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The map label for this gene is ileS [H]

Identifier: 193214471

GI number: 193214471

Start: 886016

End: 889252

Strand: Direct

Name: ileS [H]

Synonym: Ctha_0754

Alternate gene names: 193214471

Gene position: 886016-889252 (Clockwise)

Preceding gene: 193214470

Following gene: 193214472

Centisome position: 26.9

GC content: 46.65

Gene sequence:

>3237_bases
ATGGCAAAATTTAAAGAACTTCCCGCAGAACTTAGTTATAGCGCTTTGGAAGCGGAGGTTTTAGCGTTTTGGAAGAAAAA
CAATATTTTTGAGAAAAGCATCGCGTCACGCGCGGAAGGCAAAGCATTCACCTTTTACGACGGCCCTCCAACCGTCAATG
GAAAACCTGGTGTACACCACGTTTTTAGCCGCACGATCAAAGACCTTATCTGCCGTTACAGGACCATGAAAGGGTTTTCG
GTTCGCCGAAAAGCAGGTTGGGATACACACGGCTTACCCGTTGAAATTTCCGTCGAGCAAAAATTAGGGCTGAAAAATAA
ATCTCAGGTCGAAGGCTTCGGCACGGATGAGTTCAACCGCGAAGCAAAAGCGCTGGTTTATCACCATATCAACGATAGCA
AAGAAGGCTGGGGCAAACTGACCGAGCTGATGGGCTATTGGGTCGATATGGACTCGCCTTACATTACTTGTACAAATGAA
TATATAGAGTCGGTTTGGTGGGGACTGAAACAAATTTTTGACAAAGGCCTCATTTATAAAGATTATAAAATCGTCCCGCA
AGACCCGAAATCGGAAACCGTTCTAAGCTCGCATGAGCTGGCTTTAGGCTATCGGGAAATTAAAGACCCCAGCGTTTACG
TCAAATTTAAGTTAAAAGACTCGGACGAATCGTTCTTGGTTTGGACGACCACGCCTTGGACATTGATCTCTAACGTCGCG
CTTTGTGTCGGCCCGGATGTCGAATATGTGAAGGTTCGCACGGAGGAACATGGCGTTTTAATTCTTGCTAAATCAAGGAT
CTCCGTTCTCGGCAAAAACGAAGACGGCAACACTTGGGAAATTTTGGAAACGTGCACGGGCGAAGATCTTGAAGGCATCG
AGTATGAGCCACTTTTCTCTTATGTTCCTGTTAAGAAAAAAGCTTTTTTCGTAACGCTCGGCGATTTCGTTTCGACCGAA
GATGGTAGCGGCATCGTGCATATTGCGCCGGCGTTTGGCGCGGACGACTACGAGTTGCTGAAAAAATACGACCTGCCCAT
GCTTCAGCCCGTCGCAAGAAACGGCTGTTTTACGGCGGAGGTCTCCGATTACGAAGGCGTGTTTTTCAAAGATGCCGACA
AAGACATCATTCTCGCTTTAAAAAATAAAGGCAAGCTTTTCAAAAAAGAAACTGTCACGCACAGTTATCCTTTCTCTTGG
CGCTACAATGTACCGGTGCTTTATTACGCTCGCGAATCGTGGTACATCAGAACCACCGATGTTGCAAAGCGCATGATGGC
TATTAATAAAGAAATCAATTGGTGCCCGCCAGAAATCGGATCGGGGCGTTTTGGAAATTGGCTGGAAGAAAATAAAGACT
GGGCGATTTCGCGCGAACGATTCTGGGGAACACCGCTACCGGTTTGGGTTTCCGAAGATTTCCAAATCGGTGATGACCAC
ACCAGCGGCAAAATGTTCGCCGTCAGTTCGATCGCAGAGCTAAAAGAAGGCTTTATCGATATCGAAGGCAAGCAAATGAA
ACTCAGCGATGCACTTGAGCAGAAATTTGTTGAGCTGGATTTGCACAAGCCGTTTGTTGATAGCGTTTATTTTATCAAAG
ATGGAAAAACTTTCCGCCGCACACCCGAGCTCATCGACGTTTGGTTTGATAGCGGCGCAATGCCATTTGCCCAACTTCAT
TATCCGTTCGAAAACAAAAAGCTTTTTGAAAACGGCGGCTTTCCTGCCGACTTCATCGCGGAAGGCGTCGACCAAACGCG
CGGCTGGTTCTACACGCTTCACGCCATTGGCACGCTGATTTTCAACAAACCGGCTTATAAAAATCTCATCGTTAATGGCC
ACATTTTGGATAAAGACGGACAAAAAATGTCCAAATCGAAGGGCAATGTGGTCGATCCGTTTGAGATGATGAGCAAATAC
GGCGCAGATTCCTTGCGCTGGTATTTGATTTCAACCAGCCCACCTTGGCGCCCGAAATCGTTTAACCCGGAAGAATTGCT
CGAAGGCCAACGGAAGTTTTTCCGAGCGCTCGTCAACAGCTACAACTTTTTCGTGCTTTACGCCAATGTCGACGAGTTTG
ATTATTCCGAAAACAATTTGCCTGTCTGCGAACGCAGCGAACTTGATAGATGGATTATCTCGGCGCTCAATACGCTTGTT
AAGCATGTTGAAGCAGCAATGGAAAATTATGACCCGACGGCTGCCGCAAGACACATCGAGGCCTTTACGGTAGATGATCT
TTCGAATTGGTACATTCGCCGGTCGCGACGCCGTTTTTGGAAGGGTGAAAATAACAACGATAAACTTGCAGCCTATCAAA
CGCTGTATCAGTGTTTGTTGGTTGTTAGCAAGCTTGTTGCGCCAGTCTCACCGTTTATCAGCGATTGGATTTATCGAAAT
CTGAACGAAGTGTCAGGCAAGGAAAGTTTCGAGTCCGTACACTTGGCCTATTTTCCATCGGTGGAAGAAACGGCGATCGA
TTCGGATCTCGAGCTGCGAATGAAAAAAGCACAAATCATCAGTTCTTTGGTTCGAACCATGCGCGAAAAATCGGGAATTA
AAGTTCGCCAACCACTCAAGCGCGTGCTGCTGCCTATTTCTGATCCGCGCGAGCGCCGCGAAATCGAAAAGATTCGGACG
ATCGTTCTCGATGAGGTGAATGTTCATAGTCTTGAGTATGTCGACGACGATTCCGGCGTGGTCAATAAAAAGGCCAAACC
GAATTTTAAAGTGCTTGGGCCGAAATTTGGGAAAGACGCCAAAGCCGTTGCCGCGTGCATTCGCGAGTTGCCGTCAAGCC
AAGTGGCGAAGTTAGAGCGAAACGGAATACTGGCAATAGACGTTCAAGGGAAAAGCGCTGAAATCACTCTCGAAGACATC
GAGATTTTGCATGAAGATATTGAGGGCTGGTTGGTTGCTTACGATAGCACCTACAAACTGATGGTCGCTCTCGACACAGA
AATTGACGAAACGCTTCGCGCAGAAGGGCTTGCGCGTGAGCTCGTTAGCCGAATTCAATCTTTACGAAAAGACAAAGGAC
TTGAAATCACCGATAGAATCAAACTCTACTTAGATCCGTCGGAGTTGCTAAAAATTTCCATAGAGCAAAATTTGGAGTAC
ATCAAAGCCGAAACGCTTGCAACCGATATTGATTTCAACCTGGATGGAATGCAATCGGTGGCAAAAACGGAAGACATTAA
CGGCGAAATTTGCAGAATGGCATTGGAGAAAAAATAG

Upstream 100 bases:

>100_bases
CCTAACCGTCGGGTTCAAAAGCTTTGTGAATTGACCTGTAAATCTTATATTGCCGGCCTTTTTAGGGGTGTAGTAGGAGG
TAAAAGACTAAAGAAACGGC

Downstream 100 bases:

>100_bases
CACCACTTCCGGCAGAAACTTTAAAACTTAAGTATCATGCCAAGAAAAACAGCATCATCTGTATCAGCCAAACCGGCTTC
TGAAAAAATTGAAGTGGTGT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1078; Mature: 1077

Protein sequence:

>1078_residues
MAKFKELPAELSYSALEAEVLAFWKKNNIFEKSIASRAEGKAFTFYDGPPTVNGKPGVHHVFSRTIKDLICRYRTMKGFS
VRRKAGWDTHGLPVEISVEQKLGLKNKSQVEGFGTDEFNREAKALVYHHINDSKEGWGKLTELMGYWVDMDSPYITCTNE
YIESVWWGLKQIFDKGLIYKDYKIVPQDPKSETVLSSHELALGYREIKDPSVYVKFKLKDSDESFLVWTTTPWTLISNVA
LCVGPDVEYVKVRTEEHGVLILAKSRISVLGKNEDGNTWEILETCTGEDLEGIEYEPLFSYVPVKKKAFFVTLGDFVSTE
DGSGIVHIAPAFGADDYELLKKYDLPMLQPVARNGCFTAEVSDYEGVFFKDADKDIILALKNKGKLFKKETVTHSYPFSW
RYNVPVLYYARESWYIRTTDVAKRMMAINKEINWCPPEIGSGRFGNWLEENKDWAISRERFWGTPLPVWVSEDFQIGDDH
TSGKMFAVSSIAELKEGFIDIEGKQMKLSDALEQKFVELDLHKPFVDSVYFIKDGKTFRRTPELIDVWFDSGAMPFAQLH
YPFENKKLFENGGFPADFIAEGVDQTRGWFYTLHAIGTLIFNKPAYKNLIVNGHILDKDGQKMSKSKGNVVDPFEMMSKY
GADSLRWYLISTSPPWRPKSFNPEELLEGQRKFFRALVNSYNFFVLYANVDEFDYSENNLPVCERSELDRWIISALNTLV
KHVEAAMENYDPTAAARHIEAFTVDDLSNWYIRRSRRRFWKGENNNDKLAAYQTLYQCLLVVSKLVAPVSPFISDWIYRN
LNEVSGKESFESVHLAYFPSVEETAIDSDLELRMKKAQIISSLVRTMREKSGIKVRQPLKRVLLPISDPRERREIEKIRT
IVLDEVNVHSLEYVDDDSGVVNKKAKPNFKVLGPKFGKDAKAVAACIRELPSSQVAKLERNGILAIDVQGKSAEITLEDI
EILHEDIEGWLVAYDSTYKLMVALDTEIDETLRAEGLARELVSRIQSLRKDKGLEITDRIKLYLDPSELLKISIEQNLEY
IKAETLATDIDFNLDGMQSVAKTEDINGEICRMALEKK

Sequences:

>Translated_1078_residues
MAKFKELPAELSYSALEAEVLAFWKKNNIFEKSIASRAEGKAFTFYDGPPTVNGKPGVHHVFSRTIKDLICRYRTMKGFS
VRRKAGWDTHGLPVEISVEQKLGLKNKSQVEGFGTDEFNREAKALVYHHINDSKEGWGKLTELMGYWVDMDSPYITCTNE
YIESVWWGLKQIFDKGLIYKDYKIVPQDPKSETVLSSHELALGYREIKDPSVYVKFKLKDSDESFLVWTTTPWTLISNVA
LCVGPDVEYVKVRTEEHGVLILAKSRISVLGKNEDGNTWEILETCTGEDLEGIEYEPLFSYVPVKKKAFFVTLGDFVSTE
DGSGIVHIAPAFGADDYELLKKYDLPMLQPVARNGCFTAEVSDYEGVFFKDADKDIILALKNKGKLFKKETVTHSYPFSW
RYNVPVLYYARESWYIRTTDVAKRMMAINKEINWCPPEIGSGRFGNWLEENKDWAISRERFWGTPLPVWVSEDFQIGDDH
TSGKMFAVSSIAELKEGFIDIEGKQMKLSDALEQKFVELDLHKPFVDSVYFIKDGKTFRRTPELIDVWFDSGAMPFAQLH
YPFENKKLFENGGFPADFIAEGVDQTRGWFYTLHAIGTLIFNKPAYKNLIVNGHILDKDGQKMSKSKGNVVDPFEMMSKY
GADSLRWYLISTSPPWRPKSFNPEELLEGQRKFFRALVNSYNFFVLYANVDEFDYSENNLPVCERSELDRWIISALNTLV
KHVEAAMENYDPTAAARHIEAFTVDDLSNWYIRRSRRRFWKGENNNDKLAAYQTLYQCLLVVSKLVAPVSPFISDWIYRN
LNEVSGKESFESVHLAYFPSVEETAIDSDLELRMKKAQIISSLVRTMREKSGIKVRQPLKRVLLPISDPRERREIEKIRT
IVLDEVNVHSLEYVDDDSGVVNKKAKPNFKVLGPKFGKDAKAVAACIRELPSSQVAKLERNGILAIDVQGKSAEITLEDI
EILHEDIEGWLVAYDSTYKLMVALDTEIDETLRAEGLARELVSRIQSLRKDKGLEITDRIKLYLDPSELLKISIEQNLEY
IKAETLATDIDFNLDGMQSVAKTEDINGEICRMALEKK
>Mature_1077_residues
AKFKELPAELSYSALEAEVLAFWKKNNIFEKSIASRAEGKAFTFYDGPPTVNGKPGVHHVFSRTIKDLICRYRTMKGFSV
RRKAGWDTHGLPVEISVEQKLGLKNKSQVEGFGTDEFNREAKALVYHHINDSKEGWGKLTELMGYWVDMDSPYITCTNEY
IESVWWGLKQIFDKGLIYKDYKIVPQDPKSETVLSSHELALGYREIKDPSVYVKFKLKDSDESFLVWTTTPWTLISNVAL
CVGPDVEYVKVRTEEHGVLILAKSRISVLGKNEDGNTWEILETCTGEDLEGIEYEPLFSYVPVKKKAFFVTLGDFVSTED
GSGIVHIAPAFGADDYELLKKYDLPMLQPVARNGCFTAEVSDYEGVFFKDADKDIILALKNKGKLFKKETVTHSYPFSWR
YNVPVLYYARESWYIRTTDVAKRMMAINKEINWCPPEIGSGRFGNWLEENKDWAISRERFWGTPLPVWVSEDFQIGDDHT
SGKMFAVSSIAELKEGFIDIEGKQMKLSDALEQKFVELDLHKPFVDSVYFIKDGKTFRRTPELIDVWFDSGAMPFAQLHY
PFENKKLFENGGFPADFIAEGVDQTRGWFYTLHAIGTLIFNKPAYKNLIVNGHILDKDGQKMSKSKGNVVDPFEMMSKYG
ADSLRWYLISTSPPWRPKSFNPEELLEGQRKFFRALVNSYNFFVLYANVDEFDYSENNLPVCERSELDRWIISALNTLVK
HVEAAMENYDPTAAARHIEAFTVDDLSNWYIRRSRRRFWKGENNNDKLAAYQTLYQCLLVVSKLVAPVSPFISDWIYRNL
NEVSGKESFESVHLAYFPSVEETAIDSDLELRMKKAQIISSLVRTMREKSGIKVRQPLKRVLLPISDPRERREIEKIRTI
VLDEVNVHSLEYVDDDSGVVNKKAKPNFKVLGPKFGKDAKAVAACIRELPSSQVAKLERNGILAIDVQGKSAEITLEDIE
ILHEDIEGWLVAYDSTYKLMVALDTEIDETLRAEGLARELVSRIQSLRKDKGLEITDRIKLYLDPSELLKISIEQNLEYI
KAETLATDIDFNLDGMQSVAKTEDINGEICRMALEKK

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1078, Percent_Identity=37.847866419295, Blast_Score=721, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1078, Percent_Identity=37.847866419295, Blast_Score=721, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=789, Percent_Identity=28.5171102661597, Blast_Score=303, Evalue=8e-82,
Organism=Homo sapiens, GI268370293, Length=925, Percent_Identity=21.1891891891892, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI268370297, Length=925, Percent_Identity=21.1891891891892, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI268370295, Length=880, Percent_Identity=21.0227272727273, Blast_Score=152, Evalue=2e-36,
Organism=Escherichia coli, GI2367096, Length=817, Percent_Identity=27.5397796817625, Blast_Score=314, Evalue=2e-86,
Organism=Escherichia coli, GI1790708, Length=936, Percent_Identity=22.9700854700855, Blast_Score=181, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17541896, Length=1046, Percent_Identity=37.4760994263862, Blast_Score=669, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=827, Percent_Identity=25.5139056831923, Blast_Score=241, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17510661, Length=922, Percent_Identity=22.4511930585683, Blast_Score=186, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1062, Percent_Identity=36.8173258003767, Blast_Score=636, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=824, Percent_Identity=25.3640776699029, Blast_Score=233, Evalue=9e-62,
Organism=Saccharomyces cerevisiae, GI6321531, Length=878, Percent_Identity=22.3234624145786, Blast_Score=160, Evalue=8e-40,
Organism=Drosophila melanogaster, GI28574730, Length=1051, Percent_Identity=36.8220742150333, Blast_Score=649, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1051, Percent_Identity=36.8220742150333, Blast_Score=649, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1051, Percent_Identity=36.8220742150333, Blast_Score=649, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=787, Percent_Identity=28.843710292249, Blast_Score=283, Evalue=6e-76,
Organism=Drosophila melanogaster, GI17864482, Length=910, Percent_Identity=22.7472527472527, Blast_Score=183, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24653289, Length=910, Percent_Identity=22.7472527472527, Blast_Score=183, Evalue=7e-46,
Organism=Drosophila melanogaster, GI21355675, Length=868, Percent_Identity=20.9677419354839, Blast_Score=139, Evalue=7e-33,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 123450; Mature: 123319

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFKELPAELSYSALEAEVLAFWKKNNIFEKSIASRAEGKAFTFYDGPPTVNGKPGVHH
CCCHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHH
VFSRTIKDLICRYRTMKGFSVRRKAGWDTHGLPVEISVEQKLGLKNKSQVEGFGTDEFNR
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCHHCC
EAKALVYHHINDSKEGWGKLTELMGYWVDMDSPYITCTNEYIESVWWGLKQIFDKGLIYK
CHHEEEEEECCCCCHHHHHHHHHHHHEEECCCCEEEECHHHHHHHHHHHHHHHHCCCEEE
DYKIVPQDPKSETVLSSHELALGYREIKDPSVYVKFKLKDSDESFLVWTTTPWTLISNVA
CCEECCCCCCCCCHHCCCHHHCCHHHCCCCEEEEEEEEECCCCCEEEEECCCHHHHHCCE
LCVGPDVEYVKVRTEEHGVLILAKSRISVLGKNEDGNTWEILETCTGEDLEGIEYEPLFS
EEECCCCEEEEEEECCCCEEEEEECCEEEEECCCCCCEEHHHHHCCCCCCCCCCCCCHHC
YVPVKKKAFFVTLGDFVSTEDGSGIVHIAPAFGADDYELLKKYDLPMLQPVARNGCFTAE
CCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCHHHHHHCCCCEEEE
VSDYEGVFFKDADKDIILALKNKGKLFKKETVTHSYPFSWRYNVPVLYYARESWYIRTTD
CCCCCCEEEECCCCEEEEEECCCCCEEEHHCCCCCCCCEEEECCCEEEEECCCEEEEEHH
VAKRMMAINKEINWCPPEIGSGRFGNWLEENKDWAISRERFWGTPLPVWVSEDFQIGDDH
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCEEEHHHCCCCCCCEEECCCCCCCCCC
TSGKMFAVSSIAELKEGFIDIEGKQMKLSDALEQKFVELDLHKPFVDSVYFIKDGKTFRR
CCCCEEEHHHHHHHHHCCEECCCCEEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHC
TPELIDVWFDSGAMPFAQLHYPFENKKLFENGGFPADFIAEGVDQTRGWFYTLHAIGTLI
CCHHEEEEECCCCCCHHHEECCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHHH
FNKPAYKNLIVNGHILDKDGQKMSKSKGNVVDPFEMMSKYGADSLRWYLISTSPPWRPKS
CCCCCHHEEEEECEEECCCCHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCC
FNPEELLEGQRKFFRALVNSYNFFVLYANVDEFDYSENNLPVCERSELDRWIISALNTLV
CCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KHVEAAMENYDPTAAARHIEAFTVDDLSNWYIRRSRRRFWKGENNNDKLAAYQTLYQCLL
HHHHHHHHCCCCHHHHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VVSKLVAPVSPFISDWIYRNLNEVSGKESFESVHLAYFPSVEETAIDSDLELRMKKAQII
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCHHHHHCCCHHHHHHHHHHHH
SSLVRTMREKSGIKVRQPLKRVLLPISDPRERREIEKIRTIVLDEVNVHSLEYVDDDSGV
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
VNKKAKPNFKVLGPKFGKDAKAVAACIRELPSSQVAKLERNGILAIDVQGKSAEITLEDI
CCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCEEEHHHH
EILHEDIEGWLVAYDSTYKLMVALDTEIDETLRAEGLARELVSRIQSLRKDKGLEITDRI
HHHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
KLYLDPSELLKISIEQNLEYIKAETLATDIDFNLDGMQSVAKTEDINGEICRMALEKK
EEEECHHHHEEEEHHHCHHHHHHHHHEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
AKFKELPAELSYSALEAEVLAFWKKNNIFEKSIASRAEGKAFTFYDGPPTVNGKPGVHH
CCHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHH
VFSRTIKDLICRYRTMKGFSVRRKAGWDTHGLPVEISVEQKLGLKNKSQVEGFGTDEFNR
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCHHCC
EAKALVYHHINDSKEGWGKLTELMGYWVDMDSPYITCTNEYIESVWWGLKQIFDKGLIYK
CHHEEEEEECCCCCHHHHHHHHHHHHEEECCCCEEEECHHHHHHHHHHHHHHHHCCCEEE
DYKIVPQDPKSETVLSSHELALGYREIKDPSVYVKFKLKDSDESFLVWTTTPWTLISNVA
CCEECCCCCCCCCHHCCCHHHCCHHHCCCCEEEEEEEEECCCCCEEEEECCCHHHHHCCE
LCVGPDVEYVKVRTEEHGVLILAKSRISVLGKNEDGNTWEILETCTGEDLEGIEYEPLFS
EEECCCCEEEEEEECCCCEEEEEECCEEEEECCCCCCEEHHHHHCCCCCCCCCCCCCHHC
YVPVKKKAFFVTLGDFVSTEDGSGIVHIAPAFGADDYELLKKYDLPMLQPVARNGCFTAE
CCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCHHHHHHCCCCEEEE
VSDYEGVFFKDADKDIILALKNKGKLFKKETVTHSYPFSWRYNVPVLYYARESWYIRTTD
CCCCCCEEEECCCCEEEEEECCCCCEEEHHCCCCCCCCEEEECCCEEEEECCCEEEEEHH
VAKRMMAINKEINWCPPEIGSGRFGNWLEENKDWAISRERFWGTPLPVWVSEDFQIGDDH
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCEEEHHHCCCCCCCEEECCCCCCCCCC
TSGKMFAVSSIAELKEGFIDIEGKQMKLSDALEQKFVELDLHKPFVDSVYFIKDGKTFRR
CCCCEEEHHHHHHHHHCCEECCCCEEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHC
TPELIDVWFDSGAMPFAQLHYPFENKKLFENGGFPADFIAEGVDQTRGWFYTLHAIGTLI
CCHHEEEEECCCCCCHHHEECCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHHH
FNKPAYKNLIVNGHILDKDGQKMSKSKGNVVDPFEMMSKYGADSLRWYLISTSPPWRPKS
CCCCCHHEEEEECEEECCCCHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCC
FNPEELLEGQRKFFRALVNSYNFFVLYANVDEFDYSENNLPVCERSELDRWIISALNTLV
CCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KHVEAAMENYDPTAAARHIEAFTVDDLSNWYIRRSRRRFWKGENNNDKLAAYQTLYQCLL
HHHHHHHHCCCCHHHHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VVSKLVAPVSPFISDWIYRNLNEVSGKESFESVHLAYFPSVEETAIDSDLELRMKKAQII
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCHHHHHCCCHHHHHHHHHHHH
SSLVRTMREKSGIKVRQPLKRVLLPISDPRERREIEKIRTIVLDEVNVHSLEYVDDDSGV
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
VNKKAKPNFKVLGPKFGKDAKAVAACIRELPSSQVAKLERNGILAIDVQGKSAEITLEDI
CCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCEEEHHHH
EILHEDIEGWLVAYDSTYKLMVALDTEIDETLRAEGLARELVSRIQSLRKDKGLEITDRI
HHHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
KLYLDPSELLKISIEQNLEYIKAETLATDIDFNLDGMQSVAKTEDINGEICRMALEKK
EEEECHHHHEEEEHHHCHHHHHHHHHEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]