, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 29304; Mature: 29173

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTISETKIHPLASVSSTAKIGNGVKIHPFAVIEDDVEIDDGAIIDPHAVLLSGVRIGKD
CCCCCCCCCCCHHHCCCHHHCCCCEEEEEEEEEECCCCCCCCCEECHHHHHHHCCEECCC
CHIHSGAVLGAKPQDLKFRGEKTYVFIGDRSVIRECVTINVGTKASGQTIIGSDCLLMAY
CEEECCEEECCCCCCCEEECCEEEEEECCHHHHHHHHEEECCCCCCCCEEECCCHHHHHH
VHVGHDCIIGNHVIIANTVQFGGHCEVGDYVVIGGMTGLHQFVRVGRHVMLGAMTKNVHD
HHCCCEEEECCEEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHEEHHHHCCCCC
IPPYVTTSHDRYEGVNVIGLKRRGYSSETISHIRDVYRVIFQSGLLIKNAVEKVKAEFPK
CCCCEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
TPEVEEILAFFEAESKRKYIRPYMVGKA
CCCHHHHHHHHHHHCCHHHCCCEECCCC
>Mature Secondary Structure 
STISETKIHPLASVSSTAKIGNGVKIHPFAVIEDDVEIDDGAIIDPHAVLLSGVRIGKD
CCCCCCCCCCHHHCCCHHHCCCCEEEEEEEEEECCCCCCCCCEECHHHHHHHCCEECCC
CHIHSGAVLGAKPQDLKFRGEKTYVFIGDRSVIRECVTINVGTKASGQTIIGSDCLLMAY
CEEECCEEECCCCCCCEEECCEEEEEECCHHHHHHHHEEECCCCCCCCEEECCCHHHHHH
VHVGHDCIIGNHVIIANTVQFGGHCEVGDYVVIGGMTGLHQFVRVGRHVMLGAMTKNVHD
HHCCCEEEECCEEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHEEHHHHCCCCC
IPPYVTTSHDRYEGVNVIGLKRRGYSSETISHIRDVYRVIFQSGLLIKNAVEKVKAEFPK
CCCCEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
TPEVEEILAFFEAESKRKYIRPYMVGKA
CCCHHHHHHHHHHHCCHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA