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The map label for this gene is hppA [H]

Identifier: 193214406

GI number: 193214406

Start: 802752

End: 804821

Strand: Direct

Name: hppA [H]

Synonym: Ctha_0689

Alternate gene names: 193214406

Gene position: 802752-804821 (Clockwise)

Preceding gene: 193214405

Following gene: 193214407

Centisome position: 24.37

GC content: 52.56

Gene sequence:

>2070_bases
ATGGATACACTCATTTATGCCATTCCCGCCGCAGGGGTCATTTCCTTGCTTTATGCCTCACTAAAAACTTCATGGGTCAC
CAAGCAACCAACCGGTACACAAGAAATGACAGAAATTGCCGGGCACATTGCTGAAGGCGCCAAAGCGTTTTTGCAACGCG
AGTATCGAATTCTGATCATTTTTGTGGTGGCCGTTGCGGCACTTTTGGCTTTTGCTAACATGGGGCGCACTGACTCGTCG
TGGCTTGTTGCTGTTAGTTTTGTGATAGGGGCGCTTTGTTCTGCGGGCGCTGGATTTATTGGCATGACGGTTGCCACAAA
GGCCAACGTGCGCACCACGCACGCAGCCAGAACTGGCCTTGCGGAAGCGCTCAATGTCGCGTTTTCCGGCGGCTTGGTCA
TGGGGCTTTCGGTTGTGGGTTTAGGTGTTTTAGGGCTTTCGGTGCTGTTTATTGTATATAGCAACCTTTTTGACGAAGTT
GGCCGGGTCATTAATGTCATTTCAGGTTTTTCGCTCGGCGCATCGTCCATTGCGCTGTTCGCACGCGTTGGCGGCGGCAT
TTATACCAAAGCGGCAGATGTAGGCGCTGACCTCGCCGGAAAAGTCTATGAAGGCATTCCCGAGGACGATCCGCGCAATC
CAGCAACCATTGCGGATAACGTGGGCGATAATGTGGGCGACGTGGCAGGCATGGGCGCTGACCTTTTTGAAAGTTACGTC
GGCTCGATTATCGGCACCATGGTTTTGGGCGCAGCTTTTGTCCCCGTATTTCAAGAAATGGGCGTTATGCCAACAGCTGC
AGTCTTGCTTCCACTGGTTTTGGCTGGTGTTGGAATTATCGTTTCCATTCTCGGTTCGTTTTTTGTAAAGGTCAAAGAAG
GCGGCAACCCACAAACCGCGCTCAACACGGGCGAGTTTGGCGCATCGGGCGTCATGGCCGTTCTCAGCTATTTTATCATT
ACGATGTTTCTCCCTGAAAAATGGGAGTTGGATGGCATGACTTACACCTCACAAAATATCTTTTTTGCAGTGCTTATCGG
ACTCGTTTCTGGCGTGCTTATCGGCATCATCACAGAATATTATTGCTCCACACACAACAAACCGGTGCTTGGCATCGCGT
ATCAAAGCGTGACTGGCGCGGCGACAAACATCATTGCAGGATTGGGCGTTGGCATGTTTTCGACCGGCTTCCCAATTATC
GTGCTTTCTATCGCAATCGTGGCTTCGCATTATTTTGCCGGCCTGTTCGGCATCGCGATTGCCGCGCTCGGCATGCTTTC
CGTTACAGGCATTCAGCTTGCCGTTGATGCTTATGGACCGATTTCCGACAACGCGGGCGGTATCGCCGAAATGTCGGGCA
TGCCACCGGAAGTTCGCGAGAGAACCGACACATTGGACGCCGTCGGAAACACCACTGCCGCCATCGGCAAAGGCTTTGCG
ATTGGCAGTGCTGCATTAACCGCACTCGCACTTTTTGCCGCGTTCATGCAACAAGCGAATATTTCTTCGATCGATATTTC
GCATCCGGTAATTATGGCCGGTTTATTAATCGGTGCAATGTTGCCGTTTGTCTTTAGCGCCATGGCAATGGGCGCAGTTG
GCCGCGCAGCTCGCGACATGATTACCGAAGTTGGCCGCCAGTTTCGCGAAATCAAAGGCTTGCGCGAAGGAACAGCCAAA
GCGGAATATGCCAAGTGCGTGGATATTTCCACTAAAGCTGCGCTTCGCGAAATGATTTTGCCCGGCCTGATGGGCGTATT
TGTTCCGGTCATCGTCGGCTTTACGTCTAAGGATATGCTCGGCGGCCTGCTGGCCGGCGTCACGAGTTCCGGTGTTTTGA
TGGCGATTTTCCAATCCAACGCGGGCGGCGCTTGGGACAACGCGAAAAAACGCATCGAAGGAAAGTTGGAAATCGACGGC
GTCATGTATGGCAAAGGTTCCGATGTGCATAAAGCTGCCGTCGTGGGCGACACTGTCGGCGATCCGTTCAAAGACACCAG
CGGCCCAAGCCTCAACATTTTGATGAAGCTTATCGCGGTGGTGGCGCTCGTTATTGCACCGCTGCTTTAA

Upstream 100 bases:

>100_bases
GGCCATCATCCGCTCTCTGGCTGACTATGTAGTTTCTTTCGGCACCAAGCGCCTGATGTCGCTGAAATCCATTTCTTAAA
AACCAAACTGCAGAAAGAAC

Downstream 100 bases:

>100_bases
CTTTTCGCCCTGTTTTTTTGACAAAGAAAATTCGTCTTTATATTTTGCGGCCTCTTTTTTAGAGGCCGTTTTTTTTCACC
TGTCGCCTATTTTGGCTGAT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MDTLIYAIPAAGVISLLYASLKTSWVTKQPTGTQEMTEIAGHIAEGAKAFLQREYRILIIFVVAVAALLAFANMGRTDSS
WLVAVSFVIGALCSAGAGFIGMTVATKANVRTTHAARTGLAEALNVAFSGGLVMGLSVVGLGVLGLSVLFIVYSNLFDEV
GRVINVISGFSLGASSIALFARVGGGIYTKAADVGADLAGKVYEGIPEDDPRNPATIADNVGDNVGDVAGMGADLFESYV
GSIIGTMVLGAAFVPVFQEMGVMPTAAVLLPLVLAGVGIIVSILGSFFVKVKEGGNPQTALNTGEFGASGVMAVLSYFII
TMFLPEKWELDGMTYTSQNIFFAVLIGLVSGVLIGIITEYYCSTHNKPVLGIAYQSVTGAATNIIAGLGVGMFSTGFPII
VLSIAIVASHYFAGLFGIAIAALGMLSVTGIQLAVDAYGPISDNAGGIAEMSGMPPEVRERTDTLDAVGNTTAAIGKGFA
IGSAALTALALFAAFMQQANISSIDISHPVIMAGLLIGAMLPFVFSAMAMGAVGRAARDMITEVGRQFREIKGLREGTAK
AEYAKCVDISTKAALREMILPGLMGVFVPVIVGFTSKDMLGGLLAGVTSSGVLMAIFQSNAGGAWDNAKKRIEGKLEIDG
VMYGKGSDVHKAAVVGDTVGDPFKDTSGPSLNILMKLIAVVALVIAPLL

Sequences:

>Translated_689_residues
MDTLIYAIPAAGVISLLYASLKTSWVTKQPTGTQEMTEIAGHIAEGAKAFLQREYRILIIFVVAVAALLAFANMGRTDSS
WLVAVSFVIGALCSAGAGFIGMTVATKANVRTTHAARTGLAEALNVAFSGGLVMGLSVVGLGVLGLSVLFIVYSNLFDEV
GRVINVISGFSLGASSIALFARVGGGIYTKAADVGADLAGKVYEGIPEDDPRNPATIADNVGDNVGDVAGMGADLFESYV
GSIIGTMVLGAAFVPVFQEMGVMPTAAVLLPLVLAGVGIIVSILGSFFVKVKEGGNPQTALNTGEFGASGVMAVLSYFII
TMFLPEKWELDGMTYTSQNIFFAVLIGLVSGVLIGIITEYYCSTHNKPVLGIAYQSVTGAATNIIAGLGVGMFSTGFPII
VLSIAIVASHYFAGLFGIAIAALGMLSVTGIQLAVDAYGPISDNAGGIAEMSGMPPEVRERTDTLDAVGNTTAAIGKGFA
IGSAALTALALFAAFMQQANISSIDISHPVIMAGLLIGAMLPFVFSAMAMGAVGRAARDMITEVGRQFREIKGLREGTAK
AEYAKCVDISTKAALREMILPGLMGVFVPVIVGFTSKDMLGGLLAGVTSSGVLMAIFQSNAGGAWDNAKKRIEGKLEIDG
VMYGKGSDVHKAAVVGDTVGDPFKDTSGPSLNILMKLIAVVALVIAPLL
>Mature_689_residues
MDTLIYAIPAAGVISLLYASLKTSWVTKQPTGTQEMTEIAGHIAEGAKAFLQREYRILIIFVVAVAALLAFANMGRTDSS
WLVAVSFVIGALCSAGAGFIGMTVATKANVRTTHAARTGLAEALNVAFSGGLVMGLSVVGLGVLGLSVLFIVYSNLFDEV
GRVINVISGFSLGASSIALFARVGGGIYTKAADVGADLAGKVYEGIPEDDPRNPATIADNVGDNVGDVAGMGADLFESYV
GSIIGTMVLGAAFVPVFQEMGVMPTAAVLLPLVLAGVGIIVSILGSFFVKVKEGGNPQTALNTGEFGASGVMAVLSYFII
TMFLPEKWELDGMTYTSQNIFFAVLIGLVSGVLIGIITEYYCSTHNKPVLGIAYQSVTGAATNIIAGLGVGMFSTGFPII
VLSIAIVASHYFAGLFGIAIAALGMLSVTGIQLAVDAYGPISDNAGGIAEMSGMPPEVRERTDTLDAVGNTTAAIGKGFA
IGSAALTALALFAAFMQQANISSIDISHPVIMAGLLIGAMLPFVFSAMAMGAVGRAARDMITEVGRQFREIKGLREGTAK
AEYAKCVDISTKAALREMILPGLMGVFVPVIVGFTSKDMLGGLLAGVTSSGVLMAIFQSNAGGAWDNAKKRIEGKLEIDG
VMYGKGSDVHKAAVVGDTVGDPFKDTSGPSLNILMKLIAVVALVIAPLL

