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The map label for this gene is nudF [H]

Identifier: 193214340

GI number: 193214340

Start: 731900

End: 732463

Strand: Direct

Name: nudF [H]

Synonym: Ctha_0622

Alternate gene names: 193214340

Gene position: 731900-732463 (Clockwise)

Preceding gene: 193214339

Following gene: 193214341

Centisome position: 22.22

GC content: 50.71

Gene sequence:

>564_bases
ATGTCAAAATTTCCCAACGACCCAAAACCGTGGAAAACCTTAAGTTCAAAATATCTTTTTAATCGGCCTTGGCTCACGAT
GCGCCAAGATCATGTTGTGCTGCCAACGGGCGGCGAAGTCGAAGAATTTTATGTGTGGGAATATCCGGCGTGGGTAAATG
TGGTGGCCATTACGAAGGCGAACGAAGTGGTGCTGATTCGCCAATATCGCTACGCCATCGGCGAAGTGTATTATGAAATT
CCCGCCGGCGTGCATGACAAACCGGAGGAATCTTTGCTCGAGGCGGCCAAACGCGAGCTGCTCGAGGAAACCGGTTTCGG
CGGCGGCACTTGGCAGCCTTGGATGGAACTTTGCGCCAATCCCGCCATTCAAACCAACATTACGCACACATTTTTAGCGA
CCGATGTTGAACCCGTTCAAGCGCAAACGCTGGAAGCAACGGAGGAAATTTCCGTGCATCTTCTGCCCGTCAATGCGTTG
AAAAAGCTCATCTTGGACAGGGAAATAATTCAAGCGCTGCACACCGCGCCGCTCTTGAAATATCTTCTAACTCGGGAAGA
TTGA

Upstream 100 bases:

>100_bases
CAATGTGGTCATTTCAGTGATTGGCGCGGTGCTGCTGGCCTTGGTTTCGGGCGTAAAAATCAGTCGCTCGCGTTAGACAA
AAACCTTAAAATCAAATACC

Downstream 100 bases:

>100_bases
GAATAAAAATTCTCTCGCCCTGAACGGCCAAATTTTTCCAAAAGAGAAAAAGCCCACTCGTTGAATAGCAGCTCTGGCCA
ATTTGTCATGCTGAACGGCT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSKFPNDPKPWKTLSSKYLFNRPWLTMRQDHVVLPTGGEVEEFYVWEYPAWVNVVAITKANEVVLIRQYRYAIGEVYYEI
PAGVHDKPEESLLEAAKRELLEETGFGGGTWQPWMELCANPAIQTNITHTFLATDVEPVQAQTLEATEEISVHLLPVNAL
KKLILDREIIQALHTAPLLKYLLTRED

Sequences:

>Translated_187_residues
MSKFPNDPKPWKTLSSKYLFNRPWLTMRQDHVVLPTGGEVEEFYVWEYPAWVNVVAITKANEVVLIRQYRYAIGEVYYEI
PAGVHDKPEESLLEAAKRELLEETGFGGGTWQPWMELCANPAIQTNITHTFLATDVEPVQAQTLEATEEISVHLLPVNAL
KKLILDREIIQALHTAPLLKYLLTRED
>Mature_186_residues
SKFPNDPKPWKTLSSKYLFNRPWLTMRQDHVVLPTGGEVEEFYVWEYPAWVNVVAITKANEVVLIRQYRYAIGEVYYEIP
AGVHDKPEESLLEAAKRELLEETGFGGGTWQPWMELCANPAIQTNITHTFLATDVEPVQAQTLEATEEISVHLLPVNALK
KLILDREIIQALHTAPLLKYLLTRED

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 21447; Mature: 21316

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFPNDPKPWKTLSSKYLFNRPWLTMRQDHVVLPTGGEVEEFYVWEYPAWVNVVAITKA
CCCCCCCCCHHHHHHHCHHCCCCCEEECCCEEEECCCCCCEEEEEEECCCEEEEEEEECC
NEVVLIRQYRYAIGEVYYEIPAGVHDKPEESLLEAAKRELLEETGFGGGTWQPWMELCAN
CCEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
PAIQTNITHTFLATDVEPVQAQTLEATEEISVHLLPVNALKKLILDREIIQALHTAPLLK
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
YLLTRED
HHHHCCC
>Mature Secondary Structure 
SKFPNDPKPWKTLSSKYLFNRPWLTMRQDHVVLPTGGEVEEFYVWEYPAWVNVVAITKA
CCCCCCCCHHHHHHHCHHCCCCCEEECCCEEEECCCCCCEEEEEEECCCEEEEEEEECC
NEVVLIRQYRYAIGEVYYEIPAGVHDKPEESLLEAAKRELLEETGFGGGTWQPWMELCAN
CCEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
PAIQTNITHTFLATDVEPVQAQTLEATEEISVHLLPVNALKKLILDREIIQALHTAPLLK
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
YLLTRED
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]