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 70970; Mature: 70970

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLIYAIPAAGVISLLYASLKTSWVTKQPTGTQEMTEIAGHIAEGAKAFLQREYRILII
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVAVAALLAFANMGRTDSSWLVAVSFVIGALCSAGAGFIGMTVATKANVRTTHAARTGL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
AEALNVAFSGGLVMGLSVVGLGVLGLSVLFIVYSNLFDEVGRVINVISGFSLGASSIALF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ARVGGGIYTKAADVGADLAGKVYEGIPEDDPRNPATIADNVGDNVGDVAGMGADLFESYV
HHHCCCCEEHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHCCCHHHHHHHH
GSIIGTMVLGAAFVPVFQEMGVMPTAAVLLPLVLAGVGIIVSILGSFFVKVKEGGNPQTA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHCCCCCCCCC
LNTGEFGASGVMAVLSYFIITMFLPEKWELDGMTYTSQNIFFAVLIGLVSGVLIGIITEY
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
YCSTHNKPVLGIAYQSVTGAATNIIAGLGVGMFSTGFPIIVLSIAIVASHYFAGLFGIAI
HHCCCCCCEEEEEHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AALGMLSVTGIQLAVDAYGPISDNAGGIAEMSGMPPEVRERTDTLDAVGNTTAAIGKGFA
HHHHHHHHHHHEEEEECCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCH
IGSAALTALALFAAFMQQANISSIDISHPVIMAGLLIGAMLPFVFSAMAMGAVGRAARDM
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITEVGRQFREIKGLREGTAKAEYAKCVDISTKAALREMILPGLMGVFVPVIVGFTSKDML
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GGLLAGVTSSGVLMAIFQSNAGGAWDNAKKRIEGKLEIDGVMYGKGSDVHKAAVVGDTVG
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCEEEEEEEECCCCCCHHHHHCCCCCC
DPFKDTSGPSLNILMKLIAVVALVIAPLL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDTLIYAIPAAGVISLLYASLKTSWVTKQPTGTQEMTEIAGHIAEGAKAFLQREYRILII
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVAVAALLAFANMGRTDSSWLVAVSFVIGALCSAGAGFIGMTVATKANVRTTHAARTGL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
AEALNVAFSGGLVMGLSVVGLGVLGLSVLFIVYSNLFDEVGRVINVISGFSLGASSIALF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ARVGGGIYTKAADVGADLAGKVYEGIPEDDPRNPATIADNVGDNVGDVAGMGADLFESYV
HHHCCCCEEHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHCCCHHHHHHHH
GSIIGTMVLGAAFVPVFQEMGVMPTAAVLLPLVLAGVGIIVSILGSFFVKVKEGGNPQTA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHCCCCCCCCC
LNTGEFGASGVMAVLSYFIITMFLPEKWELDGMTYTSQNIFFAVLIGLVSGVLIGIITEY
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
YCSTHNKPVLGIAYQSVTGAATNIIAGLGVGMFSTGFPIIVLSIAIVASHYFAGLFGIAI
HHCCCCCCEEEEEHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AALGMLSVTGIQLAVDAYGPISDNAGGIAEMSGMPPEVRERTDTLDAVGNTTAAIGKGFA
HHHHHHHHHHHEEEEECCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCH
IGSAALTALALFAAFMQQANISSIDISHPVIMAGLLIGAMLPFVFSAMAMGAVGRAARDM
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITEVGRQFREIKGLREGTAKAEYAKCVDISTKAALREMILPGLMGVFVPVIVGFTSKDML
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GGLLAGVTSSGVLMAIFQSNAGGAWDNAKKRIEGKLEIDGVMYGKGSDVHKAAVVGDTVG
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCEEEEEEEECCCCCCHHHHHCCCCCC
DPFKDTSGPSLNILMKLIAVVALVIAPLL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